Why Have Cortical Layers? What Is the Function of Layering? Do Neurons in Cortex Integrate Information Across Different Layers?
This research topic was suggested by Robert Sachdev to bring together a series of articles dealing with the laminar organization of the neocortex. By convention, there are six cortical layers but this number may vary throughout the cerebral cortex of a given species or between species: many regions...
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Superior document: | Frontiers Research Topics |
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Year of Publication: | 2018 |
Language: | English |
Series: | Frontiers Research Topics
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Physical Description: | 1 electronic resource (208 p.) |
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Javier DeFelipe auth Why Have Cortical Layers? What Is the Function of Layering? Do Neurons in Cortex Integrate Information Across Different Layers? Frontiers Media SA 2018 1 electronic resource (208 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier Frontiers Research Topics This research topic was suggested by Robert Sachdev to bring together a series of articles dealing with the laminar organization of the neocortex. By convention, there are six cortical layers but this number may vary throughout the cerebral cortex of a given species or between species: many regions lack one or more layers, whereas in other regions there are more than six layers. The laminar location of cortical neurons —their cell bodies— is determined during development. However, neurons are more than their cell bodies; they also have dendrites that may span within a given layer (intralaminar neurons) or across a variety of layers (translaminar neurons). For example, layer V pyramidal neurons have dendrites that span the entire cortical depth, whereas layer III pyramidal neurons have dendrites that span across layers I to IV. Some GABAergic interneurons have dendrites located within a cortical layer (e.g., neurogliaform cells), whereas the dendrites of other interneurons span several layers (e.g., bitufted cells). For neurons having dendrites that cross laminar boundaries, one might ask, why segregate their cell bodies so carefully into lamina? Among many other obvious questions: What is the evidence for or against integration of information across laminae for neurons whose dendrites span several layers? A traditional view is that activity flows through cortical layers in a feed-forward manner, going from layer IV, to layers II and III and onwards. Another view is that cortical layers can have distinct inputs that activate them, triggering spikes. Can processing sequences be state dependent? Furthermore, different cortical layers have distinct transcriptomic profiles, neurochemical attributes, connectivity patterns, number and types of synapses and many other structural attributes. Thus, based on anatomy, or physiology or imaging: What is the function of each cortical layer? What do the different layers do? English periallocortex receptors cell types GABAergic connectivity isocortex insular cortex olfactory Reeler Pyramidal neurons Cortical evolution 2-88945-660-9 Kathleen Rockland auth |
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English |
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Javier DeFelipe |
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Javier DeFelipe Why Have Cortical Layers? What Is the Function of Layering? Do Neurons in Cortex Integrate Information Across Different Layers? Frontiers Research Topics |
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Javier DeFelipe Kathleen Rockland |
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Kathleen Rockland |
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Javier DeFelipe |
title |
Why Have Cortical Layers? What Is the Function of Layering? Do Neurons in Cortex Integrate Information Across Different Layers? |
title_full |
Why Have Cortical Layers? What Is the Function of Layering? Do Neurons in Cortex Integrate Information Across Different Layers? |
title_fullStr |
Why Have Cortical Layers? What Is the Function of Layering? Do Neurons in Cortex Integrate Information Across Different Layers? |
title_full_unstemmed |
Why Have Cortical Layers? What Is the Function of Layering? Do Neurons in Cortex Integrate Information Across Different Layers? |
title_auth |
Why Have Cortical Layers? What Is the Function of Layering? Do Neurons in Cortex Integrate Information Across Different Layers? |
title_new |
Why Have Cortical Layers? What Is the Function of Layering? Do Neurons in Cortex Integrate Information Across Different Layers? |
title_sort |
why have cortical layers? what is the function of layering? do neurons in cortex integrate information across different layers? |
series |
Frontiers Research Topics |
series2 |
Frontiers Research Topics |
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Frontiers Media SA |
publishDate |
2018 |
physical |
1 electronic resource (208 p.) |
isbn |
2-88945-660-9 |
illustrated |
Not Illustrated |
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Frontiers Research Topics |
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Why Have Cortical Layers? What Is the Function of Layering? Do Neurons in Cortex Integrate Information Across Different Layers? |
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Frontiers Research Topics |
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