Radioimmunotherapy – Translational Opportunities and Challenges
Surgery, chemotherapy and radiotherapy remain the three primary approaches for treating the majority of cancers. Although the primary aim of radiotherapy is to inhibit tumor cell proliferation and induce tumor cell death by inducing DNA double-strand breaks, it is also known to have a number of immu...
Saved in:
HerausgeberIn: | |
---|---|
Sonstige: | |
Year of Publication: | 2020 |
Language: | English |
Physical Description: | 1 electronic resource (144 p.) |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
993546346304498 |
---|---|
ctrlnum |
(CKB)5400000000046037 (oapen)https://directory.doabooks.org/handle/20.500.12854/73757 (EXLCZ)995400000000046037 |
collection |
bib_alma |
record_format |
marc |
spelling |
Gaipl, Udo S. edt Radioimmunotherapy – Translational Opportunities and Challenges Frontiers Media SA 2020 1 electronic resource (144 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier Surgery, chemotherapy and radiotherapy remain the three primary approaches for treating the majority of cancers. Although the primary aim of radiotherapy is to inhibit tumor cell proliferation and induce tumor cell death by inducing DNA double-strand breaks, it is also known to have a number of immunological effects, the manipulation of which could enhance clinical efficacy. Recent insights into the immunomodulatory capacity of tumours, and the development of approaches to therapeutically exploit these have prompted the emergence of a range of immunotherapeutic approaches for inducing and enhancing robust, protective anti-tumor immunity. Combining radiotherapy with immunotherapy (radioimmunotherapy) therefore has significant clinical potential. The aim of this Research Topic is to collate primary articles, reviews and opinion pieces on the complex reciprocal relationships between the immune system, tumors and the tumour microenvironment, and the stimulatory and suppressive effects of radiotherapy on innate and adaptive immunity in the pre-clinical and clinical settings. English Medicine Oncology 2-88963-615-1 Multhoff, Gabriele edt Graham Pockley, Alan edt Rödel, Franz edt Gaipl, Udo S. oth Multhoff, Gabriele oth Graham Pockley, Alan oth Rödel, Franz oth |
language |
English |
format |
eBook |
author2 |
Multhoff, Gabriele Graham Pockley, Alan Rödel, Franz Gaipl, Udo S. Multhoff, Gabriele Graham Pockley, Alan Rödel, Franz |
author_facet |
Multhoff, Gabriele Graham Pockley, Alan Rödel, Franz Gaipl, Udo S. Multhoff, Gabriele Graham Pockley, Alan Rödel, Franz |
author2_variant |
u s g us usg g m gm p a g pa pag f r fr |
author2_role |
HerausgeberIn HerausgeberIn HerausgeberIn Sonstige Sonstige Sonstige Sonstige |
title |
Radioimmunotherapy – Translational Opportunities and Challenges |
spellingShingle |
Radioimmunotherapy – Translational Opportunities and Challenges |
title_full |
Radioimmunotherapy – Translational Opportunities and Challenges |
title_fullStr |
Radioimmunotherapy – Translational Opportunities and Challenges |
title_full_unstemmed |
Radioimmunotherapy – Translational Opportunities and Challenges |
title_auth |
Radioimmunotherapy – Translational Opportunities and Challenges |
title_new |
Radioimmunotherapy – Translational Opportunities and Challenges |
title_sort |
radioimmunotherapy – translational opportunities and challenges |
publisher |
Frontiers Media SA |
publishDate |
2020 |
physical |
1 electronic resource (144 p.) |
isbn |
2-88963-615-1 |
illustrated |
Not Illustrated |
work_keys_str_mv |
AT gaipludos radioimmunotherapytranslationalopportunitiesandchallenges AT multhoffgabriele radioimmunotherapytranslationalopportunitiesandchallenges AT grahampockleyalan radioimmunotherapytranslationalopportunitiesandchallenges AT rodelfranz radioimmunotherapytranslationalopportunitiesandchallenges |
status_str |
n |
ids_txt_mv |
(CKB)5400000000046037 (oapen)https://directory.doabooks.org/handle/20.500.12854/73757 (EXLCZ)995400000000046037 |
carrierType_str_mv |
cr |
is_hierarchy_title |
Radioimmunotherapy – Translational Opportunities and Challenges |
author2_original_writing_str_mv |
noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField noLinkedField |
_version_ |
1792213105911005184 |
fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>02166nam-a2200361z--4500</leader><controlfield tag="001">993546346304498</controlfield><controlfield tag="005">20240228021911.0</controlfield><controlfield tag="006">m o d </controlfield><controlfield tag="007">cr|mn|---annan</controlfield><controlfield tag="008">202111s2020 xx |||||o ||| 0|eng d</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(CKB)5400000000046037</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(oapen)https://directory.doabooks.org/handle/20.500.12854/73757</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(EXLCZ)995400000000046037</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Gaipl, Udo S.</subfield><subfield code="4">edt</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Radioimmunotherapy – Translational Opportunities and Challenges</subfield></datafield><datafield tag="260" ind1=" " ind2=" "><subfield code="b">Frontiers Media SA</subfield><subfield code="c">2020</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 electronic resource (144 p.)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">computer</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">online resource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Surgery, chemotherapy and radiotherapy remain the three primary approaches for treating the majority of cancers. Although the primary aim of radiotherapy is to inhibit tumor cell proliferation and induce tumor cell death by inducing DNA double-strand breaks, it is also known to have a number of immunological effects, the manipulation of which could enhance clinical efficacy. Recent insights into the immunomodulatory capacity of tumours, and the development of approaches to therapeutically exploit these have prompted the emergence of a range of immunotherapeutic approaches for inducing and enhancing robust, protective anti-tumor immunity. Combining radiotherapy with immunotherapy (radioimmunotherapy) therefore has significant clinical potential. The aim of this Research Topic is to collate primary articles, reviews and opinion pieces on the complex reciprocal relationships between the immune system, tumors and the tumour microenvironment, and the stimulatory and suppressive effects of radiotherapy on innate and adaptive immunity in the pre-clinical and clinical settings.</subfield></datafield><datafield tag="546" ind1=" " ind2=" "><subfield code="a">English</subfield></datafield><datafield tag="650" ind1=" " ind2="0"><subfield code="a">Medicine</subfield></datafield><datafield tag="650" ind1=" " ind2="0"><subfield code="a">Oncology</subfield></datafield><datafield tag="776" ind1=" " ind2=" "><subfield code="z">2-88963-615-1</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Multhoff, Gabriele</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Graham Pockley, Alan</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Rödel, Franz</subfield><subfield code="4">edt</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Gaipl, Udo S.</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Multhoff, Gabriele</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Graham Pockley, Alan</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Rödel, Franz</subfield><subfield code="4">oth</subfield></datafield><datafield tag="906" ind1=" " ind2=" "><subfield code="a">BOOK</subfield></datafield><datafield tag="ADM" ind1=" " ind2=" "><subfield code="b">2024-02-29 04:48:53 Europe/Vienna</subfield><subfield code="f">system</subfield><subfield code="c">marc21</subfield><subfield code="a">2022-04-04 09:22:53 Europe/Vienna</subfield><subfield code="g">false</subfield></datafield><datafield tag="AVE" ind1=" " ind2=" "><subfield code="i">DOAB Directory of Open Access Books</subfield><subfield code="P">DOAB Directory of Open Access Books</subfield><subfield code="x">https://eu02.alma.exlibrisgroup.com/view/uresolver/43ACC_OEAW/openurl?u.ignore_date_coverage=true&portfolio_pid=5338236450004498&Force_direct=true</subfield><subfield code="Z">5338236450004498</subfield><subfield code="b">Available</subfield><subfield code="8">5338236450004498</subfield></datafield></record></collection> |