State-of-Art in Innate Immunity
The innate immune system is the first line of defense against bacterial and viral infections and sterile inflammation through the recognition of pathogen-associated molecular patterns (PAMPs) by pathogen recognition receptors (PRRs) resulting in the production of proinflammatory and antiviral cytoki...
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| Year of Publication: | 2022 |
| Language: | English |
| Physical Description: | 1 electronic resource (188 p.) |
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Fischer, Silvia edt State-of-Art in Innate Immunity MDPI - Multidisciplinary Digital Publishing Institute 2022 1 electronic resource (188 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier The innate immune system is the first line of defense against bacterial and viral infections and sterile inflammation through the recognition of pathogen-associated molecular patterns (PAMPs) by pathogen recognition receptors (PRRs) resulting in the production of proinflammatory and antiviral cytokines and chemokines. Several damage-associated molecular patterns (DAMPs), which were released by passive or active mechanisms under sterile conditions, are additionally recognized by PRRs and can cause or even aggravate the inflammatory response. In this special issue many aspects of innate immunity are summarized. Mechanisms of different DAMPs to induce pro- and anti-inflammatory activities, functions of different immune cells, as well as the crosstalk between coagulation and innate immunity were described. Furthermore, aspects of autoinflammatory diseases, types of programmed cell death pathways, and insect immunity are covered. Finally, therapeutic options for the treatment of diseases related to autoimmunity or infections are suggested. Overall, this special issue presents a broad overview of activities related to sterile inflammation and defense mechanisms of innate immunity. English Medicine bicssc inflammation type I interferons interleukin-1β crosstalk hepatic non-parenchymal cells albumin chronic liver diseases bacteria cytomegalovirus endothelin receptor repurposing cell culture Drosophila suzukii hemocytes plasmatocytes extracellular traps HMGB1 RAGE TLR4 DAMP SIRT1 α7-nicotinic acetylcholine receptor nociceptor cancer COVID-19 proteostasis autoinflammation ribosomopathies proteinopathies proteasomopathies extracellular RNA cytokines macrophages endothelial cells toll-like receptors angiogenesis γδ T cells gamma delta T cells proliferation macrophage polarization neutrophils neutrophil extracellular traps NETs ischemia PANoptosis PANoptosome pyroptosis apoptosis necroptosis inflammatory cell death inflammasome innate immunity infection NLR caspase IRF1 ZBP1 RIPK1 RIPK3 MLKL NLRP3 AIM2 Pyrin caspase-1 ASC caspase-8 caspase-3 caspase-7 plasticity redundancy SMOC1 thrombin 3-0365-5323-1 Deindl, Elisabeth edt Fischer, Silvia oth Deindl, Elisabeth oth |
| language |
English |
| format |
eBook |
| author2 |
Deindl, Elisabeth Fischer, Silvia Deindl, Elisabeth |
| author_facet |
Deindl, Elisabeth Fischer, Silvia Deindl, Elisabeth |
| author2_variant |
s f sf e d ed |
| author2_role |
HerausgeberIn Sonstige Sonstige |
| title |
State-of-Art in Innate Immunity |
| spellingShingle |
State-of-Art in Innate Immunity |
| title_full |
State-of-Art in Innate Immunity |
| title_fullStr |
State-of-Art in Innate Immunity |
| title_full_unstemmed |
State-of-Art in Innate Immunity |
| title_auth |
State-of-Art in Innate Immunity |
| title_new |
State-of-Art in Innate Immunity |
| title_sort |
state-of-art in innate immunity |
| publisher |
MDPI - Multidisciplinary Digital Publishing Institute |
| publishDate |
2022 |
| physical |
1 electronic resource (188 p.) |
| isbn |
3-0365-5324-X 3-0365-5323-1 |
| illustrated |
Not Illustrated |
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AT fischersilvia stateofartininnateimmunity AT deindlelisabeth stateofartininnateimmunity |
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n |
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(CKB)5670000000391624 (oapen)https://directory.doabooks.org/handle/20.500.12854/93217 (EXLCZ)995670000000391624 |
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State-of-Art in Innate Immunity |
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