Levodopa-induced dyskinesias in Parkinson's disease : : current knowledge and future scenarios / / topic editors Antonio Cerasa, Giacomo Koch, Alfonso Fasano and Francesca Morgante.
Levodopa-induced dyskinesias (LID) are abnormal movements that occur during the period of maximal benefit of parkinsonian symptoms when levodopa concentration in the brain is highest. LID are mainly choreic in nature and represent a very common problem in up to 80% of Parkinson’s disease (PD) patien...
Saved in:
Superior document: | Frontiers Research Topics |
---|---|
TeilnehmendeR: | |
Place / Publishing House: | France : : Frontiers Media SA,, 2015 |
Year of Publication: | 2015 |
Language: | English |
Series: | Frontiers Research Topics.
|
Physical Description: | 1 online resource (99 pages) :; illustrations; digital file(s). |
Notes: | Bibliographic Level Mode of Issuance: Monograph |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
993547796304498 |
---|---|
ctrlnum |
(CKB)3710000000569647 (SSID)ssj0001679931 (PQKBManifestationID)16490909 (PQKBTitleCode)TC0001679931 (PQKBWorkID)15023518 (PQKB)11088096 (WaSeSS)IndRDA00055886 (EXLCZ)993710000000569647 |
collection |
bib_alma |
record_format |
marc |
spelling |
Levodopa-induced dyskinesias in Parkinson's disease : current knowledge and future scenarios / topic editors Antonio Cerasa, Giacomo Koch, Alfonso Fasano and Francesca Morgante. France : Frontiers Media SA, 2015 1 online resource (99 pages) : illustrations; digital file(s). text txt rdacontent computer c rdamedia online resource cr rdacarrier text file rda Frontiers Research Topics Bibliographic Level Mode of Issuance: Monograph Levodopa-induced dyskinesias (LID) are abnormal movements that occur during the period of maximal benefit of parkinsonian symptoms when levodopa concentration in the brain is highest. LID are mainly choreic in nature and represent a very common problem in up to 80% of Parkinson’s disease (PD) patients treated with levodopa. Current knowledge highlights the critical involvement of the striato-thalamo-cortical pathways, which are characterized by abnormal physiological overactivity. However, despite many recent advances in genetic and pharmacological fields, the pathophysiological mechanisms underlying LID are still a matter of debateIn the last few years, advances in the neurophysiological and neuroimaging fields have provided alternative scenarios for understanding the neurobiological mechanisms of LID. Indeed, several lines of evidence support the notion that others structures, outside traditional striato-thalamo-cortical pathways, are strongly involved in the LID. In particular, the cerebello-thalamic circuitry as well as intra-cortical connections between the premotor cortex (particularly supplementary motor area) and the inferior frontal cortex, would seem to play a key role in the dysfunctional pathophysiological model of LID.This topic aims to pool the most recent advances in the phenomenology and pathophysiology of levodopa-induced dyskinesias. We aim to compile original research papers, review articles, technical reports and commentaries that cover this topic broadly. Researchers with interest in clinical aspects (and particularly management strategies, e.g. deep-brain stimulation), neuroimaging (using either functional or structural MRI approaches), neurophysiology (transcranial magnetic stimulation (TMS)) of LID and other hyperkinetic movement disorders (i.e., dystonia, Huntington's disease, Gilles de la Tourette's syndrome), are encouraged to contribute to this topic. Again, articles concerning animal models of PD will be particularly appreciated. English Includes bibliographical references. Neurology HILCC Medicine HILCC Health & Biological Sciences HILCC Fasano, Alfonso, editor. Koch, Giacomo, editor. Cerasa, Antonio, editor. Frontiers Research Topics. |
language |
English |
format |
eBook |
author2 |
Fasano, Alfonso, Koch, Giacomo, Cerasa, Antonio, |
author_facet |
Fasano, Alfonso, Koch, Giacomo, Cerasa, Antonio, |
author2_variant |
a f af g k gk a c ac |
author2_role |
TeilnehmendeR TeilnehmendeR TeilnehmendeR |
title |
Levodopa-induced dyskinesias in Parkinson's disease : current knowledge and future scenarios / |
spellingShingle |
Levodopa-induced dyskinesias in Parkinson's disease : current knowledge and future scenarios / Frontiers Research Topics |
title_sub |
current knowledge and future scenarios / |
title_full |
Levodopa-induced dyskinesias in Parkinson's disease : current knowledge and future scenarios / topic editors Antonio Cerasa, Giacomo Koch, Alfonso Fasano and Francesca Morgante. |
title_fullStr |
Levodopa-induced dyskinesias in Parkinson's disease : current knowledge and future scenarios / topic editors Antonio Cerasa, Giacomo Koch, Alfonso Fasano and Francesca Morgante. |
title_full_unstemmed |
Levodopa-induced dyskinesias in Parkinson's disease : current knowledge and future scenarios / topic editors Antonio Cerasa, Giacomo Koch, Alfonso Fasano and Francesca Morgante. |
title_auth |
Levodopa-induced dyskinesias in Parkinson's disease : current knowledge and future scenarios / |
title_new |
Levodopa-induced dyskinesias in Parkinson's disease : |
title_sort |
levodopa-induced dyskinesias in parkinson's disease : current knowledge and future scenarios / |
series |
Frontiers Research Topics |
series2 |
Frontiers Research Topics |
publisher |
Frontiers Media SA, |
publishDate |
2015 |
physical |
1 online resource (99 pages) : illustrations; digital file(s). |
isbn |
9782889193080 |
callnumber-first |
R - Medicine |
callnumber-subject |
RC - Internal Medicine |
callnumber-label |
RC376 |
callnumber-sort |
RC 3376.5 |
illustrated |
Illustrated |
work_keys_str_mv |
AT fasanoalfonso levodopainduceddyskinesiasinparkinsonsdiseasecurrentknowledgeandfuturescenarios AT kochgiacomo levodopainduceddyskinesiasinparkinsonsdiseasecurrentknowledgeandfuturescenarios AT cerasaantonio levodopainduceddyskinesiasinparkinsonsdiseasecurrentknowledgeandfuturescenarios |
status_str |
n |
ids_txt_mv |
(CKB)3710000000569647 (SSID)ssj0001679931 (PQKBManifestationID)16490909 (PQKBTitleCode)TC0001679931 (PQKBWorkID)15023518 (PQKB)11088096 (WaSeSS)IndRDA00055886 (EXLCZ)993710000000569647 |
carrierType_str_mv |
cr |
hierarchy_parent_title |
Frontiers Research Topics |
is_hierarchy_title |
Levodopa-induced dyskinesias in Parkinson's disease : current knowledge and future scenarios / |
container_title |
Frontiers Research Topics |
author2_original_writing_str_mv |
noLinkedField noLinkedField noLinkedField |
_version_ |
1796648777910583296 |
fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>03557nam a2200445 i 4500</leader><controlfield tag="001">993547796304498</controlfield><controlfield tag="005">20230621135322.0</controlfield><controlfield tag="006">m o u </controlfield><controlfield tag="007">cr#||#||||||||</controlfield><controlfield tag="008">160829s2015 fr a ob 000 u eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9782889193080</subfield><subfield code="q">(ebook)</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(CKB)3710000000569647</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(SSID)ssj0001679931</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(PQKBManifestationID)16490909</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(PQKBTitleCode)TC0001679931</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(PQKBWorkID)15023518</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(PQKB)11088096</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(WaSeSS)IndRDA00055886</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(EXLCZ)993710000000569647</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">PQKB</subfield><subfield code="b">eng</subfield><subfield code="d">UkMaJRU</subfield><subfield code="e">rda</subfield></datafield><datafield tag="041" ind1=" " ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="4"><subfield code="a">RC376.5</subfield></datafield><datafield tag="245" ind1="0" ind2="0"><subfield code="a">Levodopa-induced dyskinesias in Parkinson's disease :</subfield><subfield code="b">current knowledge and future scenarios /</subfield><subfield code="c">topic editors Antonio Cerasa, Giacomo Koch, Alfonso Fasano and Francesca Morgante.</subfield></datafield><datafield tag="264" ind1="3" ind2="1"><subfield code="a">France :</subfield><subfield code="b">Frontiers Media SA,</subfield><subfield code="c">2015</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 online resource (99 pages) :</subfield><subfield code="b">illustrations; digital file(s).</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">computer</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">online resource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="347" ind1=" " ind2=" "><subfield code="a">text file</subfield><subfield code="2">rda</subfield></datafield><datafield tag="490" ind1="1" ind2=" "><subfield code="a">Frontiers Research Topics</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Bibliographic Level Mode of Issuance: Monograph</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Levodopa-induced dyskinesias (LID) are abnormal movements that occur during the period of maximal benefit of parkinsonian symptoms when levodopa concentration in the brain is highest. LID are mainly choreic in nature and represent a very common problem in up to 80% of Parkinson’s disease (PD) patients treated with levodopa. Current knowledge highlights the critical involvement of the striato-thalamo-cortical pathways, which are characterized by abnormal physiological overactivity. However, despite many recent advances in genetic and pharmacological fields, the pathophysiological mechanisms underlying LID are still a matter of debateIn the last few years, advances in the neurophysiological and neuroimaging fields have provided alternative scenarios for understanding the neurobiological mechanisms of LID. Indeed, several lines of evidence support the notion that others structures, outside traditional striato-thalamo-cortical pathways, are strongly involved in the LID. In particular, the cerebello-thalamic circuitry as well as intra-cortical connections between the premotor cortex (particularly supplementary motor area) and the inferior frontal cortex, would seem to play a key role in the dysfunctional pathophysiological model of LID.This topic aims to pool the most recent advances in the phenomenology and pathophysiology of levodopa-induced dyskinesias. We aim to compile original research papers, review articles, technical reports and commentaries that cover this topic broadly. Researchers with interest in clinical aspects (and particularly management strategies, e.g. deep-brain stimulation), neuroimaging (using either functional or structural MRI approaches), neurophysiology (transcranial magnetic stimulation (TMS)) of LID and other hyperkinetic movement disorders (i.e., dystonia, Huntington's disease, Gilles de la Tourette's syndrome), are encouraged to contribute to this topic. Again, articles concerning animal models of PD will be particularly appreciated.</subfield></datafield><datafield tag="546" ind1=" " ind2=" "><subfield code="a">English</subfield></datafield><datafield tag="504" ind1=" " ind2=" "><subfield code="a">Includes bibliographical references.</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Neurology</subfield><subfield code="2">HILCC</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Medicine</subfield><subfield code="2">HILCC</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Health & Biological Sciences</subfield><subfield code="2">HILCC</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Fasano, Alfonso,</subfield><subfield code="e">editor.</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Koch, Giacomo,</subfield><subfield code="e">editor.</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cerasa, Antonio,</subfield><subfield code="e">editor.</subfield></datafield><datafield tag="830" ind1=" " ind2="0"><subfield code="a">Frontiers Research Topics.</subfield></datafield><datafield tag="ADM" ind1=" " ind2=" "><subfield code="b">2023-06-25 10:02:01 Europe/Vienna</subfield><subfield code="d">00</subfield><subfield code="f">system</subfield><subfield code="c">marc21</subfield><subfield code="a">2016-01-23 20:51:17 Europe/Vienna</subfield><subfield code="g">false</subfield></datafield><datafield tag="AVE" ind1=" " ind2=" "><subfield code="i">DOAB Directory of Open Access Books</subfield><subfield code="P">DOAB Directory of Open Access Books</subfield><subfield code="x">https://eu02.alma.exlibrisgroup.com/view/uresolver/43ACC_OEAW/openurl?u.ignore_date_coverage=true&portfolio_pid=5338601440004498&Force_direct=true</subfield><subfield code="Z">5338601440004498</subfield><subfield code="b">Available</subfield><subfield code="8">5338601440004498</subfield></datafield></record></collection> |