Advances in Mechanisms of Renal Fibrosis

Advances in Mechanisms of Renal Fibrosis

Scarring of the glomerular and tubulointerstitial compartments is a hallmark of progressive kidney disease. Renal fibrosis involves a complex interplay between kidney cells, leukocytes and fibroblasts in which transforming growth factor-β (TGF-β) plays a key role. This eBook provides a comprehensive...

Full description

Saved in:
Bibliographic Details
Superior document:Frontiers Research Topics
:
David J. Nikolic-Paterson
Hui Y. Lan
Year of Publication:2018
Language:English
Series:Frontiers Research Topics
Physical Description:1 electronic resource (84 p.)
Tags: Add Tag
No Tags, Be the first to tag this record!
id 993548039004498
ctrlnum (CKB)4920000000094173
(oapen)https://directory.doabooks.org/handle/20.500.12854/40307
(EXLCZ)994920000000094173
collection bib_alma
record_format marc
spelling David J. Nikolic-Paterson auth
Advances in Mechanisms of Renal Fibrosis
Frontiers Media SA 2018
1 electronic resource (84 p.)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Frontiers Research Topics
Scarring of the glomerular and tubulointerstitial compartments is a hallmark of progressive kidney disease. Renal fibrosis involves a complex interplay between kidney cells, leukocytes and fibroblasts in which transforming growth factor-β (TGF-β) plays a key role. This eBook provides a comprehensive update on TGF-β signalling pathways and introduces a range of cellular and molecular mechanisms involved in renal fibrosis both upstream and downstream of TGF-β. The wide variety of potential new targets described herein bodes well for the future development of effective therapies to tackle the major clinical problem of progressive renal fibrosis.
English
TGF-beta
fibroblast
JNK
miRNA
Smad
non-classical RAS
BMP7
HDAC
HIPK2
2-88945-499-1
Hui Y. Lan auth
language English
format eBook
author David J. Nikolic-Paterson
spellingShingle David J. Nikolic-Paterson
Advances in Mechanisms of Renal Fibrosis
Frontiers Research Topics
author_facet David J. Nikolic-Paterson
Hui Y. Lan
author_variant d j n p djnp
author2 Hui Y. Lan
author2_variant h y l hyl
author_sort David J. Nikolic-Paterson
title Advances in Mechanisms of Renal Fibrosis
title_full Advances in Mechanisms of Renal Fibrosis
title_fullStr Advances in Mechanisms of Renal Fibrosis
title_full_unstemmed Advances in Mechanisms of Renal Fibrosis
title_auth Advances in Mechanisms of Renal Fibrosis
title_new Advances in Mechanisms of Renal Fibrosis
title_sort advances in mechanisms of renal fibrosis
series Frontiers Research Topics
series2 Frontiers Research Topics
publisher Frontiers Media SA
publishDate 2018
physical 1 electronic resource (84 p.)
isbn 2-88945-499-1
illustrated Not Illustrated
work_keys_str_mv AT davidjnikolicpaterson advancesinmechanismsofrenalfibrosis
AT huiylan advancesinmechanismsofrenalfibrosis
status_str n
ids_txt_mv (CKB)4920000000094173
(oapen)https://directory.doabooks.org/handle/20.500.12854/40307
(EXLCZ)994920000000094173
carrierType_str_mv cr
hierarchy_parent_title Frontiers Research Topics
is_hierarchy_title Advances in Mechanisms of Renal Fibrosis
container_title Frontiers Research Topics
author2_original_writing_str_mv noLinkedField
_version_ 1787548435057999872
fullrecord <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01709nam-a2200385z--4500</leader><controlfield tag="001">993548039004498</controlfield><controlfield tag="005">20231214133718.0</controlfield><controlfield tag="006">m o d </controlfield><controlfield tag="007">cr|mn|---annan</controlfield><controlfield tag="008">202102s2018 xx |||||o ||| 0|eng d</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(CKB)4920000000094173</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(oapen)https://directory.doabooks.org/handle/20.500.12854/40307</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(EXLCZ)994920000000094173</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">David J. Nikolic-Paterson</subfield><subfield code="4">auth</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Advances in Mechanisms of Renal Fibrosis</subfield></datafield><datafield tag="260" ind1=" " ind2=" "><subfield code="b">Frontiers Media SA</subfield><subfield code="c">2018</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 electronic resource (84 p.)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">computer</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">online resource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="1" ind2=" "><subfield code="a">Frontiers Research Topics</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Scarring of the glomerular and tubulointerstitial compartments is a hallmark of progressive kidney disease. Renal fibrosis involves a complex interplay between kidney cells, leukocytes and fibroblasts in which transforming growth factor-β (TGF-β) plays a key role. This eBook provides a comprehensive update on TGF-β signalling pathways and introduces a range of cellular and molecular mechanisms involved in renal fibrosis both upstream and downstream of TGF-β. The wide variety of potential new targets described herein bodes well for the future development of effective therapies to tackle the major clinical problem of progressive renal fibrosis.</subfield></datafield><datafield tag="546" ind1=" " ind2=" "><subfield code="a">English</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">TGF-beta</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">fibroblast</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">JNK</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">miRNA</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Smad</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">non-classical RAS</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">BMP7</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">HDAC</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">HIPK2</subfield></datafield><datafield tag="776" ind1=" " ind2=" "><subfield code="z">2-88945-499-1</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Hui Y. Lan</subfield><subfield code="4">auth</subfield></datafield><datafield tag="906" ind1=" " ind2=" "><subfield code="a">BOOK</subfield></datafield><datafield tag="ADM" ind1=" " ind2=" "><subfield code="b">2023-12-15 06:02:55 Europe/Vienna</subfield><subfield code="f">system</subfield><subfield code="c">marc21</subfield><subfield code="a">2019-11-10 04:18:40 Europe/Vienna</subfield><subfield code="g">false</subfield></datafield><datafield tag="AVE" ind1=" " ind2=" "><subfield code="i">DOAB Directory of Open Access Books</subfield><subfield code="P">DOAB Directory of Open Access Books</subfield><subfield code="x">https://eu02.alma.exlibrisgroup.com/view/uresolver/43ACC_OEAW/openurl?u.ignore_date_coverage=true&amp;portfolio_pid=5338754250004498&amp;Force_direct=true</subfield><subfield code="Z">5338754250004498</subfield><subfield code="b">Available</subfield><subfield code="8">5338754250004498</subfield></datafield></record></collection>

Similar Items