Etiology, Pathogenesis and Pathophysiology of Aortic Aneurysms and Aneurysm Rupture / / Reinhart Grundmann, editor.
This book considers mainly etiology, pathogenesis, and pathophysiology of aortic aneurysms (AA) and aneurysm rupture and addresses anyone engaged in treatment and prevention of AA. Multiple factors are implicated in AA pathogenesis, and are outlined here in detail by a team of specialist researchers...
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Place / Publishing House: | [Place of publication not identified] : : InTech,, [2011] ©2011 |
Year of Publication: | 2011 |
Language: | English |
Physical Description: | 1 online resource (234 pages) :; illustrations |
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(CKB)3230000000076045 (NjHacI)993230000000076045 (oapen)https://directory.doabooks.org/handle/20.500.12854/65028 (EXLCZ)993230000000076045 |
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Grundmann, Reinhart edt Etiology, Pathogenesis and Pathophysiology of Aortic Aneurysms and Aneurysm Rupture / Reinhart Grundmann, editor. IntechOpen 2011 [Place of publication not identified] : InTech, [2011] ©2011 1 online resource (234 pages) : illustrations text txt rdacontent computer c rdamedia online resource cr rdacarrier Description based on: online resource; title from PDF information screen (InTech, viewed October 19, 2022). Includes bibliographical references and index. This book considers mainly etiology, pathogenesis, and pathophysiology of aortic aneurysms (AA) and aneurysm rupture and addresses anyone engaged in treatment and prevention of AA. Multiple factors are implicated in AA pathogenesis, and are outlined here in detail by a team of specialist researchers. Initial pathological events in AA involve recruitment and infiltration of leukocytes into the aortic adventitia and media, which are associated with the production of inflammatory cytokines, chemokine, and reactive oxygen species. AA development is characterized by elastin fragmentation. As the aorta dilates due to loss of elastin and attenuation of the media, the arterial wall thickens as a result of remodeling. Collagen synthesis increases during the early stages of aneurysm formation, suggesting a repair process, but resulting in a less distensible vessel. Proteases identified in excess in AA and other aortic diseases include matrix metalloproteinases (MMPs), cathepsins, chymase and others. The elucidation of these issues will identify new targets for prophylactic and therapeutic intervention. English Aortic aneurysms. Cardiovascular medicine 953-307-523-6 Grundmann, Reinhart, editor. |
language |
English |
format |
eBook |
author2 |
Grundmann, Reinhart, |
author_facet |
Grundmann, Reinhart, |
author2_variant |
r g rg r g rg |
author2_role |
TeilnehmendeR |
title |
Etiology, Pathogenesis and Pathophysiology of Aortic Aneurysms and Aneurysm Rupture / |
spellingShingle |
Etiology, Pathogenesis and Pathophysiology of Aortic Aneurysms and Aneurysm Rupture / |
title_full |
Etiology, Pathogenesis and Pathophysiology of Aortic Aneurysms and Aneurysm Rupture / Reinhart Grundmann, editor. |
title_fullStr |
Etiology, Pathogenesis and Pathophysiology of Aortic Aneurysms and Aneurysm Rupture / Reinhart Grundmann, editor. |
title_full_unstemmed |
Etiology, Pathogenesis and Pathophysiology of Aortic Aneurysms and Aneurysm Rupture / Reinhart Grundmann, editor. |
title_auth |
Etiology, Pathogenesis and Pathophysiology of Aortic Aneurysms and Aneurysm Rupture / |
title_new |
Etiology, Pathogenesis and Pathophysiology of Aortic Aneurysms and Aneurysm Rupture / |
title_sort |
etiology, pathogenesis and pathophysiology of aortic aneurysms and aneurysm rupture / |
publisher |
IntechOpen InTech, |
publishDate |
2011 |
physical |
1 online resource (234 pages) : illustrations |
isbn |
953-51-6440-6 953-307-523-6 |
callnumber-first |
R - Medicine |
callnumber-subject |
RC - Internal Medicine |
callnumber-label |
RC693 |
callnumber-sort |
RC 3693 E856 42011 |
illustrated |
Illustrated |
dewey-hundreds |
600 - Technology |
dewey-tens |
610 - Medicine & health |
dewey-ones |
616 - Diseases |
dewey-full |
616.133 |
dewey-sort |
3616.133 |
dewey-raw |
616.133 |
dewey-search |
616.133 |
work_keys_str_mv |
AT grundmannreinhart etiologypathogenesisandpathophysiologyofaorticaneurysmsandaneurysmrupture |
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(CKB)3230000000076045 (NjHacI)993230000000076045 (oapen)https://directory.doabooks.org/handle/20.500.12854/65028 (EXLCZ)993230000000076045 |
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is_hierarchy_title |
Etiology, Pathogenesis and Pathophysiology of Aortic Aneurysms and Aneurysm Rupture / |
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