Alterations of epigenetics and microRNAs in cancer and cancer stem cell / topic editor: Yoshimasa Saito.

Studies have shown that alterations of epigenetics and microRNAs (miRNAs) play critical roles in the initiation and progression of human cancer. Epigenetic silencing of tumor suppressor genes in cancer cells is generally mediated by DNA hypermethylation of CpG island promoter and histone modificatio...

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Bibliographic Details
Superior document:Frontiers in genetics, volume 4
:
TeilnehmendeR:
Place / Publishing House:[Lausanne, Switzerland] : : Frontiers Media SA,, 2014
Year of Publication:2014
Language:English
Series:Frontiers in genetics ; volume 4.
Physical Description:1 online resource (79 pages) :; illustrations; digital, PDF file(s).
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Table of Contents:
  • Alterations of epigenetics and microRNAs in cancer and cancer stem cell / Yoshimasa Saito
  • Culturing intestinal stem cells: applications for colorectal cancer research / Masayuki Fuji and Toshiro Sato
  • Characterizing the Retinoblastoma 1 locus: putative elements for Rb1 regulation by in silico analysis / Mohammadreza Hajjari, Atefeh Khoshnevisan and Bernardo Lemos
  • Multilayer-omics analyses of human cancers: exploration of biomarkers and drug targets based on the activities of the International Human Epigenome Consortium / Yae Kanai and Eri Arai
  • Non-coding RNAs as epigenetic regulator of glioma stem-like cell differentiation / Keisuke Katsushima and Yutaka Kondo
  • Aberrantly methylated genes in human papillary thyroid cancer and their association with BRAF/RAS mutation / Yasuko Kikuchi, Eiichi Tsuji, Koichi Yagi, Keisuke Matsusaka, Shingo Tsuji, Junichi Kurebayashi, Toshihisa Ogawa, Hiroyuki Aburatani, Atsushi Kaneda
  • MicroRNAs in Barrett's esophagus: future prospects / Juntaro Matsuzaki and Hidekazu Suzuki
  • Epigenetic alteration and microRNA dysregulation in cancer / Hiromu Suzuki, Reo Maruyama, Eiichiro Yamamoto and Masahiro Kai
  • The role of microRNAs in the regulation of cancer stem cells / Ryou-u Takahashi, Hiroaki Miyazaki and Takahiro Ochiya
  • Disruption of the expression and function of microRNAs in lung cancer as a result of epigenetic changes / Kousuke Watanabe and Daiya Takai
  • The role of mesenchymal stem cell in cancer development / Hiroshi Yagi and Yuko Kitagawa.