Tumor angiogenesis / / edited by Sophia Ra.
Tumor angiogenesis is the main process responsible for the formation of new blood vessels that promote tumor growth and metastasis. This process is driven by potent pro-angiogenic factors that are predominant in the tumor environment and are produced by both malignant cells and the host cells recrui...
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Place / Publishing House: | Rijeka, Croatia : : IntechOpen,, [2012] ©2012 |
Year of Publication: | 2012 |
Language: | English |
Physical Description: | 1 online resource (308 pages) :; illustrations |
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(CKB)4970000000097614 (NjHacI)994970000000097614 (oapen)https://directory.doabooks.org/handle/20.500.12854/65578 (EXLCZ)994970000000097614 |
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Ran, Sophia edt Tumor angiogenesis / edited by Sophia Ra. IntechOpen 2012 Rijeka, Croatia : IntechOpen, [2012] ©2012 1 online resource (308 pages) : illustrations text txt rdacontent computer c rdamedia online resource cr rdacarrier Description based on: online resource; title from PDF information screen (InTech, viewed October 12, 2022). Includes bibliographical references. Tumor angiogenesis is the main process responsible for the formation of new blood vessels that promote tumor growth and metastasis. This process is driven by potent pro-angiogenic factors that are predominant in the tumor environment and are produced by both malignant cells and the host cells recruited to the tumor site. Tumor environment is characterized by the imbalance between pro-angiogenic and anti-angiogenic factors, which drives the construction of numerous but structurally defective vessels. These poorly perfused and abnormal vessels significantly contribute to the tumor pathology not only by supporting the expansion of the tumor mass but also by promoting chronic inflammation, enhancing thrombosis, impeding drug delivery, and disseminating tumor cells. These problems associated with tumor vasculature continue to attract great attention of scientists and clinicians interested in advancing the understanding of tumor biology and development of new drugs. This book complies a series of reviews that cover a broad spectrum of current topics related to the pathology of tumor blood vessels including mechanisms inducing new vessels, identification of new targets for inhibition of tumor angiogenesis, and potential clinical use of known and novel anti-angiogenic therapies. The book provides an update on tumor angiogenesis that could be useful for oncologists, cancer researchers and biologists with interests in vascular and endothelial cell behavior in the context of cancer. English Tumors Growth. Oncology 953-51-0009-2 Ra, Sophia, editor. |
language |
English |
format |
eBook |
author2 |
Ra, Sophia, |
author_facet |
Ra, Sophia, |
author2_variant |
s r sr s r sr |
author2_role |
TeilnehmendeR |
title |
Tumor angiogenesis / |
spellingShingle |
Tumor angiogenesis / |
title_full |
Tumor angiogenesis / edited by Sophia Ra. |
title_fullStr |
Tumor angiogenesis / edited by Sophia Ra. |
title_full_unstemmed |
Tumor angiogenesis / edited by Sophia Ra. |
title_auth |
Tumor angiogenesis / |
title_new |
Tumor angiogenesis / |
title_sort |
tumor angiogenesis / |
publisher |
IntechOpen IntechOpen, |
publishDate |
2012 |
physical |
1 online resource (308 pages) : illustrations |
isbn |
953-51-6795-2 953-51-0009-2 |
callnumber-first |
R - Medicine |
callnumber-subject |
RC - Internal Medicine |
callnumber-label |
RC254 |
callnumber-sort |
RC 3254.6 T866 42012 |
illustrated |
Illustrated |
dewey-hundreds |
600 - Technology |
dewey-tens |
610 - Medicine & health |
dewey-ones |
616 - Diseases |
dewey-full |
616.992 |
dewey-sort |
3616.992 |
dewey-raw |
616.992 |
dewey-search |
616.992 |
work_keys_str_mv |
AT ransophia tumorangiogenesis AT rasophia tumorangiogenesis |
status_str |
n |
ids_txt_mv |
(CKB)4970000000097614 (NjHacI)994970000000097614 (oapen)https://directory.doabooks.org/handle/20.500.12854/65578 (EXLCZ)994970000000097614 |
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is_hierarchy_title |
Tumor angiogenesis / |
author2_original_writing_str_mv |
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