Redox-Active Molecules as Therapeutic Agents
Oxidative stress and altered redox signaling have been described in a plethora of pathological conditions. Redox-active molecules can thus potentially be used to modulate the etiology/progression of such diseases. Recent advances in molecular biology and pharmacology have strengthened this area of r...
Saved in:
Sonstige: | |
---|---|
Year of Publication: | 2022 |
Language: | English |
Physical Description: | 1 electronic resource (266 p.) |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
993545039704498 |
---|---|
ctrlnum |
(CKB)5690000000011954 (oapen)https://directory.doabooks.org/handle/20.500.12854/87539 (EXLCZ)995690000000011954 |
collection |
bib_alma |
record_format |
marc |
spelling |
Fernandes, Ana Sofia edt Redox-Active Molecules as Therapeutic Agents Basel MDPI - Multidisciplinary Digital Publishing Institute 2022 1 electronic resource (266 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier Oxidative stress and altered redox signaling have been described in a plethora of pathological conditions. Redox-active molecules can thus potentially be used to modulate the etiology/progression of such diseases. Recent advances in molecular biology and pharmacology have strengthened this area of research by providing novel mechanistic insights. This book compiles a collection of 13 articles, covering a range of topics from in vitro studies to clinical research, focused on the potential therapeutic effects of either natural or synthetic compounds, applicable to different redox-related diseases. English Research & information: general bicssc Biology, life sciences bicssc non-small cell lung cancer cisplatin apurinic/apyrimidinic endonuclease 1 E3330 cytotoxicity apoptosis migration invasion oxidative stress sildenafil DNA damage systemic sclerosis bioactivity-based assays cyanidin metabolomics Rubus genus (poly)phenols yeast-based discovery platform withanolide breast cancer mitochondrial reactive oxygen species peroxiredoxin 3 pro-oxidant therapy thiostrepton GSH Cysteamine N-acetyl cysteine KEAP1 NRF2 ATF4 adipose-derived mesenchymal stem cell amniotic membrane-derived mesenchymal stem cell antioxidants assisted reproductive technology conditioned medium embryo in vitro culture in vitro fertilization BAPN cell invasion EMT lysyl-oxidase lysyl-oxidase like 2 metastases inhibitors doxorubicin chemoresistance redox signaling nuclear factor erythroid 2-related factor 2 (Nrf2) cancer therapy hydrogen sulfide reactive oxygen species H2S donors cardiorenal syndrome thiosulfate selenium-enriched Enterococcus faecium selenium-enriched Streptococcus thermophilus antioxidant capacity glutathione reductase glutathione peroxidase CD IGS rats lactic acid bacteria verbascoside hypercholesterolemia prostate cancer curcumin carnosic acid cell cycle OxPhos SGK1 3-0365-4381-3 3-0365-4382-1 Fernandes, Ana Sofia oth |
language |
English |
format |
eBook |
author2 |
Fernandes, Ana Sofia |
author_facet |
Fernandes, Ana Sofia |
author2_variant |
a s f as asf |
author2_role |
Sonstige |
title |
Redox-Active Molecules as Therapeutic Agents |
spellingShingle |
Redox-Active Molecules as Therapeutic Agents |
title_full |
Redox-Active Molecules as Therapeutic Agents |
title_fullStr |
Redox-Active Molecules as Therapeutic Agents |
title_full_unstemmed |
Redox-Active Molecules as Therapeutic Agents |
title_auth |
Redox-Active Molecules as Therapeutic Agents |
title_new |
Redox-Active Molecules as Therapeutic Agents |
title_sort |
redox-active molecules as therapeutic agents |
publisher |
MDPI - Multidisciplinary Digital Publishing Institute |
publishDate |
2022 |
physical |
1 electronic resource (266 p.) |
isbn |
3-0365-4381-3 3-0365-4382-1 |
illustrated |
Not Illustrated |
work_keys_str_mv |
AT fernandesanasofia redoxactivemoleculesastherapeuticagents |
status_str |
n |
ids_txt_mv |
(CKB)5690000000011954 (oapen)https://directory.doabooks.org/handle/20.500.12854/87539 (EXLCZ)995690000000011954 |
carrierType_str_mv |
cr |
is_hierarchy_title |
Redox-Active Molecules as Therapeutic Agents |
author2_original_writing_str_mv |
noLinkedField |
_version_ |
1787548485160009728 |
fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>03879nam-a2201141z--4500</leader><controlfield tag="001">993545039704498</controlfield><controlfield tag="005">20231214133507.0</controlfield><controlfield tag="006">m o d </controlfield><controlfield tag="007">cr|mn|---annan</controlfield><controlfield tag="008">202207s2022 xx |||||o ||| 0|eng d</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(CKB)5690000000011954</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(oapen)https://directory.doabooks.org/handle/20.500.12854/87539</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(EXLCZ)995690000000011954</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Fernandes, Ana Sofia</subfield><subfield code="4">edt</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Redox-Active Molecules as Therapeutic Agents</subfield></datafield><datafield tag="260" ind1=" " ind2=" "><subfield code="a">Basel</subfield><subfield code="b">MDPI - Multidisciplinary Digital Publishing Institute</subfield><subfield code="c">2022</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 electronic resource (266 p.)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">computer</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">online resource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Oxidative stress and altered redox signaling have been described in a plethora of pathological conditions. Redox-active molecules can thus potentially be used to modulate the etiology/progression of such diseases. Recent advances in molecular biology and pharmacology have strengthened this area of research by providing novel mechanistic insights. This book compiles a collection of 13 articles, covering a range of topics from in vitro studies to clinical research, focused on the potential therapeutic effects of either natural or synthetic compounds, applicable to different redox-related diseases.</subfield></datafield><datafield tag="546" ind1=" " ind2=" "><subfield code="a">English</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Research & information: general</subfield><subfield code="2">bicssc</subfield></datafield><datafield tag="650" ind1=" " ind2="7"><subfield code="a">Biology, life sciences</subfield><subfield code="2">bicssc</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">non-small cell lung cancer</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cisplatin</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">apurinic/apyrimidinic endonuclease 1</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">E3330</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cytotoxicity</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">apoptosis</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">migration</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">invasion</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">oxidative stress</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">sildenafil</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">DNA damage</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">systemic sclerosis</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">bioactivity-based assays</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cyanidin</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">metabolomics</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Rubus genus</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">(poly)phenols</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">yeast-based discovery platform</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">withanolide</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">breast cancer</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">mitochondrial reactive oxygen species</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">peroxiredoxin 3</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">pro-oxidant therapy</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">thiostrepton</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">GSH</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Cysteamine</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">N-acetyl cysteine</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">KEAP1</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">NRF2</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">ATF4</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">adipose-derived mesenchymal stem cell</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">amniotic membrane-derived mesenchymal stem cell</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">antioxidants</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">assisted reproductive technology</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">conditioned medium</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">embryo</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">in vitro culture</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">in vitro fertilization</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">BAPN</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cell invasion</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">EMT</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">lysyl-oxidase</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">lysyl-oxidase like 2</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">metastases</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">inhibitors</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">doxorubicin</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">chemoresistance</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">redox signaling</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">nuclear factor erythroid 2-related factor 2 (Nrf2)</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cancer therapy</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">hydrogen sulfide</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">reactive oxygen species</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">H2S donors</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cardiorenal syndrome</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">thiosulfate</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">selenium-enriched Enterococcus faecium</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">selenium-enriched Streptococcus thermophilus</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">antioxidant capacity</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">glutathione reductase</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">glutathione peroxidase</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">CD IGS rats</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">lactic acid bacteria</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">verbascoside</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">hypercholesterolemia</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">prostate cancer</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">curcumin</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">carnosic acid</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">cell cycle</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">OxPhos</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">SGK1</subfield></datafield><datafield tag="776" ind1=" " ind2=" "><subfield code="z">3-0365-4381-3</subfield></datafield><datafield tag="776" ind1=" " ind2=" "><subfield code="z">3-0365-4382-1</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Fernandes, Ana Sofia</subfield><subfield code="4">oth</subfield></datafield><datafield tag="906" ind1=" " ind2=" "><subfield code="a">BOOK</subfield></datafield><datafield tag="ADM" ind1=" " ind2=" "><subfield code="b">2023-12-15 05:55:49 Europe/Vienna</subfield><subfield code="f">system</subfield><subfield code="c">marc21</subfield><subfield code="a">2022-07-14 08:50:39 Europe/Vienna</subfield><subfield code="g">false</subfield></datafield><datafield tag="AVE" ind1=" " ind2=" "><subfield code="i">DOAB Directory of Open Access Books</subfield><subfield code="P">DOAB Directory of Open Access Books</subfield><subfield code="x">https://eu02.alma.exlibrisgroup.com/view/uresolver/43ACC_OEAW/openurl?u.ignore_date_coverage=true&portfolio_pid=5337834470004498&Force_direct=true</subfield><subfield code="Z">5337834470004498</subfield><subfield code="b">Available</subfield><subfield code="8">5337834470004498</subfield></datafield></record></collection> |