O-GlcNAcylation and Cancer / / edited by Ikram El Yazidi-Belkoura and Tony Lefebvre.
This book gathers reviews and articles on the role of O-GlcNAcylation in cancer underlying the pharmacological targeting of the O-GlcNAcylation enzymes OGT and OGA as a promising anticancer strategy. Particular attention is paid to the involvement of O-GlcNAcylation in the regulation of transcriptio...
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Place / Publishing House: | Basel : : MDPI - Multidisciplinary Digital Publishing Institute,, 2022. |
Year of Publication: | 2022 |
Language: | English |
Physical Description: | 1 online resource (112 pages) |
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O-GlcNAcylation and Cancer / edited by Ikram El Yazidi-Belkoura and Tony Lefebvre. Basel : MDPI - Multidisciplinary Digital Publishing Institute, 2022. 1 online resource (112 pages) text txt rdacontent computer c rdamedia online resource cr rdacarrier Description based on publisher supplied metadata and other sources. This book gathers reviews and articles on the role of O-GlcNAcylation in cancer underlying the pharmacological targeting of the O-GlcNAcylation enzymes OGT and OGA as a promising anticancer strategy. Particular attention is paid to the involvement of O-GlcNAcylation in the regulation of transcription and as a link between nutrition and epigenetic dynamics or cellular energy metabolism. The role of O-GlcNAcylation in metastasis, immune responses, and resistance to chemotherapeutic agents is also discussed. 1. Introduction -- 2. O-GlcNAcylation -- 2.2. Functions of O-GlcNAcylation -- 3. O-GlcNAcylation and Cancer -- 3.1. O-GlcNAcylation and Metastasis -- 3.2. O-GlcNAcylation and Receptor Tyrosine Kinase -- 3.3. O-GlcNAcylation and Resistance to Chemotherapy -- 3.4. O-GlcNAcylation as Prognostic Marker -- 4. O-GlcNAcylation and Immune Responses in Cancer -- 4.1. Overview of Immune System and O-GlcNAcylation -- 4.2. T Cell Activation and Differentiation Regulated by O-GlcNAcylation -- 4.3. Macrophage Differentiation and Activation by O-GlcNAcylation -- 4.4. O-GlcNAcylation and Tumor Microenvironment -- 5. Cancer Therapeutics Targeting O-GlcNAcylation -- 6. Conclusions and Future Perspectives -- Author Contributions -- Funding -- Conflicts of Interest -- Footnotes -- References. Glycosylation. 3-0365-3082-7 Yazidi-Belkoura, Ikram El, editor. Lefebvre, Tony, editor. |
language |
English |
format |
eBook |
author2 |
Yazidi-Belkoura, Ikram El, Lefebvre, Tony, |
author_facet |
Yazidi-Belkoura, Ikram El, Lefebvre, Tony, |
author2_variant |
i e y b iey ieyb t l tl |
author2_role |
TeilnehmendeR TeilnehmendeR |
title |
O-GlcNAcylation and Cancer / |
spellingShingle |
O-GlcNAcylation and Cancer / 1. Introduction -- 2. O-GlcNAcylation -- 2.2. Functions of O-GlcNAcylation -- 3. O-GlcNAcylation and Cancer -- 3.1. O-GlcNAcylation and Metastasis -- 3.2. O-GlcNAcylation and Receptor Tyrosine Kinase -- 3.3. O-GlcNAcylation and Resistance to Chemotherapy -- 3.4. O-GlcNAcylation as Prognostic Marker -- 4. O-GlcNAcylation and Immune Responses in Cancer -- 4.1. Overview of Immune System and O-GlcNAcylation -- 4.2. T Cell Activation and Differentiation Regulated by O-GlcNAcylation -- 4.3. Macrophage Differentiation and Activation by O-GlcNAcylation -- 4.4. O-GlcNAcylation and Tumor Microenvironment -- 5. Cancer Therapeutics Targeting O-GlcNAcylation -- 6. Conclusions and Future Perspectives -- Author Contributions -- Funding -- Conflicts of Interest -- Footnotes -- References. |
title_full |
O-GlcNAcylation and Cancer / edited by Ikram El Yazidi-Belkoura and Tony Lefebvre. |
title_fullStr |
O-GlcNAcylation and Cancer / edited by Ikram El Yazidi-Belkoura and Tony Lefebvre. |
title_full_unstemmed |
O-GlcNAcylation and Cancer / edited by Ikram El Yazidi-Belkoura and Tony Lefebvre. |
title_auth |
O-GlcNAcylation and Cancer / |
title_new |
O-GlcNAcylation and Cancer / |
title_sort |
o-glcnacylation and cancer / |
publisher |
MDPI - Multidisciplinary Digital Publishing Institute, |
publishDate |
2022 |
physical |
1 online resource (112 pages) |
contents |
1. Introduction -- 2. O-GlcNAcylation -- 2.2. Functions of O-GlcNAcylation -- 3. O-GlcNAcylation and Cancer -- 3.1. O-GlcNAcylation and Metastasis -- 3.2. O-GlcNAcylation and Receptor Tyrosine Kinase -- 3.3. O-GlcNAcylation and Resistance to Chemotherapy -- 3.4. O-GlcNAcylation as Prognostic Marker -- 4. O-GlcNAcylation and Immune Responses in Cancer -- 4.1. Overview of Immune System and O-GlcNAcylation -- 4.2. T Cell Activation and Differentiation Regulated by O-GlcNAcylation -- 4.3. Macrophage Differentiation and Activation by O-GlcNAcylation -- 4.4. O-GlcNAcylation and Tumor Microenvironment -- 5. Cancer Therapeutics Targeting O-GlcNAcylation -- 6. Conclusions and Future Perspectives -- Author Contributions -- Funding -- Conflicts of Interest -- Footnotes -- References. |
isbn |
3-0365-3082-7 |
callnumber-first |
Q - Science |
callnumber-subject |
QP - Physiology |
callnumber-label |
QP552 |
callnumber-sort |
QP 3552 G59 O453 42022 |
illustrated |
Not Illustrated |
dewey-hundreds |
500 - Science |
dewey-tens |
570 - Life sciences; biology |
dewey-ones |
572 - Biochemistry |
dewey-full |
572.68 |
dewey-sort |
3572.68 |
dewey-raw |
572.68 |
dewey-search |
572.68 |
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