Pathophysiology of Spinal Cord Injury (SCI)
Spinal cord injury (SCI) leads to paralysis, sensory, and autonomic nervous system dysfunctions. However, the pathophysiology of SCI is complex, and not limited to the nervous system. Indeed, several other organs and tissue are also affected by the injury, directly or not, acutely or chronically, wh...
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| Year of Publication: | 2022 |
| Language: | English |
| Physical Description: | 1 electronic resource (258 p.) |
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Geoffroy, Cédric edt Pathophysiology of Spinal Cord Injury (SCI) Pathophysiology of Spinal Cord Injury Basel MDPI - Multidisciplinary Digital Publishing Institute 2022 1 electronic resource (258 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier Spinal cord injury (SCI) leads to paralysis, sensory, and autonomic nervous system dysfunctions. However, the pathophysiology of SCI is complex, and not limited to the nervous system. Indeed, several other organs and tissue are also affected by the injury, directly or not, acutely or chronically, which induces numerous health complications. Although a lot of research has been performed to repair motor and sensory functions, SCI-induced health issues are less studied, although they represent a major concern among patients. There is a gap of knowledge in pre-clinical models studying these SCI-induced health complications that limits translational applications in humans. This reprint describes several aspects of the pathophysiology of spinal cord injuries. This includes, but is not limited to, the impact of SCI on cardiovascular and respiratory functions, bladder and bowel function, autonomic dysreflexia, liver pathology, metabolic syndrome, bones and muscles loss, and cognitive functions. English Medicine bicssc Neurosciences bicssc micturition external urethral sphincter spinal cord injury serotonin electromyogram fecal microbiota transplant inflammation anxiety rehabilitation autonomic dysreflexia immune dysfunction SCI-IDS primary afferents nociceptor reach-to-grasp forelimb function upper extremity function cardiovascular contusion neuroplasticity osteopenia bone loss recovery of function monoamines GABA neuromodulation pain spasticity ionic plasticity repetitive transcranial magnetic stimulation phrenic motor network motoneuron excitability diaphragm muscle spinal cord injury severity cardiometabolic disease liver and cardiac dysfunctions fibrosis pathophysiology oxidative stress contusion model respiratory function diaphragmatic activity phrenic motoneurons neuroinflammation cytokines tumor necrosis factor immune cells microglia 3-0365-5888-8 Alilain, Warren edt Geoffroy, Cédric oth Alilain, Warren oth |
| language |
English |
| format |
eBook |
| author2 |
Alilain, Warren Geoffroy, Cédric Alilain, Warren |
| author_facet |
Alilain, Warren Geoffroy, Cédric Alilain, Warren |
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c g cg w a wa |
| author2_role |
HerausgeberIn Sonstige Sonstige |
| title |
Pathophysiology of Spinal Cord Injury (SCI) |
| spellingShingle |
Pathophysiology of Spinal Cord Injury (SCI) |
| title_full |
Pathophysiology of Spinal Cord Injury (SCI) |
| title_fullStr |
Pathophysiology of Spinal Cord Injury (SCI) |
| title_full_unstemmed |
Pathophysiology of Spinal Cord Injury (SCI) |
| title_auth |
Pathophysiology of Spinal Cord Injury (SCI) |
| title_alt |
Pathophysiology of Spinal Cord Injury |
| title_new |
Pathophysiology of Spinal Cord Injury (SCI) |
| title_sort |
pathophysiology of spinal cord injury (sci) |
| publisher |
MDPI - Multidisciplinary Digital Publishing Institute |
| publishDate |
2022 |
| physical |
1 electronic resource (258 p.) |
| isbn |
3-0365-5887-X 3-0365-5888-8 |
| illustrated |
Not Illustrated |
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Pathophysiology of Spinal Cord Injury (SCI) |
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