Plasma in Cancer Treatment
In the last decade, research on cold atmospheric plasma (CAP) has significantly advanced our understanding of the effect of CAP on cancer cells and their potential for cancer treatment. This effect is due to the reactive oxygen and nitrogen species (RONS) created by plasma. This has been demonstrate...
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| Year of Publication: | 2021 |
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Bogaerts, Annemie edt Plasma in Cancer Treatment Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021 1 electronic resource (358 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier In the last decade, research on cold atmospheric plasma (CAP) has significantly advanced our understanding of the effect of CAP on cancer cells and their potential for cancer treatment. This effect is due to the reactive oxygen and nitrogen species (RONS) created by plasma. This has been demonstrated for different cancer cell lines and the first clinical trials showed promising results. In addition, plasma could be combined with other treatments—such as immunotherapy—to boost its anticancer activity. The addition of new research tools to study the response of cancer cells to CAP—such as 3D in vitro, in ovo, and in vivo models and in silico approaches—as well as the use of -OMICS technologies could aid in unravelling the underlying mechanisms of CAP in cancer treatment. In order to progress towards widespread clinical application of CAP, an integrated study of the multidimensional effect of CAP in cancer treatment is essential. In this book, reviews and original research papers are published that provide new insights into the mechanisms of cold atmospheric plasma in cancer treatment, based on in vitro and in vivo experiments, clinical studies, as well as computer modeling. English Medicine bicssc cell adhesion plasma medicine oncology cold atmospheric plasma selectivity plasma-treated liquid dielectric barrier discharge pancreatic cancer pancreatic stellate cells immunogenic cell death dendritic cells cell communication extracellular matrix (ECM) reactive oxygen and nitrogen species (ROS) tumour microenvironment (TME) extracellular vesicles communication junctions three-dimensional in vitro culture models apoptosis breast cancer genome-wide expression reactive oxygen species anticancer drugs screening tumor spheroids combination therapy kINPen reactive oxygen and nitrogen species ROS cancer non-thermal atmospheric pressure plasma (NTP) indirect treatment plasma-treated phosphate-buffered saline electroporation electric pulses pulsed electric field amplitude melanoma long-lived reactive species bone cancer osteosarcoma reactive species plasma-activated liquid Ringer's saline organotypic model nonthermal biocompatible plasma soft jet plasma human glioblastoma p38/MAPK pathway tissue penetration non-thermal plasma non-invasive plasma treatment (NIPP) cervical intraepithelial neoplasia (CIN) Raman imaging Raman microspectroscopy Plasma lipid interactions cold physical plasma radiation therapy radio-frequency discharge PARP-inhibitor olaparib DNA-damage gold quantum dots plasma nanomaterials cellular uptake invasiveness cold atmospheric pressure plasma plasma-activated Ringer's lactate solution ovarian cancer cytotoxicity plasma-activated liquids multicellular tumor spheroids long-lived reactive oxygen and nitrogen species high frequency electrosurgery plasma treatment cold atmospheric plasma (CAP) free radicals cancer selectivity cervical cancer treatment cervical intraepithelial neoplasia cholangiocarcinoma cold plasma innovative therapy tumor cells macrophages plasma selectivity plasma jet 3-0365-1209-8 3-0365-1208-X Privat-Maldonado, Angela edt Bogaerts, Annemie oth Privat-Maldonado, Angela oth |
| language |
English |
| format |
eBook |
| author2 |
Privat-Maldonado, Angela Bogaerts, Annemie Privat-Maldonado, Angela |
| author_facet |
Privat-Maldonado, Angela Bogaerts, Annemie Privat-Maldonado, Angela |
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a b ab a p m apm |
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HerausgeberIn Sonstige Sonstige |
| title |
Plasma in Cancer Treatment |
| spellingShingle |
Plasma in Cancer Treatment |
| title_full |
Plasma in Cancer Treatment |
| title_fullStr |
Plasma in Cancer Treatment |
| title_full_unstemmed |
Plasma in Cancer Treatment |
| title_auth |
Plasma in Cancer Treatment |
| title_new |
Plasma in Cancer Treatment |
| title_sort |
plasma in cancer treatment |
| publisher |
MDPI - Multidisciplinary Digital Publishing Institute |
| publishDate |
2021 |
| physical |
1 electronic resource (358 p.) |
| isbn |
3-0365-1209-8 3-0365-1208-X |
| illustrated |
Not Illustrated |
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