Drug metabolism, pharmacokinetics and bioanalysis / / special issue editors, Hye Suk Lee, Kwang-Hyeon Liu.
Drug metabolism/pharmacokinetics and drug interaction studies have been extensively carried out in order to secure the druggability and safety of new chemical entities throughout the development of new drugs. Recently, drug metabolism and transport by phase II drug metabolizing enzymes and drug tran...
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| Year of Publication: | 2019 |
| Language: | English |
| Physical Description: | 1 electronic resource (230 p.) |
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(CKB)4920000000095019 (oapen)https://directory.doabooks.org/handle/20.500.12854/45509 (EXLCZ)994920000000095019 |
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Drug metabolism, pharmacokinetics and bioanalysis / special issue editors, Hye Suk Lee, Kwang-Hyeon Liu. MDPI - Multidisciplinary Digital Publishing Institute 2019 1 electronic resource (230 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier Drug metabolism/pharmacokinetics and drug interaction studies have been extensively carried out in order to secure the druggability and safety of new chemical entities throughout the development of new drugs. Recently, drug metabolism and transport by phase II drug metabolizing enzymes and drug transporters, respectively, as well as phase I drug metabolizing enzymes, have been studied. A combination of biochemical advances in the function and regulation of drug metabolizing enzymes and automated analytical technologies are revolutionizing drug metabolism research. There are also potential drug–drug interactions with co-administered drugs due to inhibition and/or induction of drug metabolic enzymes and drug transporters. In addition, drug interaction studies have been actively performed to develop substrate cocktails that do not interfere with each other and a simultaneous analytical method of substrate drugs and their metabolites using a tandem mass spectrometer. This Special Issue has the aim of highlighting current progress in drug metabolism/pharmacokinetics, drug interactions, and bioanalysis. English Creative Commons NonCommercial-NoDerivs https://creativecommons.org/licenses/https://mdpi.com/books/pdfview/book/1904 Description based on online resource ; title from PDF title page (viewed on 03/24/2021) Unrestricted online access star human liver microsomes alcohol addiction UGT ultra-high-pressure liquid chromatography adalimumab procainamide LC-MS/MS DA-9805 paeonol LC-QTOF-MS/MS YRA-1909 chlorogenic acid immunoprecipitation Eurycoma longifolia CYP caffeic acid rat pharmaceutical excipient Korean red ginseng extract Stauntonia hexaphylla leaf extract bioanalysis HPLC-MS/MS B6 eurycomanone bioavailability drying technology GB3 diclofenac 129-Glatm1Kul/J aglycone caffeic acid O-glucuronides organic anion transporting polypeptide protein precipitation metabolic stability Fabry disease biopharmaceuticals imperatorin neochlorogenic acid gastric ulcer saikosaponin a hair anthraquinone acetyl tributyl citrate pharmacokinetics brain distribution mematine ethyl glucuronide pharmacokinetic loxoprofen liquid chromatography-quadrupole TOF MS glucuronidation esomeprazole metformin cytochrome P450 glycoside AUDIT score protein stability efficacy LC-HR/MS cryptochlorogenic acid aceclofenac drug interaction liquid chromatography-tandem mass spectrometry Osthenol plasma N-acetylprocainamide diabetes Drugs Metabolism. 3-03897-916-3 Lee, Hye Suk (Pharmacist), editor. Liu, Kwang-Hyeon, editor. |
| language |
English |
| format |
eBook |
| author2 |
Lee, Hye Suk (Pharmacist), Liu, Kwang-Hyeon, |
| author_facet |
Lee, Hye Suk (Pharmacist), Liu, Kwang-Hyeon, |
| author2_variant |
h s l hs hsl k h l khl |
| author2_role |
TeilnehmendeR TeilnehmendeR |
| title |
Drug metabolism, pharmacokinetics and bioanalysis / |
| spellingShingle |
Drug metabolism, pharmacokinetics and bioanalysis / |
| title_full |
Drug metabolism, pharmacokinetics and bioanalysis / special issue editors, Hye Suk Lee, Kwang-Hyeon Liu. |
| title_fullStr |
Drug metabolism, pharmacokinetics and bioanalysis / special issue editors, Hye Suk Lee, Kwang-Hyeon Liu. |
| title_full_unstemmed |
Drug metabolism, pharmacokinetics and bioanalysis / special issue editors, Hye Suk Lee, Kwang-Hyeon Liu. |
| title_auth |
Drug metabolism, pharmacokinetics and bioanalysis / |
| title_new |
Drug metabolism, pharmacokinetics and bioanalysis / |
| title_sort |
drug metabolism, pharmacokinetics and bioanalysis / |
| publisher |
MDPI - Multidisciplinary Digital Publishing Institute |
| publishDate |
2019 |
| physical |
1 electronic resource (230 p.) |
| isbn |
3-03897-917-1 3-03897-916-3 |
| callnumber-first |
R - Medicine |
| callnumber-subject |
RM - Therapeutics and Pharmacology |
| callnumber-label |
RM301 |
| callnumber-sort |
RM 3301.55 |
| illustrated |
Not Illustrated |
| dewey-hundreds |
600 - Technology |
| dewey-tens |
610 - Medicine & health |
| dewey-ones |
615 - Pharmacology & therapeutics |
| dewey-full |
615.1 |
| dewey-sort |
3615.1 |
| dewey-raw |
615.1 |
| dewey-search |
615.1 |
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AT leehyesuk drugmetabolismpharmacokineticsandbioanalysis AT liukwanghyeon drugmetabolismpharmacokineticsandbioanalysis |
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(CKB)4920000000095019 (oapen)https://directory.doabooks.org/handle/20.500.12854/45509 (EXLCZ)994920000000095019 |
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Drug metabolism, pharmacokinetics and bioanalysis / |
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