Recent Progress in Solid Dispersion Technology

Amorphous solid dispersion (ASD) is a powerful formulation technology to improve oral absorption of poorly soluble drugs. Despite their being in existence for more than half a century, controlling ASD performance is still regarded as difficult because of ASD’s natural non-equilibrium. However, recen...

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Year of Publication:2019
Language:English
Physical Description:1 electronic resource (204 p.)
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520 |a Amorphous solid dispersion (ASD) is a powerful formulation technology to improve oral absorption of poorly soluble drugs. Despite their being in existence for more than half a century, controlling ASD performance is still regarded as difficult because of ASD’s natural non-equilibrium. However, recent significant advances in ASD knowledge and technology may enable a much broader use of ASD technology. This Special Issue, which includes 3 reviews and 6 original articles, focuses on recent progresses in ASD technology in hopes of helping to accelerate developmental studies in the pharmaceutical industry. In striving for a deep understanding of ASD non-equilibrium behavior, the Special issue also delves into and makes progress in the theory of soft-matter dynamics. 
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653 |a molecular dynamics simulation 
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653 |a bicaludamide 
653 |a phase diagram 
653 |a Weibull dissolution model 
653 |a spectroscopic techniques 
653 |a anticancer drugs 
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653 |a nucleation 
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653 |a enrofloxacin 
653 |a accelerated stability test 
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653 |a tadalafil 
653 |a process development 
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653 |a Wood’s apparatus 
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653 |a solid dispersions 
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653 |a solid dispersion 
653 |a interaction 
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