Molecular Chaperones and Neurodegeneration

Molecular chaperones or heat-shock proteins (HSPs) play essential roles in safeguarding structural stability and preventing misfolding and aggregation of proteins, and maintaining the proteome functionality in the cell. For over two decades until the present time, new functions have been discovered...

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Superior document:Frontiers Research Topics
:
Year of Publication:2017
Language:English
Series:Frontiers Research Topics
Physical Description:1 electronic resource (180 p.)
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spelling Cintia Roodveldt auth
Molecular Chaperones and Neurodegeneration
Frontiers Media SA 2017
1 electronic resource (180 p.)
text txt rdacontent
computer c rdamedia
online resource cr rdacarrier
Frontiers Research Topics
Molecular chaperones or heat-shock proteins (HSPs) play essential roles in safeguarding structural stability and preventing misfolding and aggregation of proteins, and maintaining the proteome functionality in the cell. For over two decades until the present time, new functions have been discovered and several molecular mechanisms have been elucidated for many chaperones, while the field is being continuously challenged by new open questions. Probably as a consequence of the increasing research on the molecular bases of neurodegenerative diseases, and the realisation that many such disorders are linked to protein misfolding processes, unleashing the roles and mechanisms of chaperones in the context of neurodegeneration has become a prime scientific goal. This e-book contains a diversity of reviews, perspective and original research articles highlighting the importance and potential of this emerging subject.
English
molecular chaperone
therapeutics
neurodegenerative disease
heat-shock response
protein misfolding
neuroprotection
neurodegeneration
heat-shock protein
proteostasis
amyloid protein
2-88945-342-1
Janice E. Braun auth
Tiago F. Outeiro auth
language English
format eBook
author Cintia Roodveldt
spellingShingle Cintia Roodveldt
Molecular Chaperones and Neurodegeneration
Frontiers Research Topics
author_facet Cintia Roodveldt
Janice E. Braun
Tiago F. Outeiro
author_variant c r cr
author2 Janice E. Braun
Tiago F. Outeiro
author2_variant j e b jeb
t f o tfo
author_sort Cintia Roodveldt
title Molecular Chaperones and Neurodegeneration
title_full Molecular Chaperones and Neurodegeneration
title_fullStr Molecular Chaperones and Neurodegeneration
title_full_unstemmed Molecular Chaperones and Neurodegeneration
title_auth Molecular Chaperones and Neurodegeneration
title_new Molecular Chaperones and Neurodegeneration
title_sort molecular chaperones and neurodegeneration
series Frontiers Research Topics
series2 Frontiers Research Topics
publisher Frontiers Media SA
publishDate 2017
physical 1 electronic resource (180 p.)
isbn 2-88945-342-1
illustrated Not Illustrated
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is_hierarchy_title Molecular Chaperones and Neurodegeneration
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