Drug Metabolism/Transport and Pharmacokinetics
This book serves to highlight the pharmacokinetics/drug–drug interactions and mechanistic understanding in relation to the drug-metabolizing enzymes and drug transporters.This book presents a series of drug metabolism and transport mechanisms that govern the pharmacokinetic features of therapeutic d...
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| Year of Publication: | 2021 |
| Language: | English |
| Physical Description: | 1 electronic resource (232 p.) |
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(CKB)5400000000045325 (oapen)https://directory.doabooks.org/handle/20.500.12854/77070 (EXLCZ)995400000000045325 |
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Song, Im-Sook edt Drug Metabolism/Transport and Pharmacokinetics Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021 1 electronic resource (232 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier This book serves to highlight the pharmacokinetics/drug–drug interactions and mechanistic understanding in relation to the drug-metabolizing enzymes and drug transporters.This book presents a series of drug metabolism and transport mechanisms that govern the pharmacokinetic features of therapeutic drugs as well as natural herbal medicines. It also covers the pharmacokinetic interactions caused by inhibiting or inducing the metabolic or transport activities under disease states or the coadministration of potential inhibitors. It also deals with microenvironmental pharmacokinetic profiles as well as population pharmacokinetics, which gives new insights regarding the pharmacokinetic features with regard to drug metabolism and transporters. English Medicine bicssc Pharmaceutical industries bicssc tofacitinib dose-dependent pharmacokinetics hepatic and intestinal first-pass effect rats catalposide in vitro human metabolism UDP-glucuronosyltransferase sulfotransferase carboxylesterase celecoxib drug–drug interaction fluorescence HPLC metabolism repaglinide HSG4112 anti-obesity agent stereoselectivity pharmacokinetics compound K protopanaxadiol (PPD) biliary excretion intestinal metabolism Carthamus tinctorius extract notoginseng total saponins comparative pharmacokinetic study large volume direct injection compatibility mechanism mertansine human hepatocytes cytochrome P450 UDP-glucuronosyltransferases sodium-glucose cotransporter 2 (SGLT2) inhibitors DWP16001 kidney distribution inhibition mode diabetes transporter-enzyme interplay influx transporter efflux transporter physiologically based pharmacokinetic model cytochrome P450 enzymes tiropramide healthy Korean subjects modeling population pharmacokinetic quercetin breast cancer resistance protein inhibitor prazosin sulfasalazine kinetic analysis food–drug interactions Caco-2 EpiIntestinal first-pass P-gp BCRP drug transporter CYP3A4 oral availability automatization drug absorption drug dosing head-and-neck cancer real-time measurements taxanes tissue engineering UHPLC-MS/MS metformin verapamil drug interaction organic cation transporter 2 renal excretion acute renal failure gentamicin cisplatin hepatic CYP3A1(23) creatinine clearance renal clearance nonrenal clearance 3-0365-2459-2 3-0365-2458-4 Song, Im-Sook oth |
| language |
English |
| format |
eBook |
| author2 |
Song, Im-Sook |
| author_facet |
Song, Im-Sook |
| author2_variant |
i s s iss |
| author2_role |
Sonstige |
| title |
Drug Metabolism/Transport and Pharmacokinetics |
| spellingShingle |
Drug Metabolism/Transport and Pharmacokinetics |
| title_full |
Drug Metabolism/Transport and Pharmacokinetics |
| title_fullStr |
Drug Metabolism/Transport and Pharmacokinetics |
| title_full_unstemmed |
Drug Metabolism/Transport and Pharmacokinetics |
| title_auth |
Drug Metabolism/Transport and Pharmacokinetics |
| title_new |
Drug Metabolism/Transport and Pharmacokinetics |
| title_sort |
drug metabolism/transport and pharmacokinetics |
| publisher |
MDPI - Multidisciplinary Digital Publishing Institute |
| publishDate |
2021 |
| physical |
1 electronic resource (232 p.) |
| isbn |
3-0365-2459-2 3-0365-2458-4 |
| illustrated |
Not Illustrated |
| work_keys_str_mv |
AT songimsook drugmetabolismtransportandpharmacokinetics |
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n |
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(CKB)5400000000045325 (oapen)https://directory.doabooks.org/handle/20.500.12854/77070 (EXLCZ)995400000000045325 |
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cr |
| is_hierarchy_title |
Drug Metabolism/Transport and Pharmacokinetics |
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noLinkedField |
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