Animal experimentation : : working towards a paradigm change / / edited by Kathrin Herrmann, Kimberley Jayne.

• TeilnehmendeR: Herrmann, Kathrin,
• Place / Publishing House: Leiden ;, Boston : : Brill,, 2019.
• Year of Publication: 2019
• Edition: 1st ed.
• Language: English
• Series: Human-Animal Studies 22.
• Physical Description: 1 online resource.

Animal experimentation has been one of the most controversial areas of animal use, mainly due to the intentional harms inflicted upon animals for the sake of hoped-for benefits in humans. Despite this rationale for continued animal experimentation, shortcomings of this practice have become increasingly more apparent and well-documented. However, these limitations are not yet widely known or appreciated, and there is a danger that they may simply be ignored. The 51 experts who have contributed to Animal Experimentation: Working Towards a Paradigm Change critically review current animal use in science, present new and innovative non-animal approaches to address urgent scientific questions, and offer a roadmap towards an animal-free world of science.

Table of Contents

Front Matter -- Copyright Page -- Dedication -- Foreword -- Preface -- Acknowledgements -- Contributors -- Introduction -- Why and How to Shift the Paradigm -- Refinement on the Way Towards Replacement: Are We Doing What We Can? / Kathrin Herrmann -- How to Evaluate the Science of Non-human Animal Use in Biomedical Research and Testing: A Proposed Format for Debate / Ray Greek and Lisa A. Kramer -- How Can the Final Goal of Completely Replacing Animal Procedures Successfully Be Achieved? / Christiane Baumgartl-Simons and Christiane Hohensee -- Disease Prevention with a Plant-based Lifestyle / Sabina V. Vyas -- Politics and Legislation of Animal Experimentation -- Political Campaigning: Where Scientific and Ethical Arguments Meet Public Policy / Emily McIvor -- Rethinking the 3Rs: From Whitewashing to Rights / Charlotte E. Blattner -- Contesting Animal Experiments through Ethics and Epistemology: In Defense of a Political Critique of Animal Experimentation / Arianna Ferrari -- Openness in Animal Experimentation -- The Moral Status of Animal Research Subjects in Industry: A Stakeholder Analysis / Sarah Kenehan -- Increasing the Transparency of Animal Experimentation: An Australian Perspective / Monika Merkes and Rob Buttrose -- Wasted Money in United States Biomedical and Agricultural Animal Research / Jim Keen -- The Ethics and Philosophy of Animal Experimentation -- Ethics, Efficacy, and Decision-making in Animal Research / Lawrence A. Hansen and Kori Ann Kosberg -- Beyond Plausibility Checks: A Case for Moral Doubt in Review Processes of Animal Experimentation / Mara-Daria Cojocaru and Philipp von Gall -- Human Wrongs in Animal Research: A Focus on Moral Injury and Reification / Jane Johnson and Anna Smajdor -- Effectiveness of the Animal Model -- Critically Evaluating Animal Research / Andrew Knight -- Extrapolation of Animal Research Data to Humans: An Analysis of the Evidence / Rebecca Ram -- Is Animal-based Biomedical Research Being Used in Its Original Context? / Constança Carvalho , Daniel Alves , Andrew Knight and Luis Vicente -- The Scientific Problems with Using Non-Human Animals to Predict Human Response to Drugs and Disease / Ray Greek and Lisa A. Kramer -- Replacing Animal Tests to Improve Safety for Humans / Kathy Archibald , Robert Coleman and Tamara Drake -- Genetic Modification of Animals: Scientific and Ethical Issues / Jarrod Bailey -- Animal Research for Alzheimer Disease: Failures of Science and Ethics / John J. Pippin , Sarah E. Cavanaugh and Francesca Pistollato -- Behavioral Research on Captive Animals: Scientific and Ethical Concerns / Kimberley Jayne and Adam See -- Animal-free Education and Training -- Modernizing Biomedical Training: Replacing Live Animal Laboratories with Human Simulation / John Pawlowski , David Feinstein , Marie L. Crandall and Shalin Gala -- Humane Education: The Tool for Scientific Revolution in Brazil / Vanessa Carli Bones , Rita de Cássia Maria Garcia , Gutemberg Gomes Alves , Rita Leal Paixão , Alexandro Aluísio Rocha , Karynn Capilé and Róber Bachinski -- The Paradigm Shift: Advanced Animal-free Approaches -- Recent Developments in Alternatives to Animal Testing / Katy Taylor.