The Search for Biological Active Agent(s) From Actinobacteria, 2nd Edition
There is a large market demand for new drugs. The existing chronic or common ailments without cures, development of new diseases with unknown causes, and the widespread existence of antibiotic-resistant pathogens, have driven this field of research further by looking at all potential sources of natu...
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Lee, Learn-Han edt The Search for Biological Active Agent(s) From Actinobacteria, 2nd Edition Search for Biological Active Agent Frontiers Media SA 2020 1 electronic resource (312 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier There is a large market demand for new drugs. The existing chronic or common ailments without cures, development of new diseases with unknown causes, and the widespread existence of antibiotic-resistant pathogens, have driven this field of research further by looking at all potential sources of natural products. To date, microbes have made a significant contribution to the health and well-being of people globally. The discoveries of useful metabolites produced by microbes have resulted in a significant proportion of pharmaceutical products in today’s market. Therefore, the investigation and identification of bioactive compound(s) producing microbes is always of great interest to researchers. Actinobacteria are one of the most important and efficient groups of natural metabolite producers. Among the numerous genera, Streptomyces have been recognized as prolific producers of useful natural compounds, as they provide more than half of the naturally-occurring antibiotics isolated to-date and continue to emerge as the primary source of new bioactive compounds. Certainly, these potentials have attracted ample research interest and a wide range of biological activities have been subsequently screened by researchers with the utilization of different In vitro and In vivo model of experiments. Literature evidence has shown that a significant number of interesting compounds produced by Actinobacteria were exhibiting either strong anticancer or neuroprotective activity. The further in depth studies have then established the modulation of apoptotic pathway was involved in those observed bioactivities. These findings indirectly prove the biopharmaceutical potential possessed by Actinobacteria and at the same time substantiate the importance of diverse pharmaceutical evaluations on Actinobacteria. In fact, many novel compounds discovered from Actinobacteria with strong potential in clinical applications have been developed into new drugs by pharmaceutical companies. Together with the advancement in science and technology, it is predicted that there would be an expedition in discoveries of new bioactive compounds producing Actinobacteria from various sources, including soil and marine sources. In light of these current needs, and great interest in the scope of this research, this book seeks to contribute on the investigation of different biological active compound(s) producing actinobacteria which are exhibiting antimicrobial, antioxidant, neuroprotective, anticancer activities and similar. English Science: general issues bicssc Medical microbiology & virology bicssc Microbiology (non-medical) bicssc actinobacteria drug discovery Streptomyces bioactive next generation marine terrestrial 2-88963-639-9 Chan, Kok-Gan edt Stach, Jem edt Wellington, Elizabeth M. H. edt Goh, Bey-Hing edt Lee, Learn-Han oth Chan, Kok-Gan oth Stach, Jem oth Wellington, Elizabeth M. H. oth Goh, Bey-Hing oth |
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English |
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author2 |
Chan, Kok-Gan Stach, Jem Wellington, Elizabeth M. H. Goh, Bey-Hing Lee, Learn-Han Chan, Kok-Gan Stach, Jem Wellington, Elizabeth M. H. Goh, Bey-Hing |
author_facet |
Chan, Kok-Gan Stach, Jem Wellington, Elizabeth M. H. Goh, Bey-Hing Lee, Learn-Han Chan, Kok-Gan Stach, Jem Wellington, Elizabeth M. H. Goh, Bey-Hing |
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l h l lhl k g c kgc j s js e m h w emh emhw b h g bhg |
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HerausgeberIn HerausgeberIn HerausgeberIn HerausgeberIn Sonstige Sonstige Sonstige Sonstige Sonstige |
title |
The Search for Biological Active Agent(s) From Actinobacteria, 2nd Edition |
spellingShingle |
The Search for Biological Active Agent(s) From Actinobacteria, 2nd Edition |
title_full |
The Search for Biological Active Agent(s) From Actinobacteria, 2nd Edition |
title_fullStr |
The Search for Biological Active Agent(s) From Actinobacteria, 2nd Edition |
title_full_unstemmed |
The Search for Biological Active Agent(s) From Actinobacteria, 2nd Edition |
title_auth |
The Search for Biological Active Agent(s) From Actinobacteria, 2nd Edition |
title_alt |
Search for Biological Active Agent |
title_new |
The Search for Biological Active Agent(s) From Actinobacteria, 2nd Edition |
title_sort |
the search for biological active agent(s) from actinobacteria, 2nd edition |
publisher |
Frontiers Media SA |
publishDate |
2020 |
physical |
1 electronic resource (312 p.) |
isbn |
2-88963-639-9 |
illustrated |
Not Illustrated |
work_keys_str_mv |
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(CKB)5400000000041414 (oapen)https://directory.doabooks.org/handle/20.500.12854/73781 (EXLCZ)995400000000041414 |
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The Search for Biological Active Agent(s) From Actinobacteria, 2nd Edition |
author2_original_writing_str_mv |
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Among the numerous genera, Streptomyces have been recognized as prolific producers of useful natural compounds, as they provide more than half of the naturally-occurring antibiotics isolated to-date and continue to emerge as the primary source of new bioactive compounds. Certainly, these potentials have attracted ample research interest and a wide range of biological activities have been subsequently screened by researchers with the utilization of different In vitro and In vivo model of experiments. Literature evidence has shown that a significant number of interesting compounds produced by Actinobacteria were exhibiting either strong anticancer or neuroprotective activity. The further in depth studies have then established the modulation of apoptotic pathway was involved in those observed bioactivities. 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