Inflammation in the CNS: Advancing the Field Using Intravital Imaging
Inflammation of the CNS can have devastating, long-lived, and in some cases fatal consequences for patients. The stimuli that can induce CNS inflammation are diverse, and include infectious agents, autoimmune responses against CNS-expressed antigens, and sterile inflammation following ischemia or tr...
Saved in:
Superior document: | Frontiers Research Topics |
---|---|
: | |
Year of Publication: | 2017 |
Language: | English |
Series: | Frontiers Research Topics
|
Physical Description: | 1 electronic resource (108 p.) |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
993543812904498 |
---|---|
ctrlnum |
(CKB)4100000002484702 (oapen)https://directory.doabooks.org/handle/20.500.12854/50187 (EXLCZ)994100000002484702 |
collection |
bib_alma |
record_format |
marc |
spelling |
Saparna Pai auth Inflammation in the CNS: Advancing the Field Using Intravital Imaging Inflammation in the CNS Frontiers Media SA 2017 1 electronic resource (108 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier Frontiers Research Topics Inflammation of the CNS can have devastating, long-lived, and in some cases fatal consequences for patients. The stimuli that can induce CNS inflammation are diverse, and include infectious agents, autoimmune responses against CNS-expressed antigens, and sterile inflammation following ischemia or traumatic injury. In these conditions, cells of the immune system play central roles in promulgation and resolution of the inflammatory response. However, the immunological mechanisms at work in these diverse responses differ according to the nature of the response. Our understanding of the actions of immune cells in the CNS has been restricted by the difficulty in visualising leukocytes as they undergo recruitment from the cerebral microvasculature and following their entry into the CNS parenchyma. However, advances in in vivo microscopy over the last 10-15 years have overcome many of these difficulties, and studies using these forms of microscopy have revealed a wealth of new information regarding the cellular and molecular mechanisms of CNS inflammation. This Research Topic brings together state of the art reviews examining the use of in vivo imaging in investigating inflammation and leukocyte behaviour in the CNS. Papers in this Research Topic describe how in vivo microscopy has increased our understanding of the actions of immune cells in the inflamed CNS, following various stimuli including autoimmunity, infection and sterile inflammation. English Intravital Imaging Brain Inflammation CNS disorders Leukocytes 2-88945-364-2 Wolfgang Weninger auth Michael J. Hickey auth |
language |
English |
format |
eBook |
author |
Saparna Pai |
spellingShingle |
Saparna Pai Inflammation in the CNS: Advancing the Field Using Intravital Imaging Frontiers Research Topics |
author_facet |
Saparna Pai Wolfgang Weninger Michael J. Hickey |
author_variant |
s p sp |
author2 |
Wolfgang Weninger Michael J. Hickey |
author2_variant |
w w ww m j h mjh |
author_sort |
Saparna Pai |
title |
Inflammation in the CNS: Advancing the Field Using Intravital Imaging |
title_full |
Inflammation in the CNS: Advancing the Field Using Intravital Imaging |
title_fullStr |
Inflammation in the CNS: Advancing the Field Using Intravital Imaging |
title_full_unstemmed |
Inflammation in the CNS: Advancing the Field Using Intravital Imaging |
title_auth |
Inflammation in the CNS: Advancing the Field Using Intravital Imaging |
title_alt |
Inflammation in the CNS |
title_new |
Inflammation in the CNS: Advancing the Field Using Intravital Imaging |
title_sort |
inflammation in the cns: advancing the field using intravital imaging |
series |
Frontiers Research Topics |
series2 |
Frontiers Research Topics |
publisher |
Frontiers Media SA |
publishDate |
2017 |
physical |
1 electronic resource (108 p.) |
isbn |
2-88945-364-2 |
illustrated |
Not Illustrated |
work_keys_str_mv |
AT saparnapai inflammationinthecnsadvancingthefieldusingintravitalimaging AT wolfgangweninger inflammationinthecnsadvancingthefieldusingintravitalimaging AT michaeljhickey inflammationinthecnsadvancingthefieldusingintravitalimaging AT saparnapai inflammationinthecns AT wolfgangweninger inflammationinthecns AT michaeljhickey inflammationinthecns |
status_str |
n |
ids_txt_mv |
(CKB)4100000002484702 (oapen)https://directory.doabooks.org/handle/20.500.12854/50187 (EXLCZ)994100000002484702 |
carrierType_str_mv |
cr |
hierarchy_parent_title |
Frontiers Research Topics |
is_hierarchy_title |
Inflammation in the CNS: Advancing the Field Using Intravital Imaging |
container_title |
Frontiers Research Topics |
author2_original_writing_str_mv |
noLinkedField noLinkedField |
_version_ |
1796649061834555392 |
fullrecord |
<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>02525nam-a2200361z--4500</leader><controlfield tag="001">993543812904498</controlfield><controlfield tag="005">20231214133137.0</controlfield><controlfield tag="006">m o d </controlfield><controlfield tag="007">cr|mn|---annan</controlfield><controlfield tag="008">202102s2017 xx |||||o ||| 0|eng d</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(CKB)4100000002484702</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(oapen)https://directory.doabooks.org/handle/20.500.12854/50187</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(EXLCZ)994100000002484702</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Saparna Pai</subfield><subfield code="4">auth</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Inflammation in the CNS: Advancing the Field Using Intravital Imaging</subfield></datafield><datafield tag="246" ind1=" " ind2=" "><subfield code="a">Inflammation in the CNS</subfield></datafield><datafield tag="260" ind1=" " ind2=" "><subfield code="b">Frontiers Media SA</subfield><subfield code="c">2017</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 electronic resource (108 p.)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">computer</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">online resource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="1" ind2=" "><subfield code="a">Frontiers Research Topics</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">Inflammation of the CNS can have devastating, long-lived, and in some cases fatal consequences for patients. The stimuli that can induce CNS inflammation are diverse, and include infectious agents, autoimmune responses against CNS-expressed antigens, and sterile inflammation following ischemia or traumatic injury. In these conditions, cells of the immune system play central roles in promulgation and resolution of the inflammatory response. However, the immunological mechanisms at work in these diverse responses differ according to the nature of the response. Our understanding of the actions of immune cells in the CNS has been restricted by the difficulty in visualising leukocytes as they undergo recruitment from the cerebral microvasculature and following their entry into the CNS parenchyma. However, advances in in vivo microscopy over the last 10-15 years have overcome many of these difficulties, and studies using these forms of microscopy have revealed a wealth of new information regarding the cellular and molecular mechanisms of CNS inflammation. This Research Topic brings together state of the art reviews examining the use of in vivo imaging in investigating inflammation and leukocyte behaviour in the CNS. Papers in this Research Topic describe how in vivo microscopy has increased our understanding of the actions of immune cells in the inflamed CNS, following various stimuli including autoimmunity, infection and sterile inflammation.</subfield></datafield><datafield tag="546" ind1=" " ind2=" "><subfield code="a">English</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Intravital Imaging</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Brain</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Inflammation</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">CNS disorders</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">Leukocytes</subfield></datafield><datafield tag="776" ind1=" " ind2=" "><subfield code="z">2-88945-364-2</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Wolfgang Weninger</subfield><subfield code="4">auth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Michael J. Hickey</subfield><subfield code="4">auth</subfield></datafield><datafield tag="906" ind1=" " ind2=" "><subfield code="a">BOOK</subfield></datafield><datafield tag="ADM" ind1=" " ind2=" "><subfield code="b">2023-12-15 05:43:59 Europe/Vienna</subfield><subfield code="f">system</subfield><subfield code="c">marc21</subfield><subfield code="a">2018-03-10 17:16:05 Europe/Vienna</subfield><subfield code="g">false</subfield></datafield><datafield tag="AVE" ind1=" " ind2=" "><subfield code="i">DOAB Directory of Open Access Books</subfield><subfield code="P">DOAB Directory of Open Access Books</subfield><subfield code="x">https://eu02.alma.exlibrisgroup.com/view/uresolver/43ACC_OEAW/openurl?u.ignore_date_coverage=true&portfolio_pid=5337406460004498&Force_direct=true</subfield><subfield code="Z">5337406460004498</subfield><subfield code="b">Available</subfield><subfield code="8">5337406460004498</subfield></datafield></record></collection> |