Leaders in Cardiovascular Research: A Special Issue Dedicated to Professor Adriana Gittenberger-De Groot
The arterial pole is one of the most complex parts of the heart both in development and disease. It involves the collaboration and orchestration of contributions from the first and second heart fields as well as the neural crest. The precursor cells differentiate into endocardial cushions and putati...
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| Year of Publication: | 2022 |
| Language: | English |
| Physical Description: | 1 electronic resource (372 p.) |
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Jongbloed, Monique edt Leaders in Cardiovascular Research: A Special Issue Dedicated to Professor Adriana Gittenberger-De Groot Leaders in Cardiovascular Research Basel MDPI - Multidisciplinary Digital Publishing Institute 2022 1 electronic resource (372 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier The arterial pole is one of the most complex parts of the heart both in development and disease. It involves the collaboration and orchestration of contributions from the first and second heart fields as well as the neural crest. The precursor cells differentiate into endocardial cushions and putative cardiac valves, the myocardium, and epicardium of the heart, but also into the different layers of the main arterial vessels. These include not only the aorta and the pulmonary trunk but also the pulmonary and coronary arteries, and during development, the arterial duct. Many transcriptional and signaling networks act in timely concert to acquire the proper asymmetric development and function and pressure and flow dynamics. This is not only a human or even mammalian ‘enterprise,’ but is also taking place in so-called ancestral forms from fish to reptiles, including birds. In humans, it is small wonder that many clinical syndromes may arise when something in this complexity is amiss. This Special Issue of JCDD contains contributions focussed on the heart fields, congenital cardiac malformations and associated syndromes, with special emphasis on the cardiac outflow tract. The Issue is devoted to Prof. Dr. Adriana Gittenberger-de Groot, who dedicated her extensive career to research on cardiovascular development. English Public health & preventive medicine bicssc transforming growth factor beta-3 cardiac development loeys dietz syndrome-5 arrhythmogenic right ventricular dysplasia rienhoff syndrome cleft palate congenital heart disease outflow tract septation signaling networks transcription factor AP-2α cardiovascular development outflow tract pharyngeal arch artery neural crest cell pharyngeal ectoderm Tetralogy of Fallot monozygotic twins discordant phenotype genetics variations epigenetics DNA methylation candidate genes acute aortic syndrome cardiovascular disease aorta aortic valve replacement surgical aortic surgery bicuspid aortic valve Bentall Kommerell’s diverticulum right sided aortic arch anomalous left subclavian artery arteria lusoria tracheal compression esophageal compression transposition great arteries coronary anatomy Rac1 proliferation cell polarity congenital heart defects compact myocardium trabeculation aortic stenosis asymptomatic early surgery watchful waiting cardiac progenitor cells second heart field neural crest endocardium cushion valve ductus arteriosus neointima tunica media transcriptome lineage tracing developmental biology cell identity atrioventricular valve epicardium lateral cushion major cushion myxomatous degeneration homograft semilunar valves aortic regurgitation superimposed tissue original leaflet myofibroblasts free edge folding remodeling dissection of ductus arteriosus sudden unexpected intrauterine death single coronary artery Leiden Convention coronary coding system Lipton classification coronary artery anatomy transposition of the great arteries arterial switch operation coronary artery coronary complications imaging fetal aortic stenosis prenatal ultrasound postmortem histology speckle tracking analysis endocardial fibro-elastosis endocardial cushions cartilage foramen of Panizza left aorta right aorta pulmonary trunk pharyngeal arch arteries coronary arteries cardiac fields cardiomyocyte progenitor specification heart tube aortic wall cardiovascular pathogenesis arterial duct 3-0365-4047-4 3-0365-4048-2 Poelmann, Robert edt Jongbloed, Monique oth Poelmann, Robert oth |
| language |
English |
| format |
eBook |
| author2 |
Poelmann, Robert Jongbloed, Monique Poelmann, Robert |
| author_facet |
Poelmann, Robert Jongbloed, Monique Poelmann, Robert |
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m j mj r p rp |
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HerausgeberIn Sonstige Sonstige |
| title |
Leaders in Cardiovascular Research: A Special Issue Dedicated to Professor Adriana Gittenberger-De Groot |
| spellingShingle |
Leaders in Cardiovascular Research: A Special Issue Dedicated to Professor Adriana Gittenberger-De Groot |
| title_full |
Leaders in Cardiovascular Research: A Special Issue Dedicated to Professor Adriana Gittenberger-De Groot |
| title_fullStr |
Leaders in Cardiovascular Research: A Special Issue Dedicated to Professor Adriana Gittenberger-De Groot |
| title_full_unstemmed |
Leaders in Cardiovascular Research: A Special Issue Dedicated to Professor Adriana Gittenberger-De Groot |
| title_auth |
Leaders in Cardiovascular Research: A Special Issue Dedicated to Professor Adriana Gittenberger-De Groot |
| title_alt |
Leaders in Cardiovascular Research |
| title_new |
Leaders in Cardiovascular Research: A Special Issue Dedicated to Professor Adriana Gittenberger-De Groot |
| title_sort |
leaders in cardiovascular research: a special issue dedicated to professor adriana gittenberger-de groot |
| publisher |
MDPI - Multidisciplinary Digital Publishing Institute |
| publishDate |
2022 |
| physical |
1 electronic resource (372 p.) |
| isbn |
3-0365-4047-4 3-0365-4048-2 |
| illustrated |
Not Illustrated |
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Leaders in Cardiovascular Research: A Special Issue Dedicated to Professor Adriana Gittenberger-De Groot |
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