Improving outcomes in cerebral palsy with early intervention : : new translational approaches / / topic editors, Anna Purna Basu and Gavin Clowry.
The aim of this Research Topic was to collate articles describing prediction of outcomes of pre- and perinatal lesions leading to cerebral palsy, basic research in animal models and human subjects, and ideas for, and trials of, interventions in the first two years of life.CP arises from insults to t...
Saved in:
: | |
---|---|
TeilnehmendeR: | |
Place / Publishing House: | [Lausanne, Switzerland] : : Frontiers Media SA,, 2015. |
Year of Publication: | 2015 |
Language: | English |
Series: | Frontiers Research Topics,
|
Physical Description: | 1 online resource (155 pages). |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
993548306804498 |
---|---|
ctrlnum |
(CKB)3710000000520112 (WaSeSS)IndRDA00058916 (oapen)https://directory.doabooks.org/handle/20.500.12854/50066 (EXLCZ)993710000000520112 |
collection |
bib_alma |
record_format |
marc |
spelling |
Anna Purna Basu auth Improving outcomes in cerebral palsy with early intervention : new translational approaches / topic editors, Anna Purna Basu and Gavin Clowry. Frontiers Media SA 2015 [Lausanne, Switzerland] : Frontiers Media SA, 2015. 1 online resource (155 pages). text txt rdacontent computer c rdamedia online resource cr rdacarrier Frontiers Research Topics, 1664-8714 Includes bibliographical references. Description based on: online resource; title from pdf title page (frontiers, viewed Jul. 13, 2016). The aim of this Research Topic was to collate articles describing prediction of outcomes of pre- and perinatal lesions leading to cerebral palsy, basic research in animal models and human subjects, and ideas for, and trials of, interventions in the first two years of life.CP arises from insults to the sensorimotor cortex, subcortical axon tracts and subplate. The aetiology is complex and often multifactorial. The outcome is not simply a loss of voluntary control due to disruption of descending pathways, but also involves abnormal development of reflex and corticospinal circuitry. CP may be viewed as aberrant plasticity in response to a lesion, indeed, abnormalities in movement are subtle at first but develop subsequently. It is misleading to suppose that developmental mechanisms are self-reparative. The challenge is to understand activitydependent fine tuning of neural circuitry during normal development and to find how to promote desirable plasticity whilst limiting undesirable effects following developmental lesions. However, before proposing interventions, we have to develop our ability to predict the severity of neonatal insults.We solicited a variety of articles, including long and short reviews, original research and opinion pieces, from both basic scientists and clinicians. Likewise we, as editors, have complementary knowledge and experience in this area. Anna Basu is an academic pediatric neurologist and Gavin Clowry is a developmental neuroscientist. English Cerebral palsy. outcome prediction Early Intervention Translational Medical Research diagnosis Cerebral Palsy 2-88919-512-0 Basu, Anna Purna, editor. Clowry, Gavin, editor. |
language |
English |
format |
eBook |
author |
Anna Purna Basu |
spellingShingle |
Anna Purna Basu Improving outcomes in cerebral palsy with early intervention : new translational approaches / Frontiers Research Topics, |
author_facet |
Anna Purna Basu Basu, Anna Purna, Clowry, Gavin, |
author_variant |
a p b apb |
author2 |
Basu, Anna Purna, Clowry, Gavin, |
author2_variant |
a p b ap apb g c gc |
author2_role |
TeilnehmendeR TeilnehmendeR |
author_sort |
Anna Purna Basu |
title |
Improving outcomes in cerebral palsy with early intervention : new translational approaches / |
title_sub |
new translational approaches / |
title_full |
Improving outcomes in cerebral palsy with early intervention : new translational approaches / topic editors, Anna Purna Basu and Gavin Clowry. |
title_fullStr |
Improving outcomes in cerebral palsy with early intervention : new translational approaches / topic editors, Anna Purna Basu and Gavin Clowry. |
title_full_unstemmed |
Improving outcomes in cerebral palsy with early intervention : new translational approaches / topic editors, Anna Purna Basu and Gavin Clowry. |
title_auth |
Improving outcomes in cerebral palsy with early intervention : new translational approaches / |
title_new |
Improving outcomes in cerebral palsy with early intervention : |
title_sort |
improving outcomes in cerebral palsy with early intervention : new translational approaches / |
series |
Frontiers Research Topics, |
series2 |
Frontiers Research Topics, |
publisher |
Frontiers Media SA Frontiers Media SA, |
publishDate |
2015 |
physical |
1 online resource (155 pages). |
isbn |
2-88919-512-0 |
issn |
1664-8714 |
callnumber-first |
R - Medicine |
callnumber-subject |
RC - Internal Medicine |
callnumber-label |
RC388 |
callnumber-sort |
RC 3388 |
illustrated |
Not Illustrated |
work_keys_str_mv |
AT annapurnabasu improvingoutcomesincerebralpalsywithearlyinterventionnewtranslationalapproaches AT basuannapurna improvingoutcomesincerebralpalsywithearlyinterventionnewtranslationalapproaches AT clowrygavin improvingoutcomesincerebralpalsywithearlyinterventionnewtranslationalapproaches |
status_str |
n |
ids_txt_mv |
(CKB)3710000000520112 (WaSeSS)IndRDA00058916 (oapen)https://directory.doabooks.org/handle/20.500.12854/50066 (EXLCZ)993710000000520112 |
carrierType_str_mv |
cr |
is_hierarchy_title |
Improving outcomes in cerebral palsy with early intervention : new translational approaches / |
author2_original_writing_str_mv |
noLinkedField noLinkedField |
_version_ |
1796648768256344064 |
fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01443nam a2200313 i 4500</leader><controlfield tag="001">993548306804498</controlfield><controlfield tag="005">20160713092751.0</controlfield><controlfield tag="006">m o u </controlfield><controlfield tag="007">cr |||||||||||</controlfield><controlfield tag="008">160713s2015 sz |||||o|||||||||||eng d</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(CKB)3710000000520112</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(WaSeSS)IndRDA00058916</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(oapen)https://directory.doabooks.org/handle/20.500.12854/50066</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(EXLCZ)993710000000520112</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">WaSeSS</subfield><subfield code="b">eng</subfield><subfield code="e">rda</subfield><subfield code="c">WaSeSS</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="4"><subfield code="a">RC388</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Anna Purna Basu</subfield><subfield code="4">auth</subfield></datafield><datafield tag="245" ind1="0" ind2="0"><subfield code="a">Improving outcomes in cerebral palsy with early intervention :</subfield><subfield code="b">new translational approaches /</subfield><subfield code="c">topic editors, Anna Purna Basu and Gavin Clowry.</subfield></datafield><datafield tag="260" ind1=" " ind2=" "><subfield code="b">Frontiers Media SA</subfield><subfield code="c">2015</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">[Lausanne, Switzerland] :</subfield><subfield code="b">Frontiers Media SA,</subfield><subfield code="c">2015.</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 online resource (155 pages).</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">computer</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">online resource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Frontiers Research Topics,</subfield><subfield code="x">1664-8714</subfield></datafield><datafield tag="504" ind1=" " ind2=" "><subfield code="a">Includes bibliographical references.</subfield></datafield><datafield tag="588" ind1=" " ind2=" "><subfield code="a">Description based on: online resource; title from pdf title page (frontiers, viewed Jul. 13, 2016).</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The aim of this Research Topic was to collate articles describing prediction of outcomes of pre- and perinatal lesions leading to cerebral palsy, basic research in animal models and human subjects, and ideas for, and trials of, interventions in the first two years of life.CP arises from insults to the sensorimotor cortex, subcortical axon tracts and subplate. The aetiology is complex and often multifactorial. The outcome is not simply a loss of voluntary control due to disruption of descending pathways, but also involves abnormal development of reflex and corticospinal circuitry. CP may be viewed as aberrant plasticity in response to a lesion, indeed, abnormalities in movement are subtle at first but develop subsequently. It is misleading to suppose that developmental mechanisms are self-reparative. The challenge is to understand activitydependent fine tuning of neural circuitry during normal development and to find how to promote desirable plasticity whilst limiting undesirable effects following developmental lesions. However, before proposing interventions, we have to develop our ability to predict the severity of neonatal insults.We solicited a variety of articles, including long and short reviews, original research and opinion pieces, from both basic scientists and clinicians. Likewise we, as editors, have complementary knowledge and experience in this area. Anna Basu is an academic pediatric neurologist and Gavin Clowry is a developmental neuroscientist.</subfield></datafield><datafield tag="546" ind1=" " ind2=" "><subfield code="a">English</subfield></datafield><datafield tag="650" ind1=" " ind2="0"><subfield code="a">Cerebral palsy.</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">outcome prediction</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Early Intervention</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Translational Medical Research</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">diagnosis</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Cerebral Palsy</subfield></datafield><datafield tag="776" ind1=" " ind2=" "><subfield code="z">2-88919-512-0</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Basu, Anna Purna,</subfield><subfield code="e">editor.</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Clowry, Gavin,</subfield><subfield code="e">editor.</subfield></datafield><datafield tag="906" ind1=" " ind2=" "><subfield code="a">BOOK</subfield></datafield><datafield tag="ADM" ind1=" " ind2=" "><subfield code="b">2023-02-22 03:34:39 Europe/Vienna</subfield><subfield code="f">system</subfield><subfield code="c">marc21</subfield><subfield code="a">2015-12-12 16:57:58 Europe/Vienna</subfield><subfield code="g">false</subfield></datafield><datafield tag="AVE" ind1=" " ind2=" "><subfield code="i">DOAB Directory of Open Access Books</subfield><subfield code="P">DOAB Directory of Open Access Books</subfield><subfield code="x">https://eu02.alma.exlibrisgroup.com/view/uresolver/43ACC_OEAW/openurl?u.ignore_date_coverage=true&portfolio_pid=5338774590004498&Force_direct=true</subfield><subfield code="Z">5338774590004498</subfield><subfield code="b">Available</subfield><subfield code="8">5338774590004498</subfield></datafield></record></collection> |