3D Stem Cell Culture

Recently, stem cells have been drawing increasing interest in basic and translational research that aims to understand stem cell biology and generate new therapies for various disorders. Many stem cells can be cultured in 2D relatively easily using tissue culture plastic. However, many of these cult...

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Year of Publication:2021
Language:English
Physical Description:1 electronic resource (186 p.)
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100 1 |a Ylostalo, Joni H.  |4 edt 
245 1 0 |a 3D Stem Cell Culture 
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520 |a Recently, stem cells have been drawing increasing interest in basic and translational research that aims to understand stem cell biology and generate new therapies for various disorders. Many stem cells can be cultured in 2D relatively easily using tissue culture plastic. However, many of these cultures do not represent the natural conditions of stem cells in the body. In the body, microenvironments include numerous supporting cells and molecules. Therefore, researchers and clinicians have sought ideal stem cell preparations for basic research and clinical applications, which may be attainable through 3D culture of stem cells. The 3D cultures mimic the conditions of the natural environment of stem cells better, as cells in 3D cultures exhibit many unique and desirable characteristics that could be beneficial for therapeutic interventions. 3D stem cell cultures may employ supporting structures, such as various matrices or scaffolds, in addition to stem cells, to support complex structures. This book brings together recent research on 3D cultures of various stem cells to increase the basic understanding of stem cell culture techniques and also to highlight stem cell preparations for possible novel therapeutic applications. 
546 |a English 
650 7 |a Research & information: general  |2 bicssc 
650 7 |a Biology, life sciences  |2 bicssc 
653 |a hematopoiesis 
653 |a hematopoietic stem cells 
653 |a stem cell culture 
653 |a 2D culture 
653 |a 3D culture 
653 |a embryonic stem cells 
653 |a three-dimensional 
653 |a self-assembling scaffold 
653 |a pluripotency 
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653 |a expansion 
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653 |a hiPSC-derived neural progenitors 
653 |a cerebral cortex 
653 |a carcinogen 
653 |a protein phosphatase 2A (PP2A) 
653 |a intestinal tumor 
653 |a intestinal organoid 
653 |a Lgr5+ crypt stem cell 
653 |a mouse embryonic stem cell 
653 |a differentiation protocol 
653 |a ureteric bud progenitor cells 
653 |a 3D kidney organoids 
653 |a intestinal organoids 
653 |a canine intestine 
653 |a differentiation 
653 |a organoid culture 
653 |a induced pluripotent stem cells 
653 |a neurospheres 
653 |a neurite outgrowth 
653 |a neurotoxicity 
653 |a hBM-MSCs 
653 |a cytokines 
653 |a tenogenic markers 
653 |a cyclic strain 
653 |a 3D microenvironment 
653 |a PLGA carriers 
653 |a bioreactor 
653 |a cardiac microtissues 
653 |a iPSC-derived cardiomyocytes 
653 |a cardiac fibroblasts 
653 |a cardiac fibrosis 
653 |a cardiac rhythm 
653 |a TGF-β signalling 
653 |a drug screening 
653 |a in vitro model 
653 |a stem cell 
653 |a 3D 
653 |a culture condition 
653 |a regenerative medicine 
653 |a scaffold 
653 |a organoid 
653 |a adipose tissue-derived mesenchymal stem cells 
653 |a stromal vascular fraction 
653 |a platelet rich plasma 
653 |a platelet concentrates 
653 |a veterinary regenerative medicine 
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700 1 |a Ylostalo, Joni H.  |4 oth 
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