Prion : : an overview / / edited by Yusuf Tutar.
Protein aggregation causes malfunction in several biochemical processes. Genetic and spontaneous formations of these transmissible spongiform encephalopathies are fatal to humans and animals. Conformational change of normal form of the protein to misfolded form causes its accumulation. The misfolded...
Saved in:
| : | |
|---|---|
| TeilnehmendeR: | |
| Place / Publishing House: | Rijeka, Croatia : : IntechOpen,, [2017] ©2017 |
| Year of Publication: | 2017 |
| Language: | English |
| Physical Description: | 1 online resource (238 pages) |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| id |
993545378504498 |
|---|---|
| ctrlnum |
(CKB)4970000000099340 (NjHacI)994970000000099340 (oapen)https://directory.doabooks.org/handle/20.500.12854/56991 (EXLCZ)994970000000099340 |
| collection |
bib_alma |
| record_format |
marc |
| spelling |
Yusuf Tutar auth Prion : an overview / edited by Yusuf Tutar. Prion Prion â An Overview IntechOpen 2017 Rijeka, Croatia : IntechOpen, [2017] ©2017 1 online resource (238 pages) text txt rdacontent computer c rdamedia online resource cr rdacarrier Description based on: online resource; title from PDF information screen (InTech, viewed October 6, 2022). Protein aggregation causes malfunction in several biochemical processes. Genetic and spontaneous formations of these transmissible spongiform encephalopathies are fatal to humans and animals. Conformational change of normal form of the protein to misfolded form causes its accumulation. The misfolded infectious protein agent forms the pathogenesis of the disease. This book presents pathology of the disease along with current knowledge of the structure-activity mechanism in the first two sections. Dyshomeostasis of metals is implicated in the pathogenesis of prions, and this influence is discussed further to understand the prion mechanism. Genetic resistance and immunobiology of the disease are elaborated in the following section. Finally, a computational study on the dynamics of the prion propagation provides a structural basis of the mechanism. English Proteins. Medicine Internal Medicine Infectious Diseases Health Sciences 953-51-3001-3 Tutar, Yusuf, editor. |
| language |
English |
| format |
eBook |
| author |
Yusuf Tutar |
| spellingShingle |
Yusuf Tutar Prion : an overview / |
| author_facet |
Yusuf Tutar Tutar, Yusuf, |
| author_variant |
y t yt |
| author2 |
Tutar, Yusuf, |
| author2_variant |
y t yt |
| author2_role |
TeilnehmendeR |
| author_sort |
Yusuf Tutar |
| title |
Prion : an overview / |
| title_sub |
an overview / |
| title_full |
Prion : an overview / edited by Yusuf Tutar. |
| title_fullStr |
Prion : an overview / edited by Yusuf Tutar. |
| title_full_unstemmed |
Prion : an overview / edited by Yusuf Tutar. |
| title_auth |
Prion : an overview / |
| title_alt |
Prion Prion â An Overview |
| title_new |
Prion : |
| title_sort |
prion : an overview / |
| publisher |
IntechOpen IntechOpen, |
| publishDate |
2017 |
| physical |
1 online resource (238 pages) |
| isbn |
953-51-7349-9 953-51-3002-1 953-51-3001-3 |
| callnumber-first |
Q - Science |
| callnumber-subject |
QP - Physiology |
| callnumber-label |
QP551 |
| callnumber-sort |
QP 3551 P756 42017 |
| illustrated |
Not Illustrated |
| dewey-hundreds |
500 - Science |
| dewey-tens |
540 - Chemistry |
| dewey-ones |
547 - Organic chemistry |
| dewey-full |
547.75 |
| dewey-sort |
3547.75 |
| dewey-raw |
547.75 |
| dewey-search |
547.75 |
| work_keys_str_mv |
AT yusuftutar prionanoverview AT tutaryusuf prionanoverview AT yusuftutar prion AT tutaryusuf prion AT yusuftutar prionaanoverview AT tutaryusuf prionaanoverview |
| status_str |
n |
| ids_txt_mv |
(CKB)4970000000099340 (NjHacI)994970000000099340 (oapen)https://directory.doabooks.org/handle/20.500.12854/56991 (EXLCZ)994970000000099340 |
| carrierType_str_mv |
cr |
| is_hierarchy_title |
Prion : an overview / |
| author2_original_writing_str_mv |
noLinkedField |
| _version_ |
1796649061551439872 |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>00945nam a2200301 i 4500</leader><controlfield tag="001">993545378504498</controlfield><controlfield tag="005">20221006181329.0</controlfield><controlfield tag="006">m o d </controlfield><controlfield tag="007">cr |||||||||||</controlfield><controlfield tag="008">221006s2017 ci o 000 0 eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">953-51-7349-9</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">953-51-3002-1</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(CKB)4970000000099340</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(NjHacI)994970000000099340</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(oapen)https://directory.doabooks.org/handle/20.500.12854/56991</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(EXLCZ)994970000000099340</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">NjHacI</subfield><subfield code="b">eng</subfield><subfield code="e">rda</subfield><subfield code="c">NjHacl</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="050" ind1=" " ind2="4"><subfield code="a">QP551</subfield><subfield code="b">.P756 2017</subfield></datafield><datafield tag="082" ind1="0" ind2="4"><subfield code="a">547.75</subfield><subfield code="2">23</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Yusuf Tutar</subfield><subfield code="4">auth</subfield></datafield><datafield tag="245" ind1="0" ind2="0"><subfield code="a">Prion :</subfield><subfield code="b">an overview /</subfield><subfield code="c">edited by Yusuf Tutar.</subfield></datafield><datafield tag="246" ind1=" " ind2=" "><subfield code="a">Prion</subfield></datafield><datafield tag="246" ind1=" " ind2=" "><subfield code="a">Prion â An Overview</subfield></datafield><datafield tag="260" ind1=" " ind2=" "><subfield code="b">IntechOpen</subfield><subfield code="c">2017</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Rijeka, Croatia :</subfield><subfield code="b">IntechOpen,</subfield><subfield code="c">[2017]</subfield></datafield><datafield tag="264" ind1=" " ind2="4"><subfield code="c">©2017</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 online resource (238 pages)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">computer</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">online resource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="588" ind1=" " ind2=" "><subfield code="a">Description based on: online resource; title from PDF information screen (InTech, viewed October 6, 2022).</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Protein aggregation causes malfunction in several biochemical processes. Genetic and spontaneous formations of these transmissible spongiform encephalopathies are fatal to humans and animals. Conformational change of normal form of the protein to misfolded form causes its accumulation. The misfolded infectious protein agent forms the pathogenesis of the disease. This book presents pathology of the disease along with current knowledge of the structure-activity mechanism in the first two sections. Dyshomeostasis of metals is implicated in the pathogenesis of prions, and this influence is discussed further to understand the prion mechanism. Genetic resistance and immunobiology of the disease are elaborated in the following section. Finally, a computational study on the dynamics of the prion propagation provides a structural basis of the mechanism.</subfield></datafield><datafield tag="546" ind1=" " ind2=" "><subfield code="a">English</subfield></datafield><datafield tag="650" ind1=" " ind2="0"><subfield code="a">Proteins.</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Medicine</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Internal Medicine</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Infectious Diseases</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Health Sciences</subfield></datafield><datafield tag="776" ind1=" " ind2=" "><subfield code="z">953-51-3001-3</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Tutar, Yusuf,</subfield><subfield code="e">editor.</subfield></datafield><datafield tag="906" ind1=" " ind2=" "><subfield code="a">BOOK</subfield></datafield><datafield tag="ADM" ind1=" " ind2=" "><subfield code="b">2023-02-22 20:03:35 Europe/Vienna</subfield><subfield code="f">system</subfield><subfield code="c">marc21</subfield><subfield code="a">2019-04-13 22:04:18 Europe/Vienna</subfield><subfield code="g">false</subfield></datafield><datafield tag="AVE" ind1=" " ind2=" "><subfield code="i">DOAB Directory of Open Access Books</subfield><subfield code="P">DOAB Directory of Open Access Books</subfield><subfield code="x">https://eu02.alma.exlibrisgroup.com/view/uresolver/43ACC_OEAW/openurl?u.ignore_date_coverage=true&portfolio_pid=5351650820004498&Force_direct=true</subfield><subfield code="Z">5351650820004498</subfield><subfield code="b">Available</subfield><subfield code="8">5351650820004498</subfield></datafield></record></collection> |