Computational and Experimental Approaches in Multi-Target Pharmacology

Computational and Experimental Approaches in Multi-Target Pharmacology

The next frontier in pharmacology is the development of multi-target strategies in which pathological processes are controlled by pharmacologically manipulating them at many different points at once. Designing multi-target strategies will require deep understanding of the complex physiology that und...

Full description

Saved in:
Bibliographic Details
Superior document:Frontiers Research Topics
:
Thomas J. Anastasio
Year of Publication:2017
Language:English
Series:Frontiers Research Topics
Physical Description:1 electronic resource (122 p.)
Tags: Add Tag
No Tags, Be the first to tag this record!
id 993543790404498
ctrlnum (CKB)4100000002484657
(oapen)https://directory.doabooks.org/handle/20.500.12854/43699
(EXLCZ)994100000002484657
collection bib_alma
record_format marc
spelling Thomas J. Anastasio auth
Computational and Experimental Approaches in Multi-Target Pharmacology
Frontiers Media SA 2017
1 electronic resource (122 p.)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Frontiers Research Topics
The next frontier in pharmacology is the development of multi-target strategies in which pathological processes are controlled by pharmacologically manipulating them at many different points at once. Designing multi-target strategies will require deep understanding of the complex physiology that underlies pathological processes. It will also require the development of single drugs with multiple targets, or combinations of drugs with compatible pharmacokinetics that work synergistically to maximize desirable effects while minimizing unwanted side effects. This e-Book contains ten original articles, each addressing a different aspect of this challenge. Together they open new perspectives and show the way forward in the development of multi-target therapeutics.
English
systems biology
computer modeling
drug repurposing
synergy
drug discovery
drug combination
high throughput screening
multidrug therapeutics
polypharmacy
multifactorial process
2-88945-252-2
language English
format eBook
author Thomas J. Anastasio
spellingShingle Thomas J. Anastasio
Computational and Experimental Approaches in Multi-Target Pharmacology
Frontiers Research Topics
author_facet Thomas J. Anastasio
author_variant t j a tja
author_sort Thomas J. Anastasio
title Computational and Experimental Approaches in Multi-Target Pharmacology
title_full Computational and Experimental Approaches in Multi-Target Pharmacology
title_fullStr Computational and Experimental Approaches in Multi-Target Pharmacology
title_full_unstemmed Computational and Experimental Approaches in Multi-Target Pharmacology
title_auth Computational and Experimental Approaches in Multi-Target Pharmacology
title_new Computational and Experimental Approaches in Multi-Target Pharmacology
title_sort computational and experimental approaches in multi-target pharmacology
series Frontiers Research Topics
series2 Frontiers Research Topics
publisher Frontiers Media SA
publishDate 2017
physical 1 electronic resource (122 p.)
isbn 2-88945-252-2
illustrated Not Illustrated
work_keys_str_mv AT thomasjanastasio computationalandexperimentalapproachesinmultitargetpharmacology
status_str n
ids_txt_mv (CKB)4100000002484657
(oapen)https://directory.doabooks.org/handle/20.500.12854/43699
(EXLCZ)994100000002484657
carrierType_str_mv cr
hierarchy_parent_title Frontiers Research Topics
is_hierarchy_title Computational and Experimental Approaches in Multi-Target Pharmacology
container_title Frontiers Research Topics
_version_ 1787548770178695168
fullrecord <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01914nam-a2200385z--4500</leader><controlfield tag="001">993543790404498</controlfield><controlfield tag="005">20231214133351.0</controlfield><controlfield tag="006">m o d </controlfield><controlfield tag="007">cr|mn|---annan</controlfield><controlfield tag="008">202102s2017 xx |||||o ||| 0|eng d</controlfield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(CKB)4100000002484657</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(oapen)https://directory.doabooks.org/handle/20.500.12854/43699</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(EXLCZ)994100000002484657</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="100" ind1="1" ind2=" "><subfield code="a">Thomas J. Anastasio</subfield><subfield code="4">auth</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Computational and Experimental Approaches in Multi-Target Pharmacology</subfield></datafield><datafield tag="260" ind1=" " ind2=" "><subfield code="b">Frontiers Media SA</subfield><subfield code="c">2017</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">1 electronic resource (122 p.)</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="a">text</subfield><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="a">computer</subfield><subfield code="b">c</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="a">online resource</subfield><subfield code="b">cr</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="1" ind2=" "><subfield code="a">Frontiers Research Topics</subfield></datafield><datafield tag="520" ind1=" " ind2=" "><subfield code="a">The next frontier in pharmacology is the development of multi-target strategies in which pathological processes are controlled by pharmacologically manipulating them at many different points at once. Designing multi-target strategies will require deep understanding of the complex physiology that underlies pathological processes. It will also require the development of single drugs with multiple targets, or combinations of drugs with compatible pharmacokinetics that work synergistically to maximize desirable effects while minimizing unwanted side effects. This e-Book contains ten original articles, each addressing a different aspect of this challenge. Together they open new perspectives and show the way forward in the development of multi-target therapeutics.</subfield></datafield><datafield tag="546" ind1=" " ind2=" "><subfield code="a">English</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">systems biology</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">computer modeling</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">drug repurposing</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">synergy</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">drug discovery</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">drug combination</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">high throughput screening</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">multidrug therapeutics</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">polypharmacy</subfield></datafield><datafield tag="653" ind1=" " ind2=" "><subfield code="a">multifactorial process</subfield></datafield><datafield tag="776" ind1=" " ind2=" "><subfield code="z">2-88945-252-2</subfield></datafield><datafield tag="906" ind1=" " ind2=" "><subfield code="a">BOOK</subfield></datafield><datafield tag="ADM" ind1=" " ind2=" "><subfield code="b">2023-12-15 05:51:46 Europe/Vienna</subfield><subfield code="f">system</subfield><subfield code="c">marc21</subfield><subfield code="a">2018-03-10 17:16:05 Europe/Vienna</subfield><subfield code="g">false</subfield></datafield><datafield tag="AVE" ind1=" " ind2=" "><subfield code="i">DOAB Directory of Open Access Books</subfield><subfield code="P">DOAB Directory of Open Access Books</subfield><subfield code="x">https://eu02.alma.exlibrisgroup.com/view/uresolver/43ACC_OEAW/openurl?u.ignore_date_coverage=true&amp;portfolio_pid=5337399700004498&amp;Force_direct=true</subfield><subfield code="Z">5337399700004498</subfield><subfield code="b">Available</subfield><subfield code="8">5337399700004498</subfield></datafield></record></collection>

Similar Items