Emerging Role of Lipids in Metabolism and Disease
Even though initially considered as a passive means for storing energy, lipids are now regarded as multifaceted molecules with crucial structural and functional activities. For instance, some of them play essential roles as key components of cell membranes whereas others act as signaling molecules i...
Saved in:
| HerausgeberIn: | |
|---|---|
| Sonstige: | |
| Year of Publication: | 2021 |
| Language: | English |
| Physical Description: | 1 electronic resource (308 p.) |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| id |
993546346704498 |
|---|---|
| ctrlnum |
(CKB)5400000000045400 (oapen)https://directory.doabooks.org/handle/20.500.12854/68544 (EXLCZ)995400000000045400 |
| collection |
bib_alma |
| record_format |
marc |
| spelling |
Pallottini, Valentina edt Emerging Role of Lipids in Metabolism and Disease Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021 1 electronic resource (308 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier Even though initially considered as a passive means for storing energy, lipids are now regarded as multifaceted molecules with crucial structural and functional activities. For instance, some of them play essential roles as key components of cell membranes whereas others act as signaling molecules in the regulation of cell homeostasis. In recent years, lipid research has attracted increasing interest because of the involvement of this class of compounds in human health. Indeed, a plethora of pathological conditions are characterized by alterations in lipid metabolism, such as cardiovascular diseases and brain disorders. This Special Issue is a collection of papers from different experts in lipid research, with the aim of providing new insights into the physiopathological involvement of lipids and their impact on human health. This collection also demonstrates the usefulness of interdisciplinary approaches in the development of novel methods to study and manipulate lipid metabolism, which may represent an attractive target for designing effective therapeutic strategies to counteract numerous pathologies. English Medicine bicssc neutral sphingomyelinase radiation sphingomyelin metabolism pathology cell signaling brain adipose tissue breast cancer epinephrine breast reconstruction epicardial fat thickness visceral fat thickness high-sensitivity c-reactive protein leptin gender female hippocampus frontal cortex adiponectin haptoglobin lipocalin BDNF synaptic proteins phosphatidylinositol 4,5-bisphosphate phospholipase C cholesterol high-cholesterol diet BET proteins cell proliferation epigenetics HMGCR JQ1 LDLr lipid metabolism SREBP TMEM97 atherosclerosis diabetes mellitus cardiovascular disease chronic inflammation hyperglycemia mutations lipid fatty acid glyceride steroid phospholipid oral drug absorption prodrug phospholipase A2 (PLA2) acid sphingomyelinase SOD liver eicosanoids ischemic stroke ischemia lipoproteins polyunsaturated fatty acids angiogenesis high-density lipoprotein endothelial cell metabolism metabolic reprogramming pulmonary fibrosis lipid mediators sphingolipids sphingosine-1-phosphate sphingosine kinase 1 prostaglandins lysophosphatidic acid autotaxin G-protein coupled receptors lysocardiolipin acyltransferase phospholipase D oxidized phospholipids DNA damage response double strand breaks ATM ionizing radiation metabolic stress oxidative stress p53 nuclear sphingolipids lipophagy lipolysis lipid droplets lipid storage diseases lipid metabolism diseases mTORC1 TFEB Cholesterol Fatty acids Lipid mediators Lipids Lipophagy Sphingolipids 3-03943-701-1 3-03943-702-X Segatto, Marco edt Pallottini, Valentina oth Segatto, Marco oth |
| language |
English |
| format |
eBook |
| author2 |
Segatto, Marco Pallottini, Valentina Segatto, Marco |
| author_facet |
Segatto, Marco Pallottini, Valentina Segatto, Marco |
| author2_variant |
v p vp m s ms |
| author2_role |
HerausgeberIn Sonstige Sonstige |
| title |
Emerging Role of Lipids in Metabolism and Disease |
| spellingShingle |
Emerging Role of Lipids in Metabolism and Disease |
| title_full |
Emerging Role of Lipids in Metabolism and Disease |
| title_fullStr |
Emerging Role of Lipids in Metabolism and Disease |
| title_full_unstemmed |
Emerging Role of Lipids in Metabolism and Disease |
| title_auth |
Emerging Role of Lipids in Metabolism and Disease |
| title_new |
Emerging Role of Lipids in Metabolism and Disease |
| title_sort |
emerging role of lipids in metabolism and disease |
| publisher |
MDPI - Multidisciplinary Digital Publishing Institute |
| publishDate |
2021 |
| physical |
1 electronic resource (308 p.) |
| isbn |
3-03943-701-1 3-03943-702-X |
| illustrated |
Not Illustrated |
| work_keys_str_mv |
AT pallottinivalentina emergingroleoflipidsinmetabolismanddisease AT segattomarco emergingroleoflipidsinmetabolismanddisease |
| status_str |
n |
| ids_txt_mv |
(CKB)5400000000045400 (oapen)https://directory.doabooks.org/handle/20.500.12854/68544 (EXLCZ)995400000000045400 |
| carrierType_str_mv |
cr |
| is_hierarchy_title |
Emerging Role of Lipids in Metabolism and Disease |
| author2_original_writing_str_mv |
noLinkedField noLinkedField noLinkedField |
| _version_ |
1787548717627211776 |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>05091nam-a2201465z--4500</leader><controlfield tag="001">993546346704498</controlfield><controlfield tag="005">20231214133053.0</controlfield><controlfield tag="006">m o d </controlfield><controlfield tag="007">cr|mn|---annan</controlfield><controlfield tag="008">202105s2021 xx |||||o ||| 0|eng d</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(CKB)5400000000045400</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(oapen)https://directory.doabooks.org/handle/20.500.12854/68544</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(EXLCZ)995400000000045400</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Pallottini, Valentina</subfield><subfield code="4">edt</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Emerging Role of Lipids in Metabolism and Disease</subfield></datafield><datafield tag="260" ind1=" " ind2=" "><subfield code="a">Basel, Switzerland</subfield><subfield code="b">MDPI - Multidisciplinary Digital Publishing Institute</subfield><subfield code="c">2021</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 electronic resource (308 p.)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">computer</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">online resource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Even though initially considered as a passive means for storing energy, lipids are now regarded as multifaceted molecules with crucial structural and functional activities. For instance, some of them play essential roles as key components of cell membranes whereas others act as signaling molecules in the regulation of cell homeostasis. In recent years, lipid research has attracted increasing interest because of the involvement of this class of compounds in human health. Indeed, a plethora of pathological conditions are characterized by alterations in lipid metabolism, such as cardiovascular diseases and brain disorders. This Special Issue is a collection of papers from different experts in lipid research, with the aim of providing new insights into the physiopathological involvement of lipids and their impact on human health. This collection also demonstrates the usefulness of interdisciplinary approaches in the development of novel methods to study and manipulate lipid metabolism, which may represent an attractive target for designing effective therapeutic strategies to counteract numerous pathologies.</subfield></datafield><datafield tag="546" ind1=" " ind2=" "><subfield code="a">English</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Medicine</subfield><subfield code="2">bicssc</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">neutral sphingomyelinase</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">radiation</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">sphingomyelin metabolism</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">pathology</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cell signaling</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">brain</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">adipose tissue</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">breast cancer</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">epinephrine</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">breast reconstruction</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">epicardial fat thickness</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">visceral fat thickness</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">high-sensitivity c-reactive protein</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">leptin</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">gender</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">female</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">hippocampus</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">frontal cortex</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">adiponectin</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">haptoglobin</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">lipocalin</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">BDNF</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">synaptic proteins</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">phosphatidylinositol 4,5-bisphosphate</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">phospholipase C</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cholesterol</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">high-cholesterol diet</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">BET proteins</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cell proliferation</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">epigenetics</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">HMGCR</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">JQ1</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">LDLr</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">lipid metabolism</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">SREBP</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">TMEM97</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">atherosclerosis</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">diabetes mellitus</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cardiovascular disease</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">chronic inflammation</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">hyperglycemia</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mutations</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">lipid</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">fatty acid</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">glyceride</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">steroid</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">phospholipid</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">oral drug absorption</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">prodrug</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">phospholipase A2 (PLA2)</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">acid sphingomyelinase</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">SOD</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">liver</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">eicosanoids</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ischemic stroke</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ischemia</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">lipoproteins</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">polyunsaturated fatty acids</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">angiogenesis</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">high-density lipoprotein</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">endothelial cell</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">metabolism</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">metabolic reprogramming</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">pulmonary fibrosis</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">lipid mediators</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">sphingolipids</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">sphingosine-1-phosphate</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">sphingosine kinase 1</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">prostaglandins</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">lysophosphatidic acid</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">autotaxin</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">G-protein coupled receptors</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">lysocardiolipin acyltransferase</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">phospholipase D</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">oxidized phospholipids</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">DNA damage response</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">double strand breaks</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ATM</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ionizing radiation</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">metabolic stress</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">oxidative stress</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">p53</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">nuclear sphingolipids</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">lipophagy</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">lipolysis</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">lipid droplets</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">lipid storage diseases</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">lipid metabolism diseases</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mTORC1</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">TFEB</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Cholesterol</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Fatty acids</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Lipid mediators</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Lipids</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Lipophagy</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Sphingolipids</subfield></datafield><datafield tag="776" ind1=" " ind2=" "><subfield code="z">3-03943-701-1</subfield></datafield><datafield tag="776" ind1=" " ind2=" "><subfield code="z">3-03943-702-X</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Segatto, Marco</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Pallottini, Valentina</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Segatto, Marco</subfield><subfield code="4">oth</subfield></datafield><datafield tag="906" ind1=" " ind2=" "><subfield code="a">BOOK</subfield></datafield><datafield tag="ADM" ind1=" " ind2=" "><subfield code="b">2023-12-15 05:41:49 Europe/Vienna</subfield><subfield code="f">system</subfield><subfield code="c">marc21</subfield><subfield code="a">2022-04-04 09:22:53 Europe/Vienna</subfield><subfield code="g">false</subfield></datafield><datafield tag="AVE" ind1=" " ind2=" "><subfield code="i">DOAB Directory of Open Access Books</subfield><subfield code="P">DOAB Directory of Open Access Books</subfield><subfield code="x">https://eu02.alma.exlibrisgroup.com/view/uresolver/43ACC_OEAW/openurl?u.ignore_date_coverage=true&portfolio_pid=5338236570004498&Force_direct=true</subfield><subfield code="Z">5338236570004498</subfield><subfield code="b">Available</subfield><subfield code="8">5338236570004498</subfield></datafield></record></collection> |