Intrinsically Disordered Proteins and Chronic Diseases
This book is an embodiment of a series of articles that were published as part of a Special Issue of Biomolecules. It is dedicated to exploring the role of intrinsically disordered proteins (IDPs) in various chronic diseases. The main goal of the articles is to describe recent progress in elucidatin...
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| Year of Publication: | 2021 |
| Language: | English |
| Physical Description: | 1 electronic resource (224 p.) |
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(CKB)5400000000045873 (oapen)https://directory.doabooks.org/handle/20.500.12854/76537 (EXLCZ)995400000000045873 |
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Kulkarni, Prakash edt Intrinsically Disordered Proteins and Chronic Diseases Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021 1 electronic resource (224 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier This book is an embodiment of a series of articles that were published as part of a Special Issue of Biomolecules. It is dedicated to exploring the role of intrinsically disordered proteins (IDPs) in various chronic diseases. The main goal of the articles is to describe recent progress in elucidating the mechanisms by which IDPs cause various human diseases, such as cancer, cardiovascular disease, amyloidosis, neurodegenerative diseases, diabetes, and genetic diseases, to name a few. Contributed by leading investigators in the field, this compendium serves as a valuable resource for researchers, clinicians as well as postdoctoral fellows and graduate students English Research & information: general bicssc IDP fuzzy interactions protein complementation assays split-GFP reassembly kinetics membraneless organelles optical tweezer liquid-liquid phase separation protein diffusion depletion interaction entropic force low-complexity sequences intrinsically disordered proteins PAGE4 conformational plasticity order-disorder transition phosphorylation intrinsic disordered protein extremely fuzzy complex protein interaction binding mechanism tumor protein p53 mouse double minute 2 mouse double minute 4 Kinase-inducible domain interacting domain phosphomimetics nuclear magnetic resonance transient secondary structure COR15A Late embryogenesis abundant Trifluoroethanol Nuclear magnetic resonance intrinsically disordered regions functional segments disease-related proteins protein-protein interaction subcellular location glucocorticoid receptor intrinsically disordered transactivation activity gene regulation coactivators microtubule associated protein tau intrinsically disordered protein dynamic configuration free energy landscape microtubules electrostatics diffusion protein structure prediction molecular modelling molecular dynamics tau-microtubule association conformational ensemble replica exchange molecular dynamics drug design 3-0365-1262-4 3-0365-1263-2 Uversky, Vladimir N. edt Kulkarni, Prakash oth Uversky, Vladimir N. oth |
| language |
English |
| format |
eBook |
| author2 |
Uversky, Vladimir N. Kulkarni, Prakash Uversky, Vladimir N. |
| author_facet |
Uversky, Vladimir N. Kulkarni, Prakash Uversky, Vladimir N. |
| author2_variant |
p k pk v n u vn vnu |
| author2_role |
HerausgeberIn Sonstige Sonstige |
| title |
Intrinsically Disordered Proteins and Chronic Diseases |
| spellingShingle |
Intrinsically Disordered Proteins and Chronic Diseases |
| title_full |
Intrinsically Disordered Proteins and Chronic Diseases |
| title_fullStr |
Intrinsically Disordered Proteins and Chronic Diseases |
| title_full_unstemmed |
Intrinsically Disordered Proteins and Chronic Diseases |
| title_auth |
Intrinsically Disordered Proteins and Chronic Diseases |
| title_new |
Intrinsically Disordered Proteins and Chronic Diseases |
| title_sort |
intrinsically disordered proteins and chronic diseases |
| publisher |
MDPI - Multidisciplinary Digital Publishing Institute |
| publishDate |
2021 |
| physical |
1 electronic resource (224 p.) |
| isbn |
3-0365-1262-4 3-0365-1263-2 |
| illustrated |
Not Illustrated |
| work_keys_str_mv |
AT kulkarniprakash intrinsicallydisorderedproteinsandchronicdiseases AT uverskyvladimirn intrinsicallydisorderedproteinsandchronicdiseases |
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n |
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(CKB)5400000000045873 (oapen)https://directory.doabooks.org/handle/20.500.12854/76537 (EXLCZ)995400000000045873 |
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Intrinsically Disordered Proteins and Chronic Diseases |
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