Programming the HPA-axis by early life experience : : mechanisms of stress susceptibility and adaptation / / topic editors, Nikolaos P. Daskalakis and Rachel Yehuda.
Experiences during early life program the central nervous- and endocrine-systems with consequences for susceptibility to physical and mental disorders. These programming effects depend on genetic and epigenetic factors, and their outcome leads to an adaptive or maladaptive phenotype to a given later...
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| Place / Publishing House: | [Lausanne, Switzerland] : : Frontiers Media SA,, 2015. |
| Year of Publication: | 2015 |
| Language: | English |
| Series: | Frontiers Research Topics,
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| Physical Description: | 1 online resource (140 pages). |
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| Summary: | Experiences during early life program the central nervous- and endocrine-systems with consequences for susceptibility to physical and mental disorders. These programming effects depend on genetic and epigenetic factors, and their outcome leads to an adaptive or maladaptive phenotype to a given later environmental context. This Research Topic focused on the hypothalamus-pituitary-adrenal (HPA)-axis and stress-related phenotypes, and on how HPA-axis programming by the environment precisely occurs. We included original research, mini-review and review papers on a broad range of topics related to HPA-axis programming. |
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| Bibliography: | Includes bibliographical references. |
| ISSN: | 1664-8714 |
| Hierarchical level: | Monograph |
| Statement of Responsibility: | topic editors, Nikolaos P. Daskalakis and Rachel Yehuda. |