Mitochondrial Transport Proteins
Mitochondrial transporters are membrane-inserted proteins which provide a link between metabolic reactions occurring within the mitochondrial matrix and outside the organelles by catalyzing the translocation of numerous solutes across the mitochondrial membrane. They include the mitochondrial carrie...
Saved in:
| Sonstige: | |
|---|---|
| Year of Publication: | 2022 |
| Language: | English |
| Physical Description: | 1 electronic resource (476 p.) |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| id |
993545175604498 |
|---|---|
| ctrlnum |
(CKB)5680000000037727 (oapen)https://directory.doabooks.org/handle/20.500.12854/80949 (EXLCZ)995680000000037727 |
| collection |
bib_alma |
| record_format |
marc |
| spelling |
Palmieri, Ferdinando edt Mitochondrial Transport Proteins Basel MDPI - Multidisciplinary Digital Publishing Institute 2022 1 electronic resource (476 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier Mitochondrial transporters are membrane-inserted proteins which provide a link between metabolic reactions occurring within the mitochondrial matrix and outside the organelles by catalyzing the translocation of numerous solutes across the mitochondrial membrane. They include the mitochondrial carrier family members, the proteins involved in pyruvate transport, ABC transporters and channels, and are, therefore, essential for many biological processes and cell homeostasis. Identification and functional studies of many mitochondrial transporters have been performed over the years using both in vitro and in vivo systems. The few recently solved structures of these transporters have paved the way for further investigations. Furthermore, alterations in their function are responsible for several diseases. English Research & information: general bicssc Biology, life sciences bicssc hypoxia resistance to hypoxia mitochondria mitochondrial calcium transport mitochondrial calcium uniporter complex mitochondrial Ca2+-induced permeability transition pore cyclophilin D ATP synthase disease error of metabolism mitochondrial carrier mitochondrial carrier disease mitochondrial disease mitochondrial transporter membrane transport mutation SLC25. mitochondrial permeability transition apoptosis necrosis ischemia/reperfusion cancer neurodegeneration cyclosporin A metabolite transport mitochondrial pyruvate carrier sideroflexin TOM TIM chaperones TIM22 protein translocation mitochondrial biogenesis amino acid biological function ion inner mitochondrial membrane mitochondrial carrier family organic acid substrate specificity transport mechanism vitamin USMG5/DAPIT glucose-stimulated insulin secretion glucose-induced expression membrane subunits of ATP synthase ATP synthase oligomers mitochondrial cristae morphology metabolism metabolic disorders adult-onset type II citrullinemia (CTLN2) aspartate/glutamate carrier (AGC) animal model argininosuccinate synthetase (ASS) aversion to carbohydrates citrin food taste neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD) protein–protein interaction MPC lifespan pyruvate metabolism mitochondrial transport peroxisomes carrier cofactor ABC transporter aquaporin ion channels potassium channels ATP calcium ROS potassium channel openers MCF function plant metabolism plant development diseases VDAC1 virus pancreatic islets β-cell diabetes glucotoxicity glucolipotoxicity lipotoxicity mitochondrial carriers SLC transporters SLC25 SLC54 SLC55 LETM SLC56 sequence analysis protein targeting Voltage-Dependent Anion selective Channel isoforms oxidative post-translational modification gene promoter yeast bioenergetics SLC25A1 CIC CTP citrate inflammation 22.q11.2 NAFLD/NASH carnitine carnitine acyl-carnitine carrier carnitine acyl-carnitine translocase post-translational modification solute carrier family 25 SLC25A20 MCU mitochondrial Ca2+ uniporter Ca2+ signaling mitochondrial metabolism skeletal muscle mitochondria SLC25A51 NAD+ transporters NAD electrophysiology ATP-dependent potassium channel 3-0365-3410-5 3-0365-3409-1 Palmieri, Ferdinando oth |
| language |
English |
| format |
eBook |
| author2 |
Palmieri, Ferdinando |
| author_facet |
Palmieri, Ferdinando |
| author2_variant |
f p fp |
| author2_role |
Sonstige |
| title |
Mitochondrial Transport Proteins |
| spellingShingle |
Mitochondrial Transport Proteins |
| title_full |
Mitochondrial Transport Proteins |
| title_fullStr |
Mitochondrial Transport Proteins |
| title_full_unstemmed |
Mitochondrial Transport Proteins |
| title_auth |
Mitochondrial Transport Proteins |
| title_new |
Mitochondrial Transport Proteins |
| title_sort |
mitochondrial transport proteins |
| publisher |
MDPI - Multidisciplinary Digital Publishing Institute |
| publishDate |
2022 |
| physical |
1 electronic resource (476 p.) |
| isbn |
3-0365-3410-5 3-0365-3409-1 |
| illustrated |
Not Illustrated |
| work_keys_str_mv |
AT palmieriferdinando mitochondrialtransportproteins |
| status_str |
n |
| ids_txt_mv |
(CKB)5680000000037727 (oapen)https://directory.doabooks.org/handle/20.500.12854/80949 (EXLCZ)995680000000037727 |
| carrierType_str_mv |
cr |
| is_hierarchy_title |
Mitochondrial Transport Proteins |
| author2_original_writing_str_mv |
noLinkedField |
| _version_ |
1796649061232672768 |
| fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>05924nam-a2201777z--4500</leader><controlfield tag="001">993545175604498</controlfield><controlfield tag="005">20231214133342.0</controlfield><controlfield tag="006">m o d </controlfield><controlfield tag="007">cr|mn|---annan</controlfield><controlfield tag="008">202205s2022 xx |||||o ||| 0|eng d</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(CKB)5680000000037727</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(oapen)https://directory.doabooks.org/handle/20.500.12854/80949</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(EXLCZ)995680000000037727</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Palmieri, Ferdinando</subfield><subfield code="4">edt</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Mitochondrial Transport Proteins</subfield></datafield><datafield tag="260" ind1=" " ind2=" "><subfield code="a">Basel</subfield><subfield code="b">MDPI - Multidisciplinary Digital Publishing Institute</subfield><subfield code="c">2022</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 electronic resource (476 p.)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">computer</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">online resource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Mitochondrial transporters are membrane-inserted proteins which provide a link between metabolic reactions occurring within the mitochondrial matrix and outside the organelles by catalyzing the translocation of numerous solutes across the mitochondrial membrane. They include the mitochondrial carrier family members, the proteins involved in pyruvate transport, ABC transporters and channels, and are, therefore, essential for many biological processes and cell homeostasis. Identification and functional studies of many mitochondrial transporters have been performed over the years using both in vitro and in vivo systems. The few recently solved structures of these transporters have paved the way for further investigations. Furthermore, alterations in their function are responsible for several diseases.</subfield></datafield><datafield tag="546" ind1=" " ind2=" "><subfield code="a">English</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Research & information: general</subfield><subfield code="2">bicssc</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Biology, life sciences</subfield><subfield code="2">bicssc</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">hypoxia</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">resistance to hypoxia</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mitochondria</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mitochondrial calcium transport</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mitochondrial calcium uniporter complex</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mitochondrial Ca2+-induced permeability transition pore</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cyclophilin D</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ATP synthase</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">disease</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">error of metabolism</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mitochondrial carrier</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mitochondrial carrier disease</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mitochondrial disease</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mitochondrial transporter</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">membrane transport</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mutation</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">SLC25.</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mitochondrial permeability transition</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">apoptosis</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">necrosis</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ischemia/reperfusion</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cancer</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">neurodegeneration</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cyclosporin A</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">metabolite transport</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mitochondrial pyruvate carrier</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">sideroflexin</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">TOM</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">TIM chaperones</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">TIM22</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">protein translocation</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mitochondrial biogenesis</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">amino acid</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">biological function</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ion</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">inner mitochondrial membrane</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mitochondrial carrier family</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">organic acid</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">substrate specificity</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">transport mechanism</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">vitamin</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">USMG5/DAPIT</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">glucose-stimulated insulin secretion</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">glucose-induced expression</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">membrane subunits of ATP synthase</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ATP synthase oligomers mitochondrial cristae morphology</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">metabolism</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">metabolic disorders</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">adult-onset type II citrullinemia (CTLN2)</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">aspartate/glutamate carrier (AGC)</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">animal model</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">argininosuccinate synthetase (ASS)</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">aversion to carbohydrates</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">citrin</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">food taste</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD)</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">protein–protein interaction</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">MPC</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">lifespan</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">pyruvate metabolism</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mitochondrial transport</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">peroxisomes</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">carrier</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cofactor</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ABC transporter</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">aquaporin</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ion channels</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">potassium channels</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ATP</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">calcium</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ROS</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">potassium channel openers</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">MCF</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">function</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">plant metabolism</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">plant development</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">diseases</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">VDAC1</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">virus</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">pancreatic islets</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">β-cell</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">diabetes</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">glucotoxicity</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">glucolipotoxicity</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">lipotoxicity</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mitochondrial carriers</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">SLC transporters</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">SLC25</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">SLC54</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">SLC55</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">LETM</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">SLC56</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">sequence analysis</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">protein targeting</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Voltage-Dependent Anion selective Channel</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">isoforms</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">oxidative post-translational modification</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">gene promoter</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">yeast</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">bioenergetics</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">SLC25A1</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">CIC</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">CTP</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">citrate</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">inflammation</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">22.q11.2</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">NAFLD/NASH</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">carnitine</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">carnitine acyl-carnitine carrier</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">carnitine acyl-carnitine translocase</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">post-translational modification</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">solute carrier family 25</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">SLC25A20</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">MCU</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mitochondrial Ca2+ uniporter</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Ca2+ signaling</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mitochondrial metabolism</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">skeletal muscle mitochondria</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">SLC25A51</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">NAD+ transporters</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">NAD</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">electrophysiology</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ATP-dependent potassium channel</subfield></datafield><datafield tag="776" ind1=" " ind2=" "><subfield code="z">3-0365-3410-5</subfield></datafield><datafield tag="776" ind1=" " ind2=" "><subfield code="z">3-0365-3409-1</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Palmieri, Ferdinando</subfield><subfield code="4">oth</subfield></datafield><datafield tag="906" ind1=" " ind2=" "><subfield code="a">BOOK</subfield></datafield><datafield tag="ADM" ind1=" " ind2=" "><subfield code="b">2023-12-15 05:51:08 Europe/Vienna</subfield><subfield code="f">system</subfield><subfield code="c">marc21</subfield><subfield code="a">2022-05-14 21:41:54 Europe/Vienna</subfield><subfield code="g">false</subfield></datafield><datafield tag="AVE" ind1=" " ind2=" "><subfield code="i">DOAB Directory of Open Access Books</subfield><subfield code="P">DOAB Directory of Open Access Books</subfield><subfield code="x">https://eu02.alma.exlibrisgroup.com/view/uresolver/43ACC_OEAW/openurl?u.ignore_date_coverage=true&portfolio_pid=5337875110004498&Force_direct=true</subfield><subfield code="Z">5337875110004498</subfield><subfield code="b">Available</subfield><subfield code="8">5337875110004498</subfield></datafield></record></collection> |