DNA Replication Controls / / edited by Eishi Noguchi.
The conditions for DNA replication are not ideal, owing to endogenous and exogenous replication stresses that lead to arrest of the replication fork. Arrested forks are among the most serious threats to genomic integrity because they can break or rearrange, leading to genomic instability, which is a...
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| Place / Publishing House: | Basel, Switzerland : : MDPI - Multidisciplinary Digital Publishing Institute,, 2017. |
| Year of Publication: | 2017 |
| Language: | English |
| Physical Description: | 1 online resource (x, 304 pages) |
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| Summary: | The conditions for DNA replication are not ideal, owing to endogenous and exogenous replication stresses that lead to arrest of the replication fork. Arrested forks are among the most serious threats to genomic integrity because they can break or rearrange, leading to genomic instability, which is a hallmark of cancers and aging-related disorders. |
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| Hierarchical level: | Monograph |
| Statement of Responsibility: | edited by Eishi Noguchi. |