Cyclic nucleotide signaling and the cardiovascular system / / edited by Thomas Brand and Enno Klussmann.
The cyclic nucleotides 3',5'-adenosine monophosphate (cAMP) and 3',5'-cyclic guanosine monophosphate (cGMP) play important roles in the control of cardiovascular function under physiological and pathological conditions. In this book, which is a reprint of a Special Issue of the J...
Saved in:
TeilnehmendeR: | |
---|---|
Place / Publishing House: | Basel, Switzerland : : MDPI - Multidisciplinary Digital Publishing Institute,, [2018] ©2018 |
Year of Publication: | 2018 |
Language: | English |
Physical Description: | 1 online resource (306 pages) :; illustrations |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
993562260804498 |
---|---|
ctrlnum |
(CKB)4920000000095212 (NjHacI)994920000000095212 (EXLCZ)994920000000095212 |
collection |
bib_alma |
record_format |
marc |
spelling |
Cyclic nucleotide signaling and the cardiovascular system / edited by Thomas Brand and Enno Klussmann. Basel, Switzerland : MDPI - Multidisciplinary Digital Publishing Institute, [2018] ©2018 1 online resource (306 pages) : illustrations text txt rdacontent computer c rdamedia online resource cr rdacarrier Description based on publisher supplied metadata and other sources. The cyclic nucleotides 3',5'-adenosine monophosphate (cAMP) and 3',5'-cyclic guanosine monophosphate (cGMP) play important roles in the control of cardiovascular function under physiological and pathological conditions. In this book, which is a reprint of a Special Issue of the Journal of Cardiovascular Development and Disease entitled "Cyclic Nucleotide Signaling and the Cardiovascular System", internationally recognized experts give an overview of this vibrant scientific field. The first series of articles deal with the localization and function of membrane-bound and soluble adenylate cyclases, followed by articles on the roles of phosphodiesterase isoforms in the heart. Cyclic nucleotide signaling takes place in nanodomains and the A-kinase anchor proteins (AKAPS) are essential for the compartmentalized assembly of signaling proteins into functional complexes. Reviews on the role of AKAP proteins in the physiology and pathophysiology of the heart are also included in this book. Cyclic nucleotides act through effector proteins and articles on EPAC and POPDC proteins inform the reader of recent developments on these topics. A major advancement in our understanding of cyclic nucleotide signaling came through the use of genetically encoded cAMP sensor molecules, and a series of articles review the current insight that these reporter molecules have provided. The final set of articles in this book deals with the association of the cyclic nucleotide pathway and cardiovascular disease as well as the development of novel therapeutic approaches. Includes bibliographical references. Nucleotides. 3-03842-989-9 Brand, Thomas, editor. Klussmann, Enno, editor. |
language |
English |
format |
eBook |
author2 |
Brand, Thomas, Klussmann, Enno, |
author_facet |
Brand, Thomas, Klussmann, Enno, |
author2_variant |
t b tb e k ek |
author2_role |
TeilnehmendeR TeilnehmendeR |
title |
Cyclic nucleotide signaling and the cardiovascular system / |
spellingShingle |
Cyclic nucleotide signaling and the cardiovascular system / |
title_full |
Cyclic nucleotide signaling and the cardiovascular system / edited by Thomas Brand and Enno Klussmann. |
title_fullStr |
Cyclic nucleotide signaling and the cardiovascular system / edited by Thomas Brand and Enno Klussmann. |
title_full_unstemmed |
Cyclic nucleotide signaling and the cardiovascular system / edited by Thomas Brand and Enno Klussmann. |
title_auth |
Cyclic nucleotide signaling and the cardiovascular system / |
title_new |
Cyclic nucleotide signaling and the cardiovascular system / |
title_sort |
cyclic nucleotide signaling and the cardiovascular system / |
publisher |
MDPI - Multidisciplinary Digital Publishing Institute, |
publishDate |
2018 |
physical |
1 online resource (306 pages) : illustrations |
isbn |
3-03842-989-9 |
callnumber-first |
Q - Science |
callnumber-subject |
QP - Physiology |
callnumber-label |
QP625 |
callnumber-sort |
QP 3625 N89 C935 42018 |
illustrated |
Illustrated |
dewey-hundreds |
500 - Science |
dewey-tens |
540 - Chemistry |
dewey-ones |
547 - Organic chemistry |
dewey-full |
547.79 |
dewey-sort |
3547.79 |
dewey-raw |
547.79 |
dewey-search |
547.79 |
work_keys_str_mv |
AT brandthomas cyclicnucleotidesignalingandthecardiovascularsystem AT klussmannenno cyclicnucleotidesignalingandthecardiovascularsystem |
status_str |
n |
ids_txt_mv |
(CKB)4920000000095212 (NjHacI)994920000000095212 (EXLCZ)994920000000095212 |
carrierType_str_mv |
cr |
is_hierarchy_title |
Cyclic nucleotide signaling and the cardiovascular system / |
author2_original_writing_str_mv |
noLinkedField noLinkedField |
_version_ |
1764985506180890624 |
fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>02650nam a2200313 4500</leader><controlfield tag="001">993562260804498</controlfield><controlfield tag="005">20230221100949.0</controlfield><controlfield tag="006">m o d </controlfield><controlfield tag="007">cr |||||||||||</controlfield><controlfield tag="008">230221s2018 sz a ob 000 0 eng d</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(CKB)4920000000095212</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(NjHacI)994920000000095212</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(EXLCZ)994920000000095212</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">NjHacI</subfield><subfield code="b">eng</subfield><subfield code="e">rda</subfield><subfield code="c">NjHacl</subfield></datafield><datafield tag="050" ind1=" " ind2="4"><subfield code="a">QP625.N89</subfield><subfield code="b">.C935 2018</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">547.79</subfield><subfield code="2">23</subfield></datafield><datafield tag="245" ind1="0" ind2="0"><subfield code="a">Cyclic nucleotide signaling and the cardiovascular system /</subfield><subfield code="c">edited by Thomas Brand and Enno Klussmann.</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Basel, Switzerland :</subfield><subfield code="b">MDPI - Multidisciplinary Digital Publishing Institute,</subfield><subfield code="c">[2018]</subfield></datafield><datafield tag="264" ind1=" " ind2="4"><subfield code="c">©2018</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 online resource (306 pages) :</subfield><subfield code="b">illustrations</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">computer</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">online resource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="588" ind1=" " ind2=" "><subfield code="a">Description based on publisher supplied metadata and other sources.</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The cyclic nucleotides 3',5'-adenosine monophosphate (cAMP) and 3',5'-cyclic guanosine monophosphate (cGMP) play important roles in the control of cardiovascular function under physiological and pathological conditions. In this book, which is a reprint of a Special Issue of the Journal of Cardiovascular Development and Disease entitled "Cyclic Nucleotide Signaling and the Cardiovascular System", internationally recognized experts give an overview of this vibrant scientific field. The first series of articles deal with the localization and function of membrane-bound and soluble adenylate cyclases, followed by articles on the roles of phosphodiesterase isoforms in the heart. Cyclic nucleotide signaling takes place in nanodomains and the A-kinase anchor proteins (AKAPS) are essential for the compartmentalized assembly of signaling proteins into functional complexes. Reviews on the role of AKAP proteins in the physiology and pathophysiology of the heart are also included in this book. Cyclic nucleotides act through effector proteins and articles on EPAC and POPDC proteins inform the reader of recent developments on these topics. A major advancement in our understanding of cyclic nucleotide signaling came through the use of genetically encoded cAMP sensor molecules, and a series of articles review the current insight that these reporter molecules have provided. The final set of articles in this book deals with the association of the cyclic nucleotide pathway and cardiovascular disease as well as the development of novel therapeutic approaches.</subfield></datafield><datafield tag="504" ind1=" " ind2=" "><subfield code="a">Includes bibliographical references.</subfield></datafield><datafield tag="650" ind1=" " ind2="0"><subfield code="a">Nucleotides.</subfield></datafield><datafield tag="776" ind1=" " ind2=" "><subfield code="z">3-03842-989-9</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Brand, Thomas,</subfield><subfield code="e">editor.</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Klussmann, Enno,</subfield><subfield code="e">editor.</subfield></datafield><datafield tag="906" ind1=" " ind2=" "><subfield code="a">BOOK</subfield></datafield><datafield tag="ADM" ind1=" " ind2=" "><subfield code="b">2023-03-01 01:52:00 Europe/Vienna</subfield><subfield code="f">system</subfield><subfield code="c">marc21</subfield><subfield code="a">2019-11-10 04:18:40 Europe/Vienna</subfield><subfield code="g">false</subfield></datafield><datafield tag="AVE" ind1=" " ind2=" "><subfield code="P">DOAB Directory of Open Access Books</subfield><subfield code="x">https://eu02.alma.exlibrisgroup.com/view/uresolver/43ACC_OEAW/openurl?u.ignore_date_coverage=true&portfolio_pid=5338013020004498&Force_direct=true</subfield><subfield code="Z">5338013020004498</subfield><subfield code="8">5338013020004498</subfield></datafield></record></collection> |