Emerging Role of Lipids in Metabolism and Disease
Even though initially considered as a passive means for storing energy, lipids are now regarded as multifaceted molecules with crucial structural and functional activities. For instance, some of them play essential roles as key components of cell membranes whereas others act as signaling molecules i...
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Pallottini, Valentina edt Emerging Role of Lipids in Metabolism and Disease Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021 1 electronic resource (308 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier Even though initially considered as a passive means for storing energy, lipids are now regarded as multifaceted molecules with crucial structural and functional activities. For instance, some of them play essential roles as key components of cell membranes whereas others act as signaling molecules in the regulation of cell homeostasis. In recent years, lipid research has attracted increasing interest because of the involvement of this class of compounds in human health. Indeed, a plethora of pathological conditions are characterized by alterations in lipid metabolism, such as cardiovascular diseases and brain disorders. This Special Issue is a collection of papers from different experts in lipid research, with the aim of providing new insights into the physiopathological involvement of lipids and their impact on human health. This collection also demonstrates the usefulness of interdisciplinary approaches in the development of novel methods to study and manipulate lipid metabolism, which may represent an attractive target for designing effective therapeutic strategies to counteract numerous pathologies. English Medicine bicssc neutral sphingomyelinase radiation sphingomyelin metabolism pathology cell signaling brain adipose tissue breast cancer epinephrine breast reconstruction epicardial fat thickness visceral fat thickness high-sensitivity c-reactive protein leptin gender female hippocampus frontal cortex adiponectin haptoglobin lipocalin BDNF synaptic proteins phosphatidylinositol 4,5-bisphosphate phospholipase C cholesterol high-cholesterol diet BET proteins cell proliferation epigenetics HMGCR JQ1 LDLr lipid metabolism SREBP TMEM97 atherosclerosis diabetes mellitus cardiovascular disease chronic inflammation hyperglycemia mutations lipid fatty acid glyceride steroid phospholipid oral drug absorption prodrug phospholipase A2 (PLA2) acid sphingomyelinase SOD liver eicosanoids ischemic stroke ischemia lipoproteins polyunsaturated fatty acids angiogenesis high-density lipoprotein endothelial cell metabolism metabolic reprogramming pulmonary fibrosis lipid mediators sphingolipids sphingosine-1-phosphate sphingosine kinase 1 prostaglandins lysophosphatidic acid autotaxin G-protein coupled receptors lysocardiolipin acyltransferase phospholipase D oxidized phospholipids DNA damage response double strand breaks ATM ionizing radiation metabolic stress oxidative stress p53 nuclear sphingolipids lipophagy lipolysis lipid droplets lipid storage diseases lipid metabolism diseases mTORC1 TFEB Cholesterol Fatty acids Lipid mediators Lipids Lipophagy Sphingolipids 3-03943-701-1 3-03943-702-X Segatto, Marco edt Pallottini, Valentina oth Segatto, Marco oth |
language |
English |
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eBook |
author2 |
Segatto, Marco Pallottini, Valentina Segatto, Marco |
author_facet |
Segatto, Marco Pallottini, Valentina Segatto, Marco |
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v p vp m s ms |
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HerausgeberIn Sonstige Sonstige |
title |
Emerging Role of Lipids in Metabolism and Disease |
spellingShingle |
Emerging Role of Lipids in Metabolism and Disease |
title_full |
Emerging Role of Lipids in Metabolism and Disease |
title_fullStr |
Emerging Role of Lipids in Metabolism and Disease |
title_full_unstemmed |
Emerging Role of Lipids in Metabolism and Disease |
title_auth |
Emerging Role of Lipids in Metabolism and Disease |
title_new |
Emerging Role of Lipids in Metabolism and Disease |
title_sort |
emerging role of lipids in metabolism and disease |
publisher |
MDPI - Multidisciplinary Digital Publishing Institute |
publishDate |
2021 |
physical |
1 electronic resource (308 p.) |
isbn |
3-03943-701-1 3-03943-702-X |
illustrated |
Not Illustrated |
work_keys_str_mv |
AT pallottinivalentina emergingroleoflipidsinmetabolismanddisease AT segattomarco emergingroleoflipidsinmetabolismanddisease |
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Emerging Role of Lipids in Metabolism and Disease |
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