Inhibiting PARP as a Strategic Target in Cancer
Poly-ADP ribose polymerase (PARP) proteins are critical mediators of DNA repair. Many traditional anti-cancer chemotherapy agents overwhelm a cell’s ability to repair DNA damage in order to kill proliferating malignant cells. Recent evidence suggests that cancers within and across tissue types have...
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| Superior document: | Frontiers Research Topics |
|---|---|
| : | |
| Year of Publication: | 2016 |
| Language: | English |
| Series: | Frontiers Research Topics
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| Physical Description: | 1 electronic resource (97 p.) |
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