Signalling Pathways in Embryonic Development
The formation of a complex multicellular organism from a single cell is one of the most amazing processes of biology. Embryonic development is characterised by the careful regulation of cellular behaviours such that cells proliferate, migrate, differentiate and form tissues at the correct place and...
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Superior document: | Frontiers Research Topics |
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Year of Publication: | 2017 |
Language: | English |
Series: | Frontiers Research Topics
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Physical Description: | 1 electronic resource (177 p.) |
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Andrea E. Munsterberg auth Signalling Pathways in Embryonic Development Frontiers Media SA 2017 1 electronic resource (177 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier Frontiers Research Topics The formation of a complex multicellular organism from a single cell is one of the most amazing processes of biology. Embryonic development is characterised by the careful regulation of cellular behaviours such that cells proliferate, migrate, differentiate and form tissues at the correct place and time. These processes are genetically controlled and depend both on the history of cells, their lineage, and on the activities of signalling pathways, which coordinate the cell interactions leading to organogenesis. The aim of the Frontiers research topic “Signalling pathways in embryonic development” has been to provide a forum for experts in cell and developmental biology to share recent advances in the field of signalling during embryonic development. Sixteen articles in a variety of formats are united in this Topic, offering a valuable collection for researchers looking for an update in the knowledge of signalling pathways operating during embryogenesis. The works, focused mainly on vertebrates, explore different aspects of this theme from cell communication to organ formation and have implications for areas as distant as evolution or pathology. Understanding developmental signalling pathways is important for several reasons. It gives us information about basic mechanisms of cell function and interactions needed for morphogenesis and organogenesis. It uncovers the basis of congenital malformations, since errors at any step of cell signalling during development are a major cause of defects. This fundamental insight gives us clues to understand the mechanisms operating in evolution that explain diversity in form and function. And finally, it allows the identification of possible causes of disease in the adult organism (such as cancer or degenerative diseases) pinpointing possible targets for therapeutic approaches. English development Shh Fgf Notch embryo Signalling organogenesis Wnt 2-88945-346-4 Sigmar Stricker auth Juan J. Sanz-Ezquerro auth |
language |
English |
format |
eBook |
author |
Andrea E. Munsterberg |
spellingShingle |
Andrea E. Munsterberg Signalling Pathways in Embryonic Development Frontiers Research Topics |
author_facet |
Andrea E. Munsterberg Sigmar Stricker Juan J. Sanz-Ezquerro |
author_variant |
a e m aem |
author2 |
Sigmar Stricker Juan J. Sanz-Ezquerro |
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s s ss j j s e jjse |
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Andrea E. Munsterberg |
title |
Signalling Pathways in Embryonic Development |
title_full |
Signalling Pathways in Embryonic Development |
title_fullStr |
Signalling Pathways in Embryonic Development |
title_full_unstemmed |
Signalling Pathways in Embryonic Development |
title_auth |
Signalling Pathways in Embryonic Development |
title_new |
Signalling Pathways in Embryonic Development |
title_sort |
signalling pathways in embryonic development |
series |
Frontiers Research Topics |
series2 |
Frontiers Research Topics |
publisher |
Frontiers Media SA |
publishDate |
2017 |
physical |
1 electronic resource (177 p.) |
isbn |
2-88945-346-4 |
illustrated |
Not Illustrated |
work_keys_str_mv |
AT andreaemunsterberg signallingpathwaysinembryonicdevelopment AT sigmarstricker signallingpathwaysinembryonicdevelopment AT juanjsanzezquerro signallingpathwaysinembryonicdevelopment |
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Frontiers Research Topics |
is_hierarchy_title |
Signalling Pathways in Embryonic Development |
container_title |
Frontiers Research Topics |
author2_original_writing_str_mv |
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