Mitogen Activated Protein Kinases : Functions in Signal Transduction and Human Diseases

Mitogen Activated Protein Kinases : Functions in Signal Transduction and Human Diseases

Mitogen-activated protein kinases (MAPK) are a large family of enzymes that function as signal transducers to regulate a diverse range of physiological responses. However, signaling via extracellular signal-regulated kinase (ERK), c-Jun amino terminal kinase (JNK), and p38 MAPK also underpin many di...

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HerausgeberIn:
Nikolic-Paterson, David
Sonstige:
Tikkanen, Ritva
Nikolic-Paterson, David
Year of Publication:2020
Language:English
Physical Description:1 electronic resource (276 p.)
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(oapen)https://directory.doabooks.org/handle/20.500.12854/68643
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record_format marc
spelling Tikkanen, Ritva edt
Mitogen Activated Protein Kinases Functions in Signal Transduction and Human Diseases
Mitogen Activated Protein Kinases
Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
1 electronic resource (276 p.)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Mitogen-activated protein kinases (MAPK) are a large family of enzymes that function as signal transducers to regulate a diverse range of physiological responses. However, signaling via extracellular signal-regulated kinase (ERK), c-Jun amino terminal kinase (JNK), and p38 MAPK also underpin many disease processes. This Special Issue provides new insights into how MAPK signaling contributes to specific pathological processes across a range of conditions, including disorders of lung development, type 2 diabetes, proliferative skin diseases, cardiovascular diseases, and neurological diseases.
English
Research & information: general bicssc
Biology, life sciences bicssc
Rabdosia inflexa
inflammation
gastric ulcer
cytokines
MAPK
NF-κB
extracellular signal-regulated kinases 1/2
hyperoxia
bronchopulmonary dysplasia
HPAECs
angiogenesis
cell cycle
SIRT1
oxidative stress
psoriasis
antimicrobial peptide
cecropin A
tight junction protein
MEK/ERK signaling
porcine intestinal epithelial cell
extracellular signal-regulated kinase 5 (ERK5)
Kv4.2
PC12 cells
infantile myofibromatosis
receptor tyrosine kinases
platelet-derived growth factor receptor
protein kinase inhibitors
sunitinib
erlotinib
FR180204
U0126
targeted therapy
apoptosis
ERK1/2
JNKs
mitochondrial dysfunction
neurodegeneration
neuro-inflammation
p38 MAPKs
Parkinson's disease
mitogen-activated protein kinases (MAPKs)
MAPK kinetics
osteoclast differentiation
bone remodeling
DAPK
ERK
p38
JNK
mitogen-activated protein kinase pathway (MAPK pathway)
protein tyrosine phosphatase interacting protein 51 (PTPIP51)
protein-protein interaction (PPI)
cancer signaling
SR
CR
Compatibility
T2DM
metabolic profiling
MAPK/PI3K/Akt signaling pathway
reactive oxygen species
PTPN6
SRC
DOK4
MKK4
MKK7
p53
DUSP1
SIRT2
atherosclerosis
aortic valve sclerosis
aortic valve stenosis
naphthalimide-metal complex conjugates
N-heterocyclic carbene
mitochondria
ROS
p38 MAPK
cancer
FGF-induced signaling
FRS2
phosphorylation
downregulation
3-03928-070-8
3-03928-071-6
Nikolic-Paterson, David edt
Tikkanen, Ritva oth
Nikolic-Paterson, David oth
language English
format eBook
author2 Nikolic-Paterson, David
Tikkanen, Ritva
Nikolic-Paterson, David
author_facet Nikolic-Paterson, David
Tikkanen, Ritva
Nikolic-Paterson, David
author2_variant r t rt
d n p dnp
author2_role HerausgeberIn
Sonstige
Sonstige
title Mitogen Activated Protein Kinases Functions in Signal Transduction and Human Diseases
spellingShingle Mitogen Activated Protein Kinases Functions in Signal Transduction and Human Diseases
title_sub Functions in Signal Transduction and Human Diseases
title_full Mitogen Activated Protein Kinases Functions in Signal Transduction and Human Diseases
title_fullStr Mitogen Activated Protein Kinases Functions in Signal Transduction and Human Diseases
title_full_unstemmed Mitogen Activated Protein Kinases Functions in Signal Transduction and Human Diseases
title_auth Mitogen Activated Protein Kinases Functions in Signal Transduction and Human Diseases
title_alt Mitogen Activated Protein Kinases
title_new Mitogen Activated Protein Kinases
title_sort mitogen activated protein kinases functions in signal transduction and human diseases
publisher MDPI - Multidisciplinary Digital Publishing Institute
publishDate 2020
physical 1 electronic resource (276 p.)
isbn 3-03928-070-8
3-03928-071-6
illustrated Not Illustrated
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