Antiviral Agents

Open Access

Antiviral Agents

Antiviral agents are used for the treatment of viral diseases. Antiviral drugs have been successfully developed and used clinically for a limited number of important human viral diseases notably caused by human immunodeficiency virus (HIV), hepatitis C virus (HCV), hepatitis B virus (HBV), herpes, a...

Full description

Saved in:
Bibliographic Details
Sonstige:
Adamson, Catherine
Year of Publication:2020
Language:English
Physical Description:1 electronic resource (386 p.)
Tags: Add Tag
No Tags, Be the first to tag this record!
id 993545355504498
ctrlnum (CKB)5400000000043253
(oapen)https://directory.doabooks.org/handle/20.500.12854/68969
(EXLCZ)995400000000043253
collection bib_alma
record_format marc
spelling Adamson, Catherine edt
Antiviral Agents
Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
1 electronic resource (386 p.)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Open access Unrestricted online access star
Antiviral agents are used for the treatment of viral diseases. Antiviral drugs have been successfully developed and used clinically for a limited number of important human viral diseases notably caused by human immunodeficiency virus (HIV), hepatitis C virus (HCV), hepatitis B virus (HBV), herpes, and influenza viruses. Despite the successes of these antiviral drugs, issues with drug resistance and toxicity remain challenging. These challenges are driving research to identify new drug candidates and to investigate novel drug targets to develop new mechanistic drug classes. Antiviral agents are not available against many viruses that cause human disease and economic burdens; in particular, the development of antiviral agents against emerging, re-emerging, and neglected viruses is increasingly becoming a priority. This book includes six review articles that discuss new antiviral strategies. The reviews either discuss advances relating to a specific virus or new therapeutic targets and approaches. The book includes 15 original research articles reporting new antiviral agents against a variety of clinically and economically important viruses and studies into the prevalence or acquisition of drug resistance. Overall, this book is an exciting collection of new research and ideas relating to the development of antiviral agents.
English
Research & information: general bicssc
Biology, life sciences bicssc
Zika virus
nucleoside analogues
antiviral agents
NS5
prodrugs
ProTides
neural stem cells
RNA-dependent RNA polymerase
cytomegalovirus
latent infection
TALEN
Surveyor nuclease mutation detection assay
ie-1 gene
quantitative real-time PCR
Epstein-Barr virus
herpes viruses
lytic gene expression
Burkitt lymphoma cells
clozapine
antipsychotic drug
antiviral drug
enteroviruses
coxsackievirus B4
persistent infection
fluoxetine
resistance
mutations
herpes B virus
macacine herpesvirus-1
genistein
flavonoids
acyclovir
ganciclovir
Plantago asiatica
Clerodendrum trichotomum
RSV
therapeutic effects
acteoside
human antimicrobial peptides
antiviral strategies
defensins
cathelicidins
hepcidins
transferrins
influenza A virus
brevilin A
antiviral
sesquiterpene lactone
replication
PRRSV
polyethylenimine
PEI
virion internalization
endocytosis
HIV
pediatrics
Ethiopia
pre-treatment drug resistance
combination antiretroviral therapy (cART)
dried plasma spots
dried blood spots
sphingolipids
glycosphingolipids
viruses
lipid biosynthesis
flavivirus
Japanese encephalitis virus
furin inhibitor
precursor membrane protein
measles virus
central nervous system
tropism
treatments
porcine reproductive and respiratory syndrome virus
ginsenoside Rg1
antiviral activity
pro-inflammatory factor
NF-κB signaling pathway
acute/latent infection
congenital infection
antiviral agent
therapeutic strategies
nucleic acid-based therapeutic approach
HCMV vaccine
adoptive cell therapy
Rev response element
chemical footprinting
SHAPE
drug discovery
branched peptides
herpesvirus
immediate-early
IE1
IE2
ribozyme
RNA interference
CRISPR/Cas
small molecule
orthohantavirus
phenyl-benzotriazoles
C-FRA
Porcine circovirus type 2
epigallocatechin gallate
heparan sulfate
antiviral effect
virus attachment
microvirin
lectin
human immunodeficiency virus
hepatitis C virus
antiviral inhibitor
non-immunogenic
viral entry
protein drugs
LUMS1
oleanane-type derivatives
influenza A virus (IAV)
virus entry inhibitors
hemagglutinin (HA)
3-03928-953-5
3-03928-954-3
Adamson, Catherine oth
language English
format eBook
author2 Adamson, Catherine
author_facet Adamson, Catherine
author2_variant c a ca
author2_role Sonstige
title Antiviral Agents
spellingShingle Antiviral Agents
title_full Antiviral Agents
title_fullStr Antiviral Agents
title_full_unstemmed Antiviral Agents
title_auth Antiviral Agents
title_new Antiviral Agents
title_sort antiviral agents
publisher MDPI - Multidisciplinary Digital Publishing Institute
publishDate 2020
physical 1 electronic resource (386 p.)
isbn 3-03928-953-5
3-03928-954-3
illustrated Not Illustrated
work_keys_str_mv AT adamsoncatherine antiviralagents
status_str n
ids_txt_mv (CKB)5400000000043253
(oapen)https://directory.doabooks.org/handle/20.500.12854/68969
(EXLCZ)995400000000043253
carrierType_str_mv cr
is_hierarchy_title Antiviral Agents
author2_original_writing_str_mv noLinkedField
_version_ 1796651466696425472
fullrecord <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>06254nam-a2201741z--4500</leader><controlfield tag="001">993545355504498</controlfield><controlfield tag="005">20240125182926.0</controlfield><controlfield tag="006">m o d </controlfield><controlfield tag="007">cr|mn|---annan</controlfield><controlfield tag="008">202105s2020 xx |||||o ||| 0|eng d</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(CKB)5400000000043253</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(oapen)https://directory.doabooks.org/handle/20.500.12854/68969</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(EXLCZ)995400000000043253</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Adamson, Catherine</subfield><subfield code="4">edt</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Antiviral Agents</subfield></datafield><datafield tag="260" ind1=" " ind2=" "><subfield code="a">Basel, Switzerland</subfield><subfield code="b">MDPI - Multidisciplinary Digital Publishing Institute</subfield><subfield code="c">2020</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 electronic resource (386 p.)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">computer</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">online resource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="506" ind1=" " ind2=" "><subfield code="a">Open access</subfield><subfield code="f">Unrestricted online access</subfield><subfield code="2">star</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Antiviral agents are used for the treatment of viral diseases. Antiviral drugs have been successfully developed and used clinically for a limited number of important human viral diseases notably caused by human immunodeficiency virus (HIV), hepatitis C virus (HCV), hepatitis B virus (HBV), herpes, and influenza viruses. Despite the successes of these antiviral drugs, issues with drug resistance and toxicity remain challenging. These challenges are driving research to identify new drug candidates and to investigate novel drug targets to develop new mechanistic drug classes. Antiviral agents are not available against many viruses that cause human disease and economic burdens; in particular, the development of antiviral agents against emerging, re-emerging, and neglected viruses is increasingly becoming a priority. This book includes six review articles that discuss new antiviral strategies. The reviews either discuss advances relating to a specific virus or new therapeutic targets and approaches. The book includes 15 original research articles reporting new antiviral agents against a variety of clinically and economically important viruses and studies into the prevalence or acquisition of drug resistance. Overall, this book is an exciting collection of new research and ideas relating to the development of antiviral agents.</subfield></datafield><datafield tag="546" ind1=" " ind2=" "><subfield code="a">English</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Research &amp; information: general</subfield><subfield code="2">bicssc</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Biology, life sciences</subfield><subfield code="2">bicssc</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Zika virus</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">nucleoside analogues</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">antiviral agents</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">NS5</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">prodrugs</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ProTides</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">neural stem cells</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">RNA-dependent RNA polymerase</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cytomegalovirus</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">latent infection</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">TALEN</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Surveyor nuclease mutation detection assay</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ie-1 gene</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">quantitative real-time PCR</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Epstein-Barr virus</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">herpes viruses</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">lytic gene expression</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Burkitt lymphoma cells</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">clozapine</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">antipsychotic drug</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">antiviral drug</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">enteroviruses</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">coxsackievirus B4</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">persistent infection</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">fluoxetine</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">resistance</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mutations</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">herpes B virus</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">macacine herpesvirus-1</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">genistein</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">flavonoids</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">acyclovir</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ganciclovir</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Plantago asiatica</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Clerodendrum trichotomum</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">RSV</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">therapeutic effects</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">acteoside</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">human antimicrobial peptides</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">antiviral strategies</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">defensins</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cathelicidins</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">hepcidins</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">transferrins</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">influenza A virus</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">brevilin A</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">antiviral</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">sesquiterpene lactone</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">replication</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">PRRSV</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">polyethylenimine</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">PEI</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">virion internalization</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">endocytosis</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">HIV</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">pediatrics</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Ethiopia</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">pre-treatment drug resistance</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">combination antiretroviral therapy (cART)</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">dried plasma spots</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">dried blood spots</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">sphingolipids</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">glycosphingolipids</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">viruses</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">lipid biosynthesis</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">flavivirus</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Japanese encephalitis virus</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">furin inhibitor</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">precursor membrane protein</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">measles virus</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">central nervous system</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">tropism</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">treatments</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">porcine reproductive and respiratory syndrome virus</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ginsenoside Rg1</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">antiviral activity</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">pro-inflammatory factor</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">NF-κB signaling pathway</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">acute/latent infection</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">congenital infection</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">antiviral agent</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">therapeutic strategies</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">nucleic acid-based therapeutic approach</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">HCMV vaccine</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">adoptive cell therapy</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Rev response element</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">chemical footprinting</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">SHAPE</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">drug discovery</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">branched peptides</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">herpesvirus</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">immediate-early</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">IE1</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">IE2</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ribozyme</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">RNA interference</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">CRISPR/Cas</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">small molecule</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">orthohantavirus</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">phenyl-benzotriazoles</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">C-FRA</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Porcine circovirus type 2</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">epigallocatechin gallate</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">heparan sulfate</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">antiviral effect</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">virus attachment</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">microvirin</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">lectin</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">human immunodeficiency virus</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">hepatitis C virus</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">antiviral inhibitor</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">non-immunogenic</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">viral entry</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">protein drugs</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">LUMS1</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">oleanane-type derivatives</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">influenza A virus (IAV)</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">virus entry inhibitors</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">hemagglutinin (HA)</subfield></datafield><datafield tag="776" ind1=" " ind2=" "><subfield code="z">3-03928-953-5</subfield></datafield><datafield tag="776" ind1=" " ind2=" "><subfield code="z">3-03928-954-3</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Adamson, Catherine</subfield><subfield code="4">oth</subfield></datafield><datafield tag="906" ind1=" " ind2=" "><subfield code="a">BOOK</subfield></datafield><datafield tag="ADM" ind1=" " ind2=" "><subfield code="b">2024-01-26 02:20:51 Europe/Vienna</subfield><subfield code="f">system</subfield><subfield code="c">marc21</subfield><subfield code="a">2022-04-04 09:22:53 Europe/Vienna</subfield><subfield code="g">false</subfield></datafield><datafield tag="AVE" ind1=" " ind2=" "><subfield code="i">DOAB Directory of Open Access Books</subfield><subfield code="P">DOAB Directory of Open Access Books</subfield><subfield code="x">https://eu02.alma.exlibrisgroup.com/view/uresolver/43ACC_OEAW/openurl?u.ignore_date_coverage=true&amp;portfolio_pid=5337899210004498&amp;Force_direct=true</subfield><subfield code="Z">5337899210004498</subfield><subfield code="b">Available</subfield><subfield code="8">5337899210004498</subfield></datafield></record></collection>

Similar Items