Enhancing Mesenchymal Stem Cells (MSCs) for Therapeutic Purposes
The regenerative and immunomodulatory properties of mesenchymal stem cells (MSCs) have made these cells the focus of multiple pre-clinical studies and clinical trials. While the results from these clinical studies have established that MSCs are safe, the efficacy of these cells is not as well-establ...
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| Year of Publication: | 2022 |
| Language: | English |
| Physical Description: | 1 electronic resource (204 p.) |
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Ylostalo, Joni H. edt Enhancing Mesenchymal Stem Cells (MSCs) for Therapeutic Purposes Enhancing Mesenchymal Stem Cells Basel MDPI Books 2022 1 electronic resource (204 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier The regenerative and immunomodulatory properties of mesenchymal stem cells (MSCs) have made these cells the focus of multiple pre-clinical studies and clinical trials. While the results from these clinical studies have established that MSCs are safe, the efficacy of these cells is not as well-established. In this regard, there have been increased efforts towards generating potentiated/activated MSCs with enhanced therapeutic efficacy. Research on the mechanisms for enhancing MSC potency and efficacy is an area of active study with great potential for translation into clinical settings. The purpose of this book is to bring together recent research from a broad range of topics relating to potentiation strategies for enhancing MSC therapeutic efficacy, including growth factor pre-conditioning, hypoxia, and 3D culture. The research compiled in this book increases the basic understanding of MSC culture techniques and describes some MSC preparations for potential novel therapeutic applications. English Medicine bicssc cell therapy immunomodulation polyunsaturated fatty acid CD206 phagocytosis mesenchymal stem cells Vadadustat AKB-6548 preconditioning priming secretome chemotaxis Wharton’s jelly mesenchymal stem cells umbilical cord oxygen conditions secretory profile neuroprotection mesenchymal stromal cells 3D culture neurospheres spheroids pluripotency neural quiescence mesothelioma malignant pleural mesothelioma (MPM) liver cirrhosis placenta-derived mesenchymal stem cells WKYMVm combination therapy iPSC-derived MSCs iMSC secretome pre-conditioning angiogenesis IFN-γ hypoxia potentiation of iMSC efficacy nanofiber-hydrogel composite spinal cord injury inflammation macrophages secondary injury astrocytes axon growth adipose tissue-derived stem cells (ASCs) autophagy rapamycin 3-methyladenine immunosuppression exosome engineered cardiac patches adipose-derived stem cell paracrine potential osteogenic differentiation hepatocyte growth factor fibroblast growth factor 2 3-0365-4996-X 3-0365-4995-1 Durand, Nisha C. edt Ylostalo, Joni H. oth Durand, Nisha C. oth |
| language |
English |
| format |
eBook |
| author2 |
Durand, Nisha C. Ylostalo, Joni H. Durand, Nisha C. |
| author_facet |
Durand, Nisha C. Ylostalo, Joni H. Durand, Nisha C. |
| author2_variant |
j h y jh jhy n c d nc ncd |
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HerausgeberIn Sonstige Sonstige |
| title |
Enhancing Mesenchymal Stem Cells (MSCs) for Therapeutic Purposes |
| spellingShingle |
Enhancing Mesenchymal Stem Cells (MSCs) for Therapeutic Purposes |
| title_full |
Enhancing Mesenchymal Stem Cells (MSCs) for Therapeutic Purposes |
| title_fullStr |
Enhancing Mesenchymal Stem Cells (MSCs) for Therapeutic Purposes |
| title_full_unstemmed |
Enhancing Mesenchymal Stem Cells (MSCs) for Therapeutic Purposes |
| title_auth |
Enhancing Mesenchymal Stem Cells (MSCs) for Therapeutic Purposes |
| title_alt |
Enhancing Mesenchymal Stem Cells |
| title_new |
Enhancing Mesenchymal Stem Cells (MSCs) for Therapeutic Purposes |
| title_sort |
enhancing mesenchymal stem cells (mscs) for therapeutic purposes |
| publisher |
MDPI Books |
| publishDate |
2022 |
| physical |
1 electronic resource (204 p.) |
| isbn |
3-0365-4996-X 3-0365-4995-1 |
| illustrated |
Not Illustrated |
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Enhancing Mesenchymal Stem Cells (MSCs) for Therapeutic Purposes |
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