Mitochondrial Dysfunction in Aging and Diseases of Aging

Mitochondrial Dysfunction in Aging and Diseases of Aging

This collection of review articles authored by international experts pulls together current information about the role of mitochondria in aging and diseases of aging. Mitochondria are vitally important cellular organelles and undergo their own aging process becoming less efficient in aged animals in...

Full description

Saved in:
Bibliographic Details
:
Haas, Richard H.
Year of Publication:2019
Language:English
Physical Description:1 electronic resource (270 p.)
Tags: Add Tag
No Tags, Be the first to tag this record!
id 993548369204498
ctrlnum (CKB)4100000010106154
(oapen)https://directory.doabooks.org/handle/20.500.12854/53609
(EXLCZ)994100000010106154
collection bib_alma
record_format marc
spelling Haas, Richard H. auth
Mitochondrial Dysfunction in Aging and Diseases of Aging
MDPI - Multidisciplinary Digital Publishing Institute 2019
1 electronic resource (270 p.)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
This collection of review articles authored by international experts pulls together current information about the role of mitochondria in aging and diseases of aging. Mitochondria are vitally important cellular organelles and undergo their own aging process becoming less efficient in aged animals including humans. These changes have wide-ranging significance contributing to immune dysfunction (autoimmunity and immune deficiency), inflammation, delayed healing, skin and retinal damage, cancer and most of the degenerative diseases of aging. Mitochondrial aging predisposes to drug toxicity in the geriatric population and to many of the features of normal aging. The research detailed in this book summarizes current understanding of the role of mitochondria in the complex molecular changes of aging, moving on to specific diseases of aging. Mitochondrial dysfunction is an important target for development of treatments for aging and disease. The last article details how exercise is a treatment and combats many features of the aging process.
English
age-related diseases
sphingolipids
glaucoma
ALS
neurodegeneration
mitochondrial dysfunction
adaptive immunity
senescence
de-emergence
innate immunity
cell danger response
mitochondrial transfer
axonal transport
cytokines
mitochondrial
age-related macular degeneration
prevention
heart failure
purinergic signaling
autophagy
Alzheimer's disease
diabetic retinopathy
proteostasis
1
immunosenescence
Miro1
ROS
metabolism
optic nerve
polypharmacy
eIF2?
Parkin
coenzyme Q10
neurodegenerative disease
DNA damage
skin
exercise
nucleotide metabolism
pasteur effect
stress response
inflammation
retina
drug-induced mitochondrial toxicity
neuroinflammation
exosomes
reactive oxygen species
25(OH)D
cardiomyopathy
crabtree effect
insulin resistance
cardiovascular disease
ageing
genetic mutations
metabokines
mitochondria
multiple sclerosis
aerobic
healing cycle
SOD1
mitophagy
PINK1
type 2 diabetes
integrated cell stress response
morbidity and mortality
ultraviolet
photoageing
cancer
aging
25(OH)2D
lysosome
NAD+
Parkinson's disease
3-03921-327-X
language English
format eBook
author Haas, Richard H.
spellingShingle Haas, Richard H.
Mitochondrial Dysfunction in Aging and Diseases of Aging
author_facet Haas, Richard H.
author_variant r h h rh rhh
author_sort Haas, Richard H.
title Mitochondrial Dysfunction in Aging and Diseases of Aging
title_full Mitochondrial Dysfunction in Aging and Diseases of Aging
title_fullStr Mitochondrial Dysfunction in Aging and Diseases of Aging
title_full_unstemmed Mitochondrial Dysfunction in Aging and Diseases of Aging
title_auth Mitochondrial Dysfunction in Aging and Diseases of Aging
title_new Mitochondrial Dysfunction in Aging and Diseases of Aging
title_sort mitochondrial dysfunction in aging and diseases of aging
publisher MDPI - Multidisciplinary Digital Publishing Institute
publishDate 2019
physical 1 electronic resource (270 p.)
isbn 3-03921-328-8
3-03921-327-X
illustrated Not Illustrated
work_keys_str_mv AT haasrichardh mitochondrialdysfunctioninaginganddiseasesofaging
status_str n
ids_txt_mv (CKB)4100000010106154
(oapen)https://directory.doabooks.org/handle/20.500.12854/53609
(EXLCZ)994100000010106154
carrierType_str_mv cr
is_hierarchy_title Mitochondrial Dysfunction in Aging and Diseases of Aging
_version_ 1787551963021312001
fullrecord <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>04042nam-a2201129z--4500</leader><controlfield tag="001">993548369204498</controlfield><controlfield tag="005">20231214133050.0</controlfield><controlfield tag="006">m o d </controlfield><controlfield tag="007">cr|mn|---annan</controlfield><controlfield tag="008">202102s2019 xx |||||o ||| 0|eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">3-03921-328-8</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(CKB)4100000010106154</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(oapen)https://directory.doabooks.org/handle/20.500.12854/53609</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(EXLCZ)994100000010106154</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Haas, Richard H.</subfield><subfield code="4">auth</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Mitochondrial Dysfunction in Aging and Diseases of Aging</subfield></datafield><datafield tag="260" ind1=" " ind2=" "><subfield code="b">MDPI - Multidisciplinary Digital Publishing Institute</subfield><subfield code="c">2019</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 electronic resource (270 p.)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">computer</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">online resource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">This collection of review articles authored by international experts pulls together current information about the role of mitochondria in aging and diseases of aging. Mitochondria are vitally important cellular organelles and undergo their own aging process becoming less efficient in aged animals including humans. These changes have wide-ranging significance contributing to immune dysfunction (autoimmunity and immune deficiency), inflammation, delayed healing, skin and retinal damage, cancer and most of the degenerative diseases of aging. Mitochondrial aging predisposes to drug toxicity in the geriatric population and to many of the features of normal aging. The research detailed in this book summarizes current understanding of the role of mitochondria in the complex molecular changes of aging, moving on to specific diseases of aging. Mitochondrial dysfunction is an important target for development of treatments for aging and disease. The last article details how exercise is a treatment and combats many features of the aging process.</subfield></datafield><datafield tag="546" ind1=" " ind2=" "><subfield code="a">English</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">age-related diseases</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">sphingolipids</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">glaucoma</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ALS</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">neurodegeneration</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mitochondrial dysfunction</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">adaptive immunity</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">senescence</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">de-emergence</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">innate immunity</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cell danger response</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mitochondrial transfer</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">axonal transport</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cytokines</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mitochondrial</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">age-related macular degeneration</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">prevention</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">heart failure</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">purinergic signaling</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">autophagy</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Alzheimer's disease</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">diabetic retinopathy</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">proteostasis</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">1</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">immunosenescence</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Miro1</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ROS</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">metabolism</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">optic nerve</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">polypharmacy</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">eIF2?</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Parkin</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">coenzyme Q10</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">neurodegenerative disease</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">DNA damage</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">skin</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">exercise</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">nucleotide metabolism</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">pasteur effect</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">stress response</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">inflammation</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">retina</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">drug-induced mitochondrial toxicity</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">neuroinflammation</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">exosomes</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">reactive oxygen species</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">25(OH)D</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cardiomyopathy</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">crabtree effect</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">insulin resistance</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cardiovascular disease</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ageing</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">genetic mutations</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">metabokines</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mitochondria</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">multiple sclerosis</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">aerobic</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">healing cycle</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">SOD1</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mitophagy</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">PINK1</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">type 2 diabetes</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">integrated cell stress response</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">morbidity and mortality</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ultraviolet</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">photoageing</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cancer</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">aging</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">25(OH)2D</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">lysosome</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">NAD+</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Parkinson's disease</subfield></datafield><datafield tag="776" ind1=" " ind2=" "><subfield code="z">3-03921-327-X</subfield></datafield><datafield tag="906" ind1=" " ind2=" "><subfield code="a">BOOK</subfield></datafield><datafield tag="ADM" ind1=" " ind2=" "><subfield code="b">2023-12-15 05:41:36 Europe/Vienna</subfield><subfield code="f">system</subfield><subfield code="c">marc21</subfield><subfield code="a">2020-02-01 22:26:53 Europe/Vienna</subfield><subfield code="g">false</subfield></datafield><datafield tag="AVE" ind1=" " ind2=" "><subfield code="i">DOAB Directory of Open Access Books</subfield><subfield code="P">DOAB Directory of Open Access Books</subfield><subfield code="x">https://eu02.alma.exlibrisgroup.com/view/uresolver/43ACC_OEAW/openurl?u.ignore_date_coverage=true&amp;portfolio_pid=5338793260004498&amp;Force_direct=true</subfield><subfield code="Z">5338793260004498</subfield><subfield code="b">Available</subfield><subfield code="8">5338793260004498</subfield></datafield></record></collection>

Similar Items