Systemic Sclerosis : : An Update on the Aberrant Immune System and Clinical Features / / edited by Timothy Radstake.
Systemic sclerosis (SSc), or often referred to as Scleroderma (tight skin), is characterized by an exaggerated formation of collagen fibers in the skin, which leads to fibrosis. Accumulating evidence now points toward three pathological hallmarks that are implicated in Ssc, the order of which has ye...
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Place / Publishing House: | [Place of publication not identified] : : InTech,, 2012. |
Year of Publication: | 2012 |
Language: | English |
Physical Description: | 1 online resource (220 pages) |
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(CKB)3230000000077059 (NjHacI)993230000000077059 (oapen)https://directory.doabooks.org/handle/20.500.12854/65521 (EXLCZ)993230000000077059 |
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Radstake, Timothy edt Systemic Sclerosis : An Update on the Aberrant Immune System and Clinical Features / edited by Timothy Radstake. Systemic sclerosis IntechOpen 2012 [Place of publication not identified] : InTech, 2012. 1 online resource (220 pages) text txt rdacontent computer c rdamedia online resource cr rdacarrier Description based on: online resource; title from PDF information screen (InTech, viewed October 22, 2022). Includes bibliographical references and index. Systemic sclerosis (SSc), or often referred to as Scleroderma (tight skin), is characterized by an exaggerated formation of collagen fibers in the skin, which leads to fibrosis. Accumulating evidence now points toward three pathological hallmarks that are implicated in Ssc, the order of which has yet to be determined: endothelial dysfunction, autoantibody formation, and activation of fibroblasts. This current book provides up-to-date information on the pathogenesis and clinical features of this severe syndrome. It is our hope that this book will aid both clinicians and researchers in dealing with patients with this clinical syndrome. In addition, we hope to shed more light on this rare and severely disabling syndrome, ultimately leading to better research and successful therapeutic targeting. English Immunology. Immunology 953-307-869-3 Radstake, Timothy, editor. |
language |
English |
format |
eBook |
author2 |
Radstake, Timothy, |
author_facet |
Radstake, Timothy, |
author2_variant |
t r tr t r tr |
author2_role |
TeilnehmendeR |
title |
Systemic Sclerosis : An Update on the Aberrant Immune System and Clinical Features / |
spellingShingle |
Systemic Sclerosis : An Update on the Aberrant Immune System and Clinical Features / |
title_sub |
An Update on the Aberrant Immune System and Clinical Features / |
title_full |
Systemic Sclerosis : An Update on the Aberrant Immune System and Clinical Features / edited by Timothy Radstake. |
title_fullStr |
Systemic Sclerosis : An Update on the Aberrant Immune System and Clinical Features / edited by Timothy Radstake. |
title_full_unstemmed |
Systemic Sclerosis : An Update on the Aberrant Immune System and Clinical Features / edited by Timothy Radstake. |
title_auth |
Systemic Sclerosis : An Update on the Aberrant Immune System and Clinical Features / |
title_alt |
Systemic sclerosis |
title_new |
Systemic Sclerosis : |
title_sort |
systemic sclerosis : an update on the aberrant immune system and clinical features / |
publisher |
IntechOpen InTech, |
publishDate |
2012 |
physical |
1 online resource (220 pages) |
isbn |
953-51-6737-5 953-307-869-3 |
callnumber-first |
Q - Science |
callnumber-subject |
QR - Microbiology |
callnumber-label |
QR181 |
callnumber-sort |
QR 3181 S978 42012 |
illustrated |
Not Illustrated |
dewey-hundreds |
600 - Technology |
dewey-tens |
610 - Medicine & health |
dewey-ones |
616 - Diseases |
dewey-full |
616.079 |
dewey-sort |
3616.079 |
dewey-raw |
616.079 |
dewey-search |
616.079 |
work_keys_str_mv |
AT radstaketimothy systemicsclerosisanupdateontheaberrantimmunesystemandclinicalfeatures AT radstaketimothy systemicsclerosis |
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(CKB)3230000000077059 (NjHacI)993230000000077059 (oapen)https://directory.doabooks.org/handle/20.500.12854/65521 (EXLCZ)993230000000077059 |
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Systemic Sclerosis : An Update on the Aberrant Immune System and Clinical Features / |
author2_original_writing_str_mv |
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