Safety Pharmacology - Risk Assessment QT Interval Prolongation and Beyond

Current regulatory guidelines for cardiac safety utilize hERG block and QT interval prolongation as risk markers. This strategy has been successful at preventing harmful drugs from being marketed, but criticized for leading to early withdrawal of potentially safe drugs. Here we collected a series of...

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Superior document:Frontiers Research Topics
:
Year of Publication:2018
Language:English
Series:Frontiers Research Topics
Physical Description:1 electronic resource (385 p.)
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