Models and estimation of genetic effects / / topic editors : José M. Álvarez-Castro and Rong-Cai Yang.

• Author: Rong-Cai Yang
• TeilnehmendeR: Álvarez-Castro, José M.; Yang, Rong-Cai
• Place / Publishing House: France : : Frontiers Media SA,, 2015
• Year of Publication: 2015
• Language: English
• Series: Frontiers Research Topics
• Physical Description: 1 online resource (99 pages) :; illustrations; digital, PDF file(s).
• Notes: Bibliographic Level Mode of Issuance: Monograph

Ronald Fisher needed to develop elaborate models of genetic effects in order to set the foundations of Quantitative Genetics in his 1918 paper “The correlation between relatives on the supposition of Mendelian inheritance”. Since then, many significant implementations have been made to model genetic effects. However, at the verge of one century after Fisher’s kick-off, models of genetic effects keep on being discussed and implemented. Indeed, the relatively recent advent of QTL analyses challenged the state of the art of this field by providing researchers the opportunity to obtain and analyse estimates of genetic effects from real data. In this context, the development of this field was not exempt of some polemics, like the debate about the convenience of the functional and the statistical epistasis approaches. This research topic is meant to provide recent developments in models of genetic effects and to enrich the discussion about how and why models of genetic effects must be further developed and applied.