Human skin cancer, potential biomarkers and therapeutic targets / / edited by Miroslav Blumenberg.

Skin cancers, basal and squamous cell carcinomas, malignant melanomas, and Merkel cell carcinomas, constitute arguably the most common and increasingly prevalent human neoplasms. Here we discuss the epigenetic changes in DNA and chromatin, which are increasingly associated with melanoma. Several cha...

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Place / Publishing House:Rijeka, Croatia : : IntechOpen,, [2016]
©2016
Year of Publication:2016
Language:English
Physical Description:1 online resource (150 pages)
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Human skin cancer, potential biomarkers and therapeutic targets / edited by Miroslav Blumenberg.
IntechOpen 2016
Rijeka, Croatia : IntechOpen, [2016]
©2016
1 online resource (150 pages)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Description based on: online resource; title from PDF information screen (InTech, viewed October 18, 2022).
Skin cancers, basal and squamous cell carcinomas, malignant melanomas, and Merkel cell carcinomas, constitute arguably the most common and increasingly prevalent human neoplasms. Here we discuss the epigenetic changes in DNA and chromatin, which are increasingly associated with melanoma. Several chapters focus on the posttranscriptional modification of the proteins at the melanocyte cell surface, their role in tumorigenesis, and their potential as therapeutic targets. Specifically, extracellular modifications of integrins, glycosylation of cell surface proteins, and changes of cadherins are presented. In a very interesting approach, a potential to target the mitochondria of melanoma cells is investigated. In conclusion, this volume presents various aspects of human skin cancers, components of the large worldwide effort to combat and eradicate this growing health concern.
English
Skin Cancer.
Medicine
Oncology
Dermatological Oncology
Health Sciences
953-51-2710-1
Blumenberg, Miroslav Lj., editor.
language English
format eBook
author Miroslav Blumenberg
spellingShingle Miroslav Blumenberg
Human skin cancer, potential biomarkers and therapeutic targets /
author_facet Miroslav Blumenberg
Blumenberg, Miroslav Lj.,
author_variant m b mb
author2 Blumenberg, Miroslav Lj.,
author2_variant m l b ml mlb
author2_role TeilnehmendeR
author_sort Miroslav Blumenberg
title Human skin cancer, potential biomarkers and therapeutic targets /
title_full Human skin cancer, potential biomarkers and therapeutic targets / edited by Miroslav Blumenberg.
title_fullStr Human skin cancer, potential biomarkers and therapeutic targets / edited by Miroslav Blumenberg.
title_full_unstemmed Human skin cancer, potential biomarkers and therapeutic targets / edited by Miroslav Blumenberg.
title_auth Human skin cancer, potential biomarkers and therapeutic targets /
title_new Human skin cancer, potential biomarkers and therapeutic targets /
title_sort human skin cancer, potential biomarkers and therapeutic targets /
publisher IntechOpen
IntechOpen,
publishDate 2016
physical 1 online resource (150 pages)
isbn 953-51-7317-0
953-51-2711-X
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dewey-tens 610 - Medicine & health
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