In Vivo Imaging in Pharmacological Research
The discovery and development of a biological active molecule with therapeutic properties is an ever increasing complex task, highly unpredictable at the early stages and marked, in the end, by high rates of failure. As a consequence, the overall process leading to the production of a successful dru...
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Superior document: | Frontiers Research Topics |
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Year of Publication: | 2017 |
Language: | English |
Series: | Frontiers Research Topics
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Physical Description: | 1 electronic resource (222 p.) |
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Nicolau Beckmann auth In Vivo Imaging in Pharmacological Research Frontiers Media SA 2017 1 electronic resource (222 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier Frontiers Research Topics The discovery and development of a biological active molecule with therapeutic properties is an ever increasing complex task, highly unpredictable at the early stages and marked, in the end, by high rates of failure. As a consequence, the overall process leading to the production of a successful drug is very costly. The improvement of the net outcome in drug discovery and development would require, amongst other important factors, a good understanding of the molecular events that characterize the disease or pathology in order to better identify likely targets of interest, to optimize the interaction of an active agent (small molecule or macromolecule of natural or synthetic origin) with those targets, and to facilitate the study of the pharmacokinetics, pharmacodynamics and toxicity of an active agent in suitable models and in human subjects. The objective of this Research Topic is to highlight new developments and applications of imaging techniques with the objective of performing pharmacological studies in vivo, in animal models and in humans. In the domain of drug discovery, the pharmacological and biomedical questions constitute the center of attention. In this sense, it is fundamental to keep in mind the strengths and limitations of each analytical or imaging technique. At the end, the judicious application of the technique with the aim of supporting the search for answers to manifold questions arising during a long and painstaking path provides a continuous role for imaging within the complex area of drug discovery and development. English magnetic resonance imaging (MRI) computerized tomography(CT) positron emission tomography (PET) pharmacology single photon emission computed tomography (SPECT) imaging medical imaging ultrasound 2-88945-237-9 Albert D. Windhorst auth Igor A. Kaltashov auth |
language |
English |
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eBook |
author |
Nicolau Beckmann |
spellingShingle |
Nicolau Beckmann In Vivo Imaging in Pharmacological Research Frontiers Research Topics |
author_facet |
Nicolau Beckmann Albert D. Windhorst Igor A. Kaltashov |
author_variant |
n b nb |
author2 |
Albert D. Windhorst Igor A. Kaltashov |
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a d w adw i a k iak |
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Nicolau Beckmann |
title |
In Vivo Imaging in Pharmacological Research |
title_full |
In Vivo Imaging in Pharmacological Research |
title_fullStr |
In Vivo Imaging in Pharmacological Research |
title_full_unstemmed |
In Vivo Imaging in Pharmacological Research |
title_auth |
In Vivo Imaging in Pharmacological Research |
title_new |
In Vivo Imaging in Pharmacological Research |
title_sort |
in vivo imaging in pharmacological research |
series |
Frontiers Research Topics |
series2 |
Frontiers Research Topics |
publisher |
Frontiers Media SA |
publishDate |
2017 |
physical |
1 electronic resource (222 p.) |
isbn |
2-88945-237-9 |
illustrated |
Not Illustrated |
work_keys_str_mv |
AT nicolaubeckmann invivoimaginginpharmacologicalresearch AT albertdwindhorst invivoimaginginpharmacologicalresearch AT igorakaltashov invivoimaginginpharmacologicalresearch |
status_str |
n |
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(CKB)4100000000883851 (oapen)https://directory.doabooks.org/handle/20.500.12854/50092 (EXLCZ)994100000000883851 |
carrierType_str_mv |
cr |
hierarchy_parent_title |
Frontiers Research Topics |
is_hierarchy_title |
In Vivo Imaging in Pharmacological Research |
container_title |
Frontiers Research Topics |
author2_original_writing_str_mv |
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1796649072013082624 |
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