Adult stem cell niches

Tissue-specific stem cells have the capacity to self-renew and differentiate into several types of functional cells that replenish lost cells throughout an organism?s lifetime. Studies on stem cells from diverse systems have shown that stem cell function is controlled by extracellular cues from the...

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TeilnehmendeR:
Place / Publishing House:[Place of publication not identified] : : IntechOpen,, 2014.
©2014
Year of Publication:2014
Language:English
Physical Description:1 online resource (332 pages)
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spelling Wislet-Gendebien, Sabine edt
Adult stem cell niches
IntechOpen 2014
[Place of publication not identified] : IntechOpen, 2014.
©2014
1 online resource (332 pages)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Open access Unrestricted online access star
Tissue-specific stem cells have the capacity to self-renew and differentiate into several types of functional cells that replenish lost cells throughout an organism?s lifetime. Studies on stem cells from diverse systems have shown that stem cell function is controlled by extracellular cues from the niche and by intrinsic genetic programs within the stem cell. The objectives of this book would be to review the molecular mechanisms that mediate the balanced response of stem cells to the needs of the organisms. Likewise, niches have also been linked to pathologies, by imposing aberrant function on stem cells or other targets. Therefore, the second objective of this book would be to highligh the molecular dysregulation of niche biology leading to the disease. The third objective would be to review the therapeutical targets described within stem cell niches.
English
SCIENCE / Life Sciences / Cell Biology. bisacsh
Cellular biology (cytology)
953-51-1718-1
Wislet-Gendebien, Sabine, editor
language English
format eBook
author2 Wislet-Gendebien, Sabine,
author_facet Wislet-Gendebien, Sabine,
author2_variant s w g swg
s w g swg
author2_role TeilnehmendeR
title Adult stem cell niches
spellingShingle Adult stem cell niches
title_full Adult stem cell niches
title_fullStr Adult stem cell niches
title_full_unstemmed Adult stem cell niches
title_auth Adult stem cell niches
title_new Adult stem cell niches
title_sort adult stem cell niches
publisher IntechOpen
IntechOpen,
publishDate 2014
physical 1 online resource (332 pages)
isbn 953-51-7220-4
953-51-1718-1
illustrated Illustrated
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carrierType_str_mv cr
is_hierarchy_title Adult stem cell niches
author2_original_writing_str_mv noLinkedField
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