Model-Based Tools for Pharmaceutical Manufacturing Processes / / edited by Krist V. Gernaey, René Schenkendorf, and others.

• TeilnehmendeR: Schenkendorf, René,; Gernaey, Krist V.,
• Place / Publishing House: [Place of publication not identified] : : MDPI AG,, 2020.
• Year of Publication: 2020
• Language: English
• Physical Description: 1 online resource (188 pages)

The Special Issue on "Model-Based Tools for Pharmaceutical Manufacturing Processes" will curate novel advances in the development and application of model-based tools to address ever-present challenges of the traditional pharmaceutical manufacturing practice as well as new trends. This book provides a collection of nine papers on original advances in the model-based process unit, system-level, quality-by-design under uncertainty, and decision-making applications of pharmaceutical manufacturing processes.

Table of Contents

About the Special Issue Editors -- Ren ´e Schenkendorf, Dimitrios I. Gerogiorgis, Seyed Soheil Mansouri and Krist V. Gernaey Model-Based Tools for Pharmaceutical Manufacturing Processes -- Robert T. Giessmann, Niels Krausch, Felix Kaspar, Mariano Nicolas Cruz Bournazou, Anke Wagner, Peter Neubauer and Matthias Gimpel Dynamic Modelling of Phosphorolytic Cleavage Catalyzed by Pyrimidine-Nucleoside Phosphorylase -- Andrew B. Cuthbertson, Alistair D. Rodman, Samir Diab and Dimitrios I. Gerogiorgis Dynamic Modelling and Optimisation of the Batch Enzymatic Synthesis of Amoxicillin -- Satyajeet Bhonsale, Carlos Andr´e Mu ˜noz L ´opez and Jan Van Impe Global Sensitivity Analysis of aSpray Drying Process -- Xiangzhong Xie and Ren´e Schenkendorf Robust Process Design in Pharmaceutical Manufacturing under Batch-to-Batch Variation -- Christos Varsakelis, Sandrine Dessoy, Moritz von Stosch and Alexander Pysik Show Me the Money! Process Modeling in Pharma from the Investor's Point of View.