PI3K signalling / / topic editors, Klaus Okkenhaug, Martin Turner and Michael R. Gold.
The PI3Ks control many key functions in immune cells. PI3Ks phosphorylate PtdIns(4,5)P2 to yield PtdIns(3,4,5)P3. Initially, PI3K inhibitors such as Wortmannin, LY294002 and Rapamycin were used to establish a central role for Pi3K pathway in immune cells. Considerable progress in understanding the r...
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Place / Publishing House: | [Lausanne, Switzerland] : : Frontiers Media SA,, 2015. |
Year of Publication: | 2015 |
Language: | English |
Series: | Frontiers Research Topics,
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Physical Description: | 1 online resource (139 pages). |
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