Molecular Chaperones and Neurodegeneration
Molecular chaperones or heat-shock proteins (HSPs) play essential roles in safeguarding structural stability and preventing misfolding and aggregation of proteins, and maintaining the proteome functionality in the cell. For over two decades until the present time, new functions have been discovered...
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Superior document: | Frontiers Research Topics |
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Year of Publication: | 2017 |
Language: | English |
Series: | Frontiers Research Topics
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Physical Description: | 1 electronic resource (180 p.) |
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Cintia Roodveldt auth Molecular Chaperones and Neurodegeneration Frontiers Media SA 2017 1 electronic resource (180 p.) text txt rdacontent computer c rdamedia online resource cr rdacarrier Frontiers Research Topics Molecular chaperones or heat-shock proteins (HSPs) play essential roles in safeguarding structural stability and preventing misfolding and aggregation of proteins, and maintaining the proteome functionality in the cell. For over two decades until the present time, new functions have been discovered and several molecular mechanisms have been elucidated for many chaperones, while the field is being continuously challenged by new open questions. Probably as a consequence of the increasing research on the molecular bases of neurodegenerative diseases, and the realisation that many such disorders are linked to protein misfolding processes, unleashing the roles and mechanisms of chaperones in the context of neurodegeneration has become a prime scientific goal. This e-book contains a diversity of reviews, perspective and original research articles highlighting the importance and potential of this emerging subject. English molecular chaperone therapeutics neurodegenerative disease heat-shock response protein misfolding neuroprotection neurodegeneration heat-shock protein proteostasis amyloid protein 2-88945-342-1 Janice E. Braun auth Tiago F. Outeiro auth |
language |
English |
format |
eBook |
author |
Cintia Roodveldt |
spellingShingle |
Cintia Roodveldt Molecular Chaperones and Neurodegeneration Frontiers Research Topics |
author_facet |
Cintia Roodveldt Janice E. Braun Tiago F. Outeiro |
author_variant |
c r cr |
author2 |
Janice E. Braun Tiago F. Outeiro |
author2_variant |
j e b jeb t f o tfo |
author_sort |
Cintia Roodveldt |
title |
Molecular Chaperones and Neurodegeneration |
title_full |
Molecular Chaperones and Neurodegeneration |
title_fullStr |
Molecular Chaperones and Neurodegeneration |
title_full_unstemmed |
Molecular Chaperones and Neurodegeneration |
title_auth |
Molecular Chaperones and Neurodegeneration |
title_new |
Molecular Chaperones and Neurodegeneration |
title_sort |
molecular chaperones and neurodegeneration |
series |
Frontiers Research Topics |
series2 |
Frontiers Research Topics |
publisher |
Frontiers Media SA |
publishDate |
2017 |
physical |
1 electronic resource (180 p.) |
isbn |
2-88945-342-1 |
illustrated |
Not Illustrated |
work_keys_str_mv |
AT cintiaroodveldt molecularchaperonesandneurodegeneration AT janiceebraun molecularchaperonesandneurodegeneration AT tiagofouteiro molecularchaperonesandneurodegeneration |
status_str |
n |
ids_txt_mv |
(CKB)4100000002484760 (oapen)https://directory.doabooks.org/handle/20.500.12854/53828 (EXLCZ)994100000002484760 |
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cr |
hierarchy_parent_title |
Frontiers Research Topics |
is_hierarchy_title |
Molecular Chaperones and Neurodegeneration |
container_title |
Frontiers Research Topics |
author2_original_writing_str_mv |
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1787548899970383873 |
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