Application of genetically encoded indicators to mammalian central nervous system / edited by Yoshiyuki Yamada and Katsuhiko Mikoshiba.
Genetically encoded indicators emerged as promising tools for cell type-specific and chronic recording of neuronal population activity. Since publication of the first prototypical genetically encoded Ca2+ indicators (Cameleons) in 1997, we have witnessed remarkable evolution of the field, with rapid...
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| Superior document: | Frontiers Research Topics, |
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| TeilnehmendeR: | |
| Place / Publishing House: | [Place of publication not identified] : : Frontiers Media SA,, 2016. |
| Year of Publication: | 2016 |
| Language: | English |
| Series: | Frontiers Research Topics,
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| Physical Description: | 1 online resource (116 pages) :; illustrations; digital file(s). |
| Notes: | "Published in: Frontiers in molecular neuroscience" --front cover. |
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Table of Contents:
- Editorial: application of genetically encoded indicators to mammalian central nervous system
- Monitoring activity in neural circuits with genetically encoded indicators
- Putting a finishing touch on GECIs
- Genetically encoded Ca²⁺ indicators; expanded affinity range, color hue and compatibility with optogenetics
- Investigating neuronal function with optically controllable proteins
- Exploration of genetically encoded voltage indicators based on a chimeric voltage sensing domain
- Engineering a genetically-encoded SHG chromophore by electrostatic targeting to the membrane
- Imaging activity in astrocytes and neurones with genetically encoded calcium indicators following in utero electroporation
- Intracellular calcium dynamics in cortical microglia responding to focal laser injury in the PC::G5-tdT reporter mouse
- Wide-field Ca²⁺ imaging reveals visually evoked activity in the retrosplenial area
- Habituation of glomerular responses in the olfactory bulb following prolonged odor stimulation reflects reduced peripheral input.