Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation
Transcriptional regulation is a critical biological process involved in the response of a cell, a tissue or an organism to a variety of intra- and extra-cellular signals. Besides, it controls the establishment and maintenance of cell identity throughout developmental and differentiation programs. Th...
Saved in:
| : | |
|---|---|
| Year of Publication: | 2019 |
| Language: | English |
| Physical Description: | 1 electronic resource (356 p.) |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| id |
993548223504498 |
|---|---|
| ctrlnum |
(CKB)4920000000094779 (oapen)https://directory.doabooks.org/handle/20.500.12854/61178 (EXLCZ)994920000000094779 |
| collection |
bib_alma |
| record_format |
marc |
| spelling |
Ciccodicola, Alfredo auth Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation Transcriptional Regulation MDPI - Multidisciplinary Digital Publishing Institute 2019 1 electronic resource (356 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier Transcriptional regulation is a critical biological process involved in the response of a cell, a tissue or an organism to a variety of intra- and extra-cellular signals. Besides, it controls the establishment and maintenance of cell identity throughout developmental and differentiation programs. This highly complex and dynamic process is orchestrated by a huge number of molecules and protein networks and occurs through multiple temporal and functional steps. Of note, many human disorders are characterized by misregulation of global transcription since most of the signaling pathways ultimately target components of transcription machinery. This book includes a selection of papers that illustrate recent advances in our understanding of transcriptional regulation and focuses on many important topics, from cis-regulatory elements to transcription factors, chromatin regulators and non-coding RNAs, other than several transcriptome studies and computational analyses. English transcription factor transcription self-incompatibility cytogenetics epigenetics selenocysteine tea AP-2? nonsense-mediated decay transcriptomics Akt1 promoter cell metabolism pediveliger larvae Patau Syndrome tristetraprolin (TTP) long non-coding RNA (lncRNA) pregnancy G-quadruplex glioblastoma placenta PRDM gene family circRNA-disease associations bioadhesive gene expression Crassostrea gigas transcription regulation cell differentiation RNA interference transcriptome inflammatory response FOXO1 Adiponectin liquid chromatograph-tandem mass spectrometer (LC-MS/MS) selenium selenocysteine insertion sequence inflammation selenoproteins research methods nutritional status structures and functions CRISPR/Cas9 fertilization melanin differentially expressed genes tyrosinase posttranscriptional regulation major depressive disorder human malignancies pathway CDKN1C transcription factors p57Kip2 enhancer activity mouse disorders high-throughput RNA sequencing (RNA-Seq) TCGA data analysis RNA-seq heterogeneous network insect and drug design therapeutic targets mechanisms obesity Pacific oyster Rsh regulon common pathway Pax3 somatic mutations nutrition molecular docking bioinformatics interactome long non-coding RNAs transcriptional regulation Pteria penguin (Röding Adiponectin receptors transcriptome profiling 1798) N-acyl-l-homoserine lactone ppGpp tumorigenesis sphingomonads human disease adenosine and uridine-rich elements (AREs) progress and prospects miR-25-3p acute leukemia Novosphingobium pentaromativorans US6-1 microscopy cancer molecular pathways causal inference 3-03921-265-6 Casamassimi, Amelia auth |
| language |
English |
| format |
eBook |
| author |
Ciccodicola, Alfredo |
| spellingShingle |
Ciccodicola, Alfredo Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation |
| author_facet |
Ciccodicola, Alfredo Casamassimi, Amelia |
| author_variant |
a c ac |
| author2 |
Casamassimi, Amelia |
| author2_variant |
a c ac |
| author_sort |
Ciccodicola, Alfredo |
| title |
Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation |
| title_full |
Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation |
| title_fullStr |
Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation |
| title_full_unstemmed |
Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation |
| title_auth |
Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation |
| title_alt |
Transcriptional Regulation |
| title_new |
Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation |
| title_sort |
transcriptional regulation: molecules, involved mechanisms and misregulation |
| publisher |
MDPI - Multidisciplinary Digital Publishing Institute |
| publishDate |
2019 |
| physical |
1 electronic resource (356 p.) |
| isbn |
3-03921-266-4 3-03921-265-6 |
| illustrated |
Not Illustrated |
| work_keys_str_mv |
AT ciccodicolaalfredo transcriptionalregulationmoleculesinvolvedmechanismsandmisregulation AT casamassimiamelia transcriptionalregulationmoleculesinvolvedmechanismsandmisregulation AT ciccodicolaalfredo transcriptionalregulation AT casamassimiamelia transcriptionalregulation |
| status_str |
n |
| ids_txt_mv |
(CKB)4920000000094779 (oapen)https://directory.doabooks.org/handle/20.500.12854/61178 (EXLCZ)994920000000094779 |
| carrierType_str_mv |
cr |
| is_hierarchy_title |
Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation |
| author2_original_writing_str_mv |
noLinkedField |
| _version_ |
1796652168000831488 |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>05018nam-a2201429z--4500</leader><controlfield tag="001">993548223504498</controlfield><controlfield tag="005">20231214133640.0</controlfield><controlfield tag="006">m o d </controlfield><controlfield tag="007">cr|mn|---annan</controlfield><controlfield tag="008">202102s2019 xx |||||o ||| 0|eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">3-03921-266-4</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(CKB)4920000000094779</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(oapen)https://directory.doabooks.org/handle/20.500.12854/61178</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(EXLCZ)994920000000094779</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Ciccodicola, Alfredo</subfield><subfield code="4">auth</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Transcriptional Regulation: Molecules, Involved Mechanisms and Misregulation</subfield></datafield><datafield tag="246" ind1=" " ind2=" "><subfield code="a">Transcriptional Regulation</subfield></datafield><datafield tag="260" ind1=" " ind2=" "><subfield code="b">MDPI - Multidisciplinary Digital Publishing Institute</subfield><subfield code="c">2019</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 electronic resource (356 p.)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">computer</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">online resource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Transcriptional regulation is a critical biological process involved in the response of a cell, a tissue or an organism to a variety of intra- and extra-cellular signals. Besides, it controls the establishment and maintenance of cell identity throughout developmental and differentiation programs. This highly complex and dynamic process is orchestrated by a huge number of molecules and protein networks and occurs through multiple temporal and functional steps. Of note, many human disorders are characterized by misregulation of global transcription since most of the signaling pathways ultimately target components of transcription machinery. This book includes a selection of papers that illustrate recent advances in our understanding of transcriptional regulation and focuses on many important topics, from cis-regulatory elements to transcription factors, chromatin regulators and non-coding RNAs, other than several transcriptome studies and computational analyses.</subfield></datafield><datafield tag="546" ind1=" " ind2=" "><subfield code="a">English</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">transcription factor</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">transcription</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">self-incompatibility</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cytogenetics</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">epigenetics</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">selenocysteine</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">tea</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">AP-2?</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">nonsense-mediated decay</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">transcriptomics</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Akt1</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">promoter</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cell metabolism</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">pediveliger larvae</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Patau Syndrome</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">tristetraprolin (TTP)</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">long non-coding RNA (lncRNA)</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">pregnancy</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">G-quadruplex</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">glioblastoma</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">placenta</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">PRDM gene family</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">circRNA-disease associations</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">bioadhesive</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">gene expression</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Crassostrea gigas</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">transcription regulation</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cell differentiation</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">RNA interference</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">transcriptome</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">inflammatory response</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">FOXO1</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Adiponectin</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">liquid chromatograph-tandem mass spectrometer (LC-MS/MS)</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">selenium</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">selenocysteine insertion sequence</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">inflammation</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">selenoproteins</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">research methods</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">nutritional status</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">structures and functions</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">CRISPR/Cas9</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">fertilization</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">melanin</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">differentially expressed genes</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">tyrosinase</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">posttranscriptional regulation</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">major depressive disorder</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">human malignancies</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">pathway</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">CDKN1C</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">transcription factors</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">p57Kip2</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">enhancer activity</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mouse</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">disorders</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">high-throughput RNA sequencing (RNA-Seq)</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">TCGA data analysis</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">RNA-seq</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">heterogeneous network</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">insect</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">and drug design</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">therapeutic targets</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mechanisms</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">obesity</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Pacific oyster</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Rsh regulon</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">common pathway</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Pax3</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">somatic mutations</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">nutrition</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">molecular docking</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">bioinformatics</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">interactome</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">long non-coding RNAs</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">transcriptional regulation</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Pteria penguin (Röding</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Adiponectin receptors</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">transcriptome profiling</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">1798)</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">N-acyl-l-homoserine lactone</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ppGpp</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">tumorigenesis</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">sphingomonads</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">human</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">disease</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">adenosine and uridine-rich elements (AREs)</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">progress and prospects</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">miR-25-3p</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">acute leukemia</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Novosphingobium pentaromativorans US6-1</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">microscopy</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cancer</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">molecular pathways</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">causal inference</subfield></datafield><datafield tag="776" ind1=" " ind2=" "><subfield code="z">3-03921-265-6</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Casamassimi, Amelia</subfield><subfield code="4">auth</subfield></datafield><datafield tag="906" ind1=" " ind2=" "><subfield code="a">BOOK</subfield></datafield><datafield tag="ADM" ind1=" " ind2=" "><subfield code="b">2024-03-01 01:58:15 Europe/Vienna</subfield><subfield code="f">system</subfield><subfield code="c">marc21</subfield><subfield code="a">2019-11-10 04:18:40 Europe/Vienna</subfield><subfield code="g">false</subfield></datafield><datafield tag="AVE" ind1=" " ind2=" "><subfield code="i">DOAB Directory of Open Access Books</subfield><subfield code="P">DOAB Directory of Open Access Books</subfield><subfield code="x">https://eu02.alma.exlibrisgroup.com/view/uresolver/43ACC_OEAW/openurl?u.ignore_date_coverage=true&portfolio_pid=5338819570004498&Force_direct=true</subfield><subfield code="Z">5338819570004498</subfield><subfield code="b">Available</subfield><subfield code="8">5338819570004498</subfield></datafield></record></collection> |