Amyloid-beta clearance in Alzheimer's disease / topic editors: Robert A. Marr and Eliezer Masliah.
Strong evidence continues to accumulate indicating that amyloid-beta (Aβ) is a central part of Alzheimer’s disease (AD) pathogenesis in spite of the negative evidence coming from failed clinical trials. Therefore, mechanisms of clearance of Aβ are of great interest in understanding AD pathogenesis a...
Saved in:
| Superior document: | Frontiers in aging neuroscience |
|---|---|
| : | |
| Place / Publishing House: | [Place of publication not identified] : : Frontiers Media SA,, 2015. ©2015 |
| Year of Publication: | 2015 |
| Language: | English |
| Series: | Frontiers in aging neuroscience.
|
| Physical Description: | 1 online resource (111 pages) :; illustrations; digital, PDF file(s). |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| LEADER | 02625nam a2200517 i 4500 | ||
|---|---|---|---|
| 001 | 993547173004498 | ||
| 005 | 20231130164743.0 | ||
| 006 | m fo d 000 00 | ||
| 007 | cr#c|#---||||| | ||
| 008 | 160208s2015uuuuxx ad||fob 000-0 eng|d | ||
| 035 | |a (CKB)3710000000586918 | ||
| 035 | |a (oapen)https://directory.doabooks.org/handle/20.500.12854/40785 | ||
| 035 | |a (EXLCZ)993710000000586918 | ||
| 040 | |d UkMaJRU |e rda | ||
| 041 | 0 | |a eng | |
| 082 | 0 | 0 | |a 616.831 |2 23 |
| 100 | 1 | |a Robert Marr |4 auth | |
| 245 | 0 | 0 | |a Amyloid-beta clearance in Alzheimer's disease |h [electronic resource] / |c topic editors: Robert A. Marr and Eliezer Masliah. |
| 260 | |b Frontiers Media SA |c 2015 | ||
| 264 | 1 | |a [Place of publication not identified] : |b Frontiers Media SA, |c 2015. | |
| 264 | 4 | |c ©2015 | |
| 300 | |a 1 online resource (111 pages) : |b illustrations; digital, PDF file(s). | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 347 | |a text file |b PDF |2 rda | ||
| 490 | 0 | |a Frontiers research topics | |
| 490 | 1 | |a Frontiers in aging neuroscience | |
| 504 | |a Includes bibliographical references. | ||
| 506 | |a Open access |f Unrestricted online access |2 star | ||
| 520 | 3 | |a Strong evidence continues to accumulate indicating that amyloid-beta (Aβ) is a central part of Alzheimer’s disease (AD) pathogenesis in spite of the negative evidence coming from failed clinical trials. Therefore, mechanisms of clearance of Aβ are of great interest in understanding AD pathogenesis and the development of effective treatments. This topic focuses on the issues related to Aβ clearance in AD. The topics covered include proteases that degrade Aβ and their localization, regulation, and functions. This topic also covers issues related to clearance through uptake by glia and through low-density lipoprotein (LDL) receptor mediated mechanisms. Signal transduction related to AD pathology and clearance is also addressed. Finally, immunotherapy and other novel therapeutic approaches are discussed. | |
| 588 | |a Description based on e-publication, viewed on July 24, 2018. | ||
| 546 | |a English | ||
| 650 | 0 | |a Alzheimer's disease. | |
| 650 | 0 | |a Alzheimer's disease |x Pathogenesis. | |
| 650 | 0 | |a Alzheimer's disease |x Molecular aspects. | |
| 650 | 0 | |a Neurosciences. | |
| 653 | |a amyloid-beta | ||
| 653 | |a Signal Transduction | ||
| 653 | |a Proteases | ||
| 653 | |a LDL receptors | ||
| 653 | |a Clearance | ||
| 653 | |a Alzheimer's disease | ||
| 776 | |z 2-88919-443-4 | ||
| 700 | 1 | |a Eliezer Masliah |4 auth | |
| 830 | 0 | |a Frontiers in aging neuroscience. | |
| 906 | |a BOOK | ||
| ADM | |b 2023-12-01 00:39:20 Europe/Vienna |d 00 |f system |c marc21 |a 2016-02-13 18:39:49 Europe/Vienna |g false | ||
| AVE | |i DOAB Directory of Open Access Books |P DOAB Directory of Open Access Books |x https://eu02.alma.exlibrisgroup.com/view/uresolver/43ACC_OEAW/openurl?u.ignore_date_coverage=true&portfolio_pid=5338434460004498&Force_direct=true |Z 5338434460004498 |b Available |8 5338434460004498 | ||