New Insights into Microbial Ecology through Subtle Nucleotide Variation
The 16S ribosomal RNA gene commonly serves as a molecular marker for investigating microbial community composition and structure. Vast amounts of 16S rRNA amplicon data generated from environmental samples thanks to the recent advances in sequencing technologies allowed microbial ecologists to explo...
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Superior document: | Frontiers Research Topics |
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Year of Publication: | 2016 |
Language: | English |
Series: | Frontiers Research Topics
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Physical Description: | 1 electronic resource (133 p.) |
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A. Murat Eren auth New Insights into Microbial Ecology through Subtle Nucleotide Variation Frontiers Media SA 2016 1 electronic resource (133 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier Frontiers Research Topics The 16S ribosomal RNA gene commonly serves as a molecular marker for investigating microbial community composition and structure. Vast amounts of 16S rRNA amplicon data generated from environmental samples thanks to the recent advances in sequencing technologies allowed microbial ecologists to explore microbial community dynamics over temporal and spatial scales deeper than ever before. However, widely used methods for the analysis of bacterial communities generally ignore subtle nucleotide variations among high-throughput sequencing reads and often fail to resolve ecologically meaningful differences between closely related organisms in complex microbial datasets. Lack of proper partitioning of the sequencing data into relevant units often masks important ecological patterns. Our research topic contains articles that use oligotyping to demonstrate the importantance of high-resolution analyses of marker gene data, and providides further evidence why microbial ecologists should open the "black box" of OTUs identified through arbitrary sequence similarity thresholds. English high-resolution oligotyping Minimum Entropy Decomposition microbiome 16S rRNA gene 2-88919-988-6 Mitchell Sogin auth Lois Maignien auth |
language |
English |
format |
eBook |
author |
A. Murat Eren |
spellingShingle |
A. Murat Eren New Insights into Microbial Ecology through Subtle Nucleotide Variation Frontiers Research Topics |
author_facet |
A. Murat Eren Mitchell Sogin Lois Maignien |
author_variant |
a m e ame |
author2 |
Mitchell Sogin Lois Maignien |
author2_variant |
m s ms l m lm |
author_sort |
A. Murat Eren |
title |
New Insights into Microbial Ecology through Subtle Nucleotide Variation |
title_full |
New Insights into Microbial Ecology through Subtle Nucleotide Variation |
title_fullStr |
New Insights into Microbial Ecology through Subtle Nucleotide Variation |
title_full_unstemmed |
New Insights into Microbial Ecology through Subtle Nucleotide Variation |
title_auth |
New Insights into Microbial Ecology through Subtle Nucleotide Variation |
title_new |
New Insights into Microbial Ecology through Subtle Nucleotide Variation |
title_sort |
new insights into microbial ecology through subtle nucleotide variation |
series |
Frontiers Research Topics |
series2 |
Frontiers Research Topics |
publisher |
Frontiers Media SA |
publishDate |
2016 |
physical |
1 electronic resource (133 p.) |
isbn |
2-88919-988-6 |
illustrated |
Not Illustrated |
work_keys_str_mv |
AT amurateren newinsightsintomicrobialecologythroughsubtlenucleotidevariation AT mitchellsogin newinsightsintomicrobialecologythroughsubtlenucleotidevariation AT loismaignien newinsightsintomicrobialecologythroughsubtlenucleotidevariation |
status_str |
n |
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(CKB)3800000000216243 (oapen)https://directory.doabooks.org/handle/20.500.12854/54590 (EXLCZ)993800000000216243 |
carrierType_str_mv |
cr |
hierarchy_parent_title |
Frontiers Research Topics |
is_hierarchy_title |
New Insights into Microbial Ecology through Subtle Nucleotide Variation |
container_title |
Frontiers Research Topics |
author2_original_writing_str_mv |
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1787548858762395649 |
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