Advances in Mechanisms of Renal Fibrosis
Scarring of the glomerular and tubulointerstitial compartments is a hallmark of progressive kidney disease. Renal fibrosis involves a complex interplay between kidney cells, leukocytes and fibroblasts in which transforming growth factor-β (TGF-β) plays a key role. This eBook provides a comprehensive...
Saved in:
Superior document: | Frontiers Research Topics |
---|---|
: | |
Year of Publication: | 2018 |
Language: | English |
Series: | Frontiers Research Topics
|
Physical Description: | 1 electronic resource (84 p.) |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
993548039004498 |
---|---|
ctrlnum |
(CKB)4920000000094173 (oapen)https://directory.doabooks.org/handle/20.500.12854/40307 (EXLCZ)994920000000094173 |
collection |
bib_alma |
record_format |
marc |
spelling |
David J. Nikolic-Paterson auth Advances in Mechanisms of Renal Fibrosis Frontiers Media SA 2018 1 electronic resource (84 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier Frontiers Research Topics Scarring of the glomerular and tubulointerstitial compartments is a hallmark of progressive kidney disease. Renal fibrosis involves a complex interplay between kidney cells, leukocytes and fibroblasts in which transforming growth factor-β (TGF-β) plays a key role. This eBook provides a comprehensive update on TGF-β signalling pathways and introduces a range of cellular and molecular mechanisms involved in renal fibrosis both upstream and downstream of TGF-β. The wide variety of potential new targets described herein bodes well for the future development of effective therapies to tackle the major clinical problem of progressive renal fibrosis. English TGF-beta fibroblast JNK miRNA Smad non-classical RAS BMP7 HDAC HIPK2 2-88945-499-1 Hui Y. Lan auth |
language |
English |
format |
eBook |
author |
David J. Nikolic-Paterson |
spellingShingle |
David J. Nikolic-Paterson Advances in Mechanisms of Renal Fibrosis Frontiers Research Topics |
author_facet |
David J. Nikolic-Paterson Hui Y. Lan |
author_variant |
d j n p djnp |
author2 |
Hui Y. Lan |
author2_variant |
h y l hyl |
author_sort |
David J. Nikolic-Paterson |
title |
Advances in Mechanisms of Renal Fibrosis |
title_full |
Advances in Mechanisms of Renal Fibrosis |
title_fullStr |
Advances in Mechanisms of Renal Fibrosis |
title_full_unstemmed |
Advances in Mechanisms of Renal Fibrosis |
title_auth |
Advances in Mechanisms of Renal Fibrosis |
title_new |
Advances in Mechanisms of Renal Fibrosis |
title_sort |
advances in mechanisms of renal fibrosis |
series |
Frontiers Research Topics |
series2 |
Frontiers Research Topics |
publisher |
Frontiers Media SA |
publishDate |
2018 |
physical |
1 electronic resource (84 p.) |
isbn |
2-88945-499-1 |
illustrated |
Not Illustrated |
work_keys_str_mv |
AT davidjnikolicpaterson advancesinmechanismsofrenalfibrosis AT huiylan advancesinmechanismsofrenalfibrosis |
status_str |
n |
ids_txt_mv |
(CKB)4920000000094173 (oapen)https://directory.doabooks.org/handle/20.500.12854/40307 (EXLCZ)994920000000094173 |
carrierType_str_mv |
cr |
hierarchy_parent_title |
Frontiers Research Topics |
is_hierarchy_title |
Advances in Mechanisms of Renal Fibrosis |
container_title |
Frontiers Research Topics |
author2_original_writing_str_mv |
noLinkedField |
_version_ |
1787548435057999872 |
fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01709nam-a2200385z--4500</leader><controlfield tag="001">993548039004498</controlfield><controlfield tag="005">20231214133718.0</controlfield><controlfield tag="006">m o d </controlfield><controlfield tag="007">cr|mn|---annan</controlfield><controlfield tag="008">202102s2018 xx |||||o ||| 0|eng d</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(CKB)4920000000094173</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(oapen)https://directory.doabooks.org/handle/20.500.12854/40307</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(EXLCZ)994920000000094173</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">David J. Nikolic-Paterson</subfield><subfield code="4">auth</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Advances in Mechanisms of Renal Fibrosis</subfield></datafield><datafield tag="260" ind1=" " ind2=" "><subfield code="b">Frontiers Media SA</subfield><subfield code="c">2018</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 electronic resource (84 p.)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">computer</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">online resource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="1" ind2=" "><subfield code="a">Frontiers Research Topics</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Scarring of the glomerular and tubulointerstitial compartments is a hallmark of progressive kidney disease. Renal fibrosis involves a complex interplay between kidney cells, leukocytes and fibroblasts in which transforming growth factor-β (TGF-β) plays a key role. This eBook provides a comprehensive update on TGF-β signalling pathways and introduces a range of cellular and molecular mechanisms involved in renal fibrosis both upstream and downstream of TGF-β. The wide variety of potential new targets described herein bodes well for the future development of effective therapies to tackle the major clinical problem of progressive renal fibrosis.</subfield></datafield><datafield tag="546" ind1=" " ind2=" "><subfield code="a">English</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">TGF-beta</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">fibroblast</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">JNK</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">miRNA</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Smad</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">non-classical RAS</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">BMP7</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">HDAC</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">HIPK2</subfield></datafield><datafield tag="776" ind1=" " ind2=" "><subfield code="z">2-88945-499-1</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Hui Y. Lan</subfield><subfield code="4">auth</subfield></datafield><datafield tag="906" ind1=" " ind2=" "><subfield code="a">BOOK</subfield></datafield><datafield tag="ADM" ind1=" " ind2=" "><subfield code="b">2023-12-15 06:02:55 Europe/Vienna</subfield><subfield code="f">system</subfield><subfield code="c">marc21</subfield><subfield code="a">2019-11-10 04:18:40 Europe/Vienna</subfield><subfield code="g">false</subfield></datafield><datafield tag="AVE" ind1=" " ind2=" "><subfield code="i">DOAB Directory of Open Access Books</subfield><subfield code="P">DOAB Directory of Open Access Books</subfield><subfield code="x">https://eu02.alma.exlibrisgroup.com/view/uresolver/43ACC_OEAW/openurl?u.ignore_date_coverage=true&portfolio_pid=5338754250004498&Force_direct=true</subfield><subfield code="Z">5338754250004498</subfield><subfield code="b">Available</subfield><subfield code="8">5338754250004498</subfield></datafield></record></collection> |