Antibody engineering / / edited by Thomas Böldicke.
Antibody Engineering comprises in vitro selection and modification of human antibodies including humanization of mouse antibodies for therapy, diagnosis, and research. This book comprises an overview about the generation of antibody diversity and essential techniques in antibody engineering: constru...
Saved in:
| : | |
|---|---|
| TeilnehmendeR: | |
| Place / Publishing House: | Rijeka, Croatia : : IntechOpen,, [2018] ©2018 |
| Year of Publication: | 2018 |
| Language: | English |
| Physical Description: | 1 online resource (312 pages) |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| LEADER | 02435nam a2200457 i 4500 | ||
|---|---|---|---|
| 001 | 993546928904498 | ||
| 005 | 20240124160313.0 | ||
| 006 | m o d | ||
| 007 | cr#||||||||||| | ||
| 008 | 221012s2018 ci o 000 0 eng d | ||
| 020 | |a 953-51-3975-4 | ||
| 020 | |a 953-51-3826-X | ||
| 035 | |a (CKB)4100000002890934 | ||
| 035 | |a (NjHacI)994100000002890934 | ||
| 035 | |a (oapen)https://directory.doabooks.org/handle/20.500.12854/40952 | ||
| 035 | |a (EXLCZ)994100000002890934 | ||
| 040 | |a NjHacI |b eng |e rda |c NjHacl | ||
| 041 | 0 | |a eng | |
| 050 | 4 | |a QR186.7 |b .A585 2018 | |
| 082 | 0 | 4 | |a 616.0798 |2 23 |
| 100 | 1 | |a Thomas Böldicke |4 auth | |
| 245 | 0 | 0 | |a Antibody engineering / |c edited by Thomas Böldicke. |
| 260 | |b IntechOpen |c 2018 | ||
| 264 | 1 | |a Rijeka, Croatia : |b IntechOpen, |c [2018] | |
| 264 | 4 | |c ©2018 | |
| 300 | |a 1 online resource (312 pages) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 506 | |a Open access |f Unrestricted online access |2 star | ||
| 588 | |a Description based on: online resource; title from PDF information screen (Intech, viewed October 12, 2022). | ||
| 520 | |a Antibody Engineering comprises in vitro selection and modification of human antibodies including humanization of mouse antibodies for therapy, diagnosis, and research. This book comprises an overview about the generation of antibody diversity and essential techniques in antibody engineering: construction of immune, naive and synthetic libraries, all available in vitro display methods, humanization by chain shuffling, affinity maturation techniques, de novo synthesis of antibody genes, colony assays for library screening, construction of scFvs from hybridomas, and purification of monoclonal antibodies by exclusion chromatography. In addition, other topics that are discussed in this book are application and mechanism of single domain antibodies, structural diversity of antibodies, immune-mediated skin reactions induced by TNF-alpha recombinant antibodies, and bioinformatic approaches to select pathogen-derived peptide sequences for antibody targets. | ||
| 546 | |a English | ||
| 650 | 0 | |a Immunoglobulins. | |
| 653 | |a Life Sciences | ||
| 653 | |a Human Genetics | ||
| 653 | |a Molecular Genetics | ||
| 653 | |a Genetics and Molecular Biology | ||
| 653 | |a Biochemistry | ||
| 776 | |z 953-51-3825-1 | ||
| 700 | 1 | |a Böldicke, Thomas, |e editor. | |
| 906 | |a BOOK | ||
| ADM | |b 2024-01-25 02:20:44 Europe/Vienna |f system |c marc21 |a 2018-04-07 19:23:49 Europe/Vienna |g false | ||
| AVE | |i DOAB Directory of Open Access Books |P DOAB Directory of Open Access Books |x https://eu02.alma.exlibrisgroup.com/view/uresolver/43ACC_OEAW/openurl?u.ignore_date_coverage=true&portfolio_pid=5351671450004498&Force_direct=true |Z 5351671450004498 |b Available |8 5351671450004498 | ||