Major Histocompatibility Complex (MHC) in Health and Disease / / edited by Jerzy K. Kulski, Takashi Shiina and Johannes M. Dijkstra.

The major histocompatibility complex (MHC) is a highly polymorphic and diverse multigene locus in all jawed vertebrate species that has an integral role in adaptive/innate immune systems, transplantation, and infectious and autoimmune diseases. The MHC supra-locus in mammalian vertebrates is usually...

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Bibliographic Details
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Place / Publishing House:Basel, Switzerland : : MDPI - Multidisciplinary Digital Publishing Institute,, 2020.
Year of Publication:2020
Language:English
Physical Description:1 online resource (375 pages)
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Table of Contents:
  • About the Special Issue Editors
  • Genomic Diversity of the Major Histocompatibility Complex in Health and Disease
  • MHC Genomics and Disease: Looking Back to Go Forward
  • The Cynomolgus Macaque MHC Polymorphism in Experimental Medicine
  • MHC Evolution in the Era of Genomics: Phase 1.0
  • Major Histocompatibility Complex (MHC) Genes and Disease Resistance in Fish
  • An RNA Metabolism and Surveillance Quartet in the Major Histocompatibility Complex
  • Long Noncoding RNA HCPS, a Hybrid HLA Class I Endogenous Retroviral Gene: Structure, Expression, and Disease Associations
  • The Major Histocompatibility Complex of Old World Camels-A Synopsis
  • Intramolecular Domain Movements of Free and Bound pMHC and TCR Proteins: A Molecular Dynamics Simulation Study
  • Unusual Placement of an EBV Epitope into the Groove of the Ankylosing Spondylitis-Associated HLA-B27 Allele Allows CD8+ T Cell Activation
  • HLA-DQA1 and HLA-DQB1 Alleles, Conferring Susceptibility to Celiac Disease and Type 1 Diabetes, Are More Expressed Than Non-Predisposing Alleles and Are Coordinately Regulated
  • A New Pedigree-Based SNP Haplotype Method for Genomic Polymorphism and Genetic Studies
  • HLA-E Polymorphism Determines Susceptibility to BK Virus Nephropathy after Living-Donor Kidney Transplant
  • Distribution of Killer-Cell Immunoglobulin-Like Receptor Genes and Combinations of Their Human Leucocyte Antigen Ligands in 11 Ethnic Populations in China
  • Role of MHC-I Expression on Spinal Motoneuron Survival and Glial Reactions Following Ventral Root Crush in Mice
  • Genetic Association between Swine Leukocyte antigen Class II Haplotypes and Reproduction Traits in Microminipigs
  • Genetic Diversity and Differentiation at Structurally Varying MHC Haplotypes and Microsatellites in Bottlenecked Populations of Endangered Crested Ibis
  • Reproductive Strategy Inferred from Major Histocompatibility Complex-Based Inter-Individual, Sperm-Egg, and Mother-Fetus Recognitions in Giant Pandas (Ailuropoda melanoleuca)
  • Discovery of a Novel MHC Class I Lineage in Teleost Fish which Shows Unprecedented Levels of Ectodomain Deterioration while Possessing an Impressive Cytoplasmic Tail Motif.